DK2010565T3 - Fremgangsmåde til produktion af rekombinant protein i CHO-celler - Google Patents
Fremgangsmåde til produktion af rekombinant protein i CHO-cellerInfo
- Publication number
- DK2010565T3 DK2010565T3 DK07748645.4T DK07748645T DK2010565T3 DK 2010565 T3 DK2010565 T3 DK 2010565T3 DK 07748645 T DK07748645 T DK 07748645T DK 2010565 T3 DK2010565 T3 DK 2010565T3
- Authority
- DK
- Denmark
- Prior art keywords
- recombinant protein
- seq
- cho cells
- producing recombinant
- cell
- Prior art date
Links
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title abstract 2
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title abstract 2
- 210000004978 chinese hamster ovary cell Anatomy 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 102000002812 Heat-Shock Proteins Human genes 0.000 abstract 2
- 108010004889 Heat-Shock Proteins Proteins 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 241000699802 Cricetulus griseus Species 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7156—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/07—Heat shock proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74528906P | 2006-04-21 | 2006-04-21 | |
| PCT/SG2007/000100 WO2007123489A1 (en) | 2006-04-21 | 2007-04-16 | Method for recombinant protein production in cho cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2010565T3 true DK2010565T3 (da) | 2012-05-29 |
Family
ID=38441948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07748645.4T DK2010565T3 (da) | 2006-04-21 | 2007-04-16 | Fremgangsmåde til produktion af rekombinant protein i CHO-celler |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090170165A1 (da) |
| EP (1) | EP2010565B1 (da) |
| AT (1) | ATE546464T1 (da) |
| DK (1) | DK2010565T3 (da) |
| WO (1) | WO2007123489A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100015713A1 (en) * | 2005-06-28 | 2010-01-21 | Scott Deeter | Components of cell culture media produced from plant cells |
| US20090186358A1 (en) * | 2007-12-21 | 2009-07-23 | Wyeth | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof |
| CN101952303A (zh) * | 2008-02-25 | 2011-01-19 | 诺维信公司 | 提高目标蛋白质的表达产率的方法 |
| US20120315697A1 (en) | 2009-02-20 | 2012-12-13 | Ventria Bioscience | Cell Culture Media Containing Combinations of Proteins |
| ES2358829B1 (es) * | 2009-10-23 | 2012-06-25 | Lipotec, S.A. | Péptidos útiles en el tratamiento y/o cuidado de la piel, mucosas y/o cabello y su uso en composiciones cosméticas o farmacéuticas. |
| EP2829608A1 (en) | 2013-07-23 | 2015-01-28 | Universität Bielefeld | Method for recombinant protein production in mammalian cells |
| CL2016001661A1 (es) | 2016-06-29 | 2017-03-03 | Univ Chile | Promotor hibrido de ß-actina (de cricetulus griseus) y citomegalovirus (cmv), con región rica en dinucleótidos, citosina-guanina, vectores, líneas celulares, procedimiento para producir proteínas recombinantes. |
| WO2018049071A1 (en) * | 2016-09-07 | 2018-03-15 | Vanderbilt University | Vasoactive polypeptides for smooth muscle relaxation |
| JP2023535604A (ja) * | 2020-07-30 | 2023-08-18 | ファイザー・インク | 遺伝子複製を有する細胞およびその使用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5856179A (en) * | 1994-03-10 | 1999-01-05 | Genentech, Inc. | Polypeptide production in animal cell culture |
| US7362775B1 (en) * | 1996-07-02 | 2008-04-22 | Wistaria Trading, Inc. | Exchange mechanisms for digital information packages with bandwidth securitization, multichannel digital watermarks, and key management |
| US20040157289A1 (en) | 2002-09-06 | 2004-08-12 | Salerno John C. | Protein expression system |
| US7244616B2 (en) | 2003-06-27 | 2007-07-17 | Bayer Pharmaceuticals Corporation | Use of molecular chaperones for the enhanced production of secreted, recombinant proteins in mammalian cells |
-
2007
- 2007-04-16 DK DK07748645.4T patent/DK2010565T3/da active
- 2007-04-16 EP EP07748645A patent/EP2010565B1/en not_active Not-in-force
- 2007-04-16 WO PCT/SG2007/000100 patent/WO2007123489A1/en not_active Ceased
- 2007-04-16 AT AT07748645T patent/ATE546464T1/de active
-
2008
- 2008-10-21 US US12/255,119 patent/US20090170165A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20090170165A1 (en) | 2009-07-02 |
| WO2007123489A1 (en) | 2007-11-01 |
| EP2010565B1 (en) | 2012-02-22 |
| EP2010565A1 (en) | 2009-01-07 |
| ATE546464T1 (de) | 2012-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK2010565T3 (da) | Fremgangsmåde til produktion af rekombinant protein i CHO-celler | |
| DK1824970T3 (da) | Thricoderma reesei-glycoamylase og homologer heraf | |
| EA201001435A1 (ru) | Клетка, ферментирующая сахар-пентозу | |
| MX2012015142A (es) | Polipeptidos que tiene actividad beta-glucosidasa y usos del mismo. | |
| NZ595500A (en) | Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them | |
| BRPI0720048A8 (pt) | Proteínas de dedo de zinco não-canônicas otimizadas | |
| DK1836299T3 (da) | Polypeptider, der har cellobiohydrolaseaktivitet, og polynekleotider, der koder for disse | |
| MX2011011215A (es) | Polipeptido que degrada carbohidratos y usos del mismo. | |
| BRPI0411182A (pt) | método para aumentar a toleráncia de uma planta ao estresse abiótico, método para aumentar a biomassa de uma planta, construto de ácido nucléico, polipeptìdio isolado e célula de planta | |
| RU2007141683A (ru) | Вариантная форма урат-оксидазы и ее использование | |
| MY187542A (en) | Carbohydrate degrading polypeptide and uses thereof | |
| IN2012DN03823A (da) | ||
| NZ608972A (en) | Engineered nucleic acids and methods of use thereof | |
| GB201201178D0 (en) | Novel enzymes | |
| WO2008023247A3 (en) | Matrix attachment regions (mars) for increasing transcription and uses thereof | |
| DE602004028000D1 (de) | Tuberkulose vaccine mit verbesserter effizienz | |
| EA201300056A1 (ru) | Полипептид с активностью ацетилксиланэстеразы и его применения | |
| WO2011021105A3 (en) | Generation and reproduction of dna sequences and analysis of polymorphisms and mutations by using error-correcting codes | |
| MX2008001513A (es) | Secuencias de acidos nucleicos que codifican proteinas asociadas con respuesta a estres abiotico y celulas vegetales y plantas con aumento de tolerancia a estres ambiental. | |
| EA201300059A1 (ru) | Полипептид, обладающий активностью сволленина, и его применение | |
| RU2013104989A (ru) | Элемент днк, обладающий активностью, направленной на усиление экспрессии чужеродного гена | |
| WO2009011259A1 (ja) | 新規ｄｎａ断片およびそれを含む組換えベクター、それらによって形質転換された形質転換体、ならびにそれらの利用 | |
| DK1877551T3 (da) | Polypeptider, der har endoglucanaseaktivitet, og polynukleotider, der koder for samme | |
| WO2011154611A3 (en) | A method for enhanced protein synthesis | |
| IN2012DN01315A (da) |