DK1937261T3 - Hidtil ukendte azabicyclo[3.2.1]oct-2-en-derivater og anvendelse deraf som monoamin-neurotransmitter-genoptagelseshæmmere - Google Patents

Hidtil ukendte azabicyclo[3.2.1]oct-2-en-derivater og anvendelse deraf som monoamin-neurotransmitter-genoptagelseshæmmere

Info

Publication number
DK1937261T3
DK1937261T3 DK06778387.8T DK06778387T DK1937261T3 DK 1937261 T3 DK1937261 T3 DK 1937261T3 DK 06778387 T DK06778387 T DK 06778387T DK 1937261 T3 DK1937261 T3 DK 1937261T3
Authority
DK
Denmark
Prior art keywords
oct
reuptake inhibitors
monoamine neurotransmitter
neurotransmitter reuptake
ene derivatives
Prior art date
Application number
DK06778387.8T
Other languages
Danish (da)
English (en)
Inventor
Dan Peters
Bjarne H Dahl
John Paul Redrobe
Elsebet Oestergaard Nielsen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of DK1937261T3 publication Critical patent/DK1937261T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Child & Adolescent Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK06778387.8T 2005-09-01 2006-08-30 Hidtil ukendte azabicyclo[3.2.1]oct-2-en-derivater og anvendelse deraf som monoamin-neurotransmitter-genoptagelseshæmmere DK1937261T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200501218 2005-09-01
US71336705P 2005-09-02 2005-09-02
PCT/EP2006/065804 WO2007025978A1 (en) 2005-09-01 2006-08-30 Novel azabicyclo[3.2.1]oct-2-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Publications (1)

Publication Number Publication Date
DK1937261T3 true DK1937261T3 (da) 2010-06-07

Family

ID=38951394

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06778387.8T DK1937261T3 (da) 2005-09-01 2006-08-30 Hidtil ukendte azabicyclo[3.2.1]oct-2-en-derivater og anvendelse deraf som monoamin-neurotransmitter-genoptagelseshæmmere

Country Status (13)

Country Link
US (1) US20100286193A1 (cg-RX-API-DMAC7.html)
EP (1) EP1937261B1 (cg-RX-API-DMAC7.html)
JP (1) JP2009507002A (cg-RX-API-DMAC7.html)
CN (1) CN101267820A (cg-RX-API-DMAC7.html)
AR (1) AR057788A1 (cg-RX-API-DMAC7.html)
AT (1) ATE459354T1 (cg-RX-API-DMAC7.html)
AU (1) AU2006286476A1 (cg-RX-API-DMAC7.html)
CA (1) CA2621162A1 (cg-RX-API-DMAC7.html)
DE (1) DE602006012711D1 (cg-RX-API-DMAC7.html)
DK (1) DK1937261T3 (cg-RX-API-DMAC7.html)
NZ (1) NZ565469A (cg-RX-API-DMAC7.html)
TW (1) TW200744590A (cg-RX-API-DMAC7.html)
WO (1) WO2007025978A1 (cg-RX-API-DMAC7.html)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE03446B1 (et) * 1995-10-13 2001-06-15 Neurosearch A/S 8-asabitsüklo[3.2.1]okt-2-eeni derivaadid, nende valmistamine ja kasutamine
GB9624611D0 (en) * 1996-11-26 1997-01-15 Zeneca Ltd Bicyclic amine compounds

Also Published As

Publication number Publication date
WO2007025978A1 (en) 2007-03-08
NZ565469A (en) 2010-11-26
CN101267820A (zh) 2008-09-17
US20100286193A1 (en) 2010-11-11
EP1937261A1 (en) 2008-07-02
AU2006286476A1 (en) 2007-03-08
JP2009507002A (ja) 2009-02-19
EP1937261B1 (en) 2010-03-03
CA2621162A1 (en) 2007-03-08
TW200744590A (en) 2007-12-16
DE602006012711D1 (de) 2010-04-15
ATE459354T1 (de) 2010-03-15
AR057788A1 (es) 2007-12-19

Similar Documents

Publication Publication Date Title
IL184901A0 (en) 2,4-diamino-pyridopyrimidine derivatives and their use as mtor inhibitors
DK1902037T3 (da) 2,4-diamino-pyrimidiner som auroainhibitorer
PL2049557T3 (pl) Pochodne 1-(d-glikopiranozylo)-3-(4-cyklopropylofenylometylo)-4-fluorowcoindolu i ich zastosowanie jako inhibitorów sglt
ZA200709856B (en) Fluorene derivatives,compositions containing said derivatives and the use thereof
DK1948149T4 (da) Formulering, som omfatter metformin og vildagliptin
NO20083147L (no) Anti-OX40L-antistoffer og fremgangsmater for anvendelse av disse
ZA200709691B (en) N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
DK2094263T3 (da) 2-adamantyl-butyramidderivater som selektive 11 beta-hsd1-inhibitorer
CY1109916T1 (el) Βενζιμιδαζολο-θειοφαινικες ενωσεις ως plk αναστολεις
IS8212A (is) Nýjar 8-aza-bísýkló[3.2.1]oktanafleiður og notkunþeirra sem mónóamín-taugaboðefnaendurupptökuhindrar
ZA200706672B (en) 2,4-Diamino-pyridopyrimidine derivatives and their use as mTOR inhibitors
NO20083593L (no) Anti-EphrinB2-antistoffer og fremgangsmater for anvendelse av disse
ZA200800408B (en) Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof
IL179371A0 (en) 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitor
EP1962852A4 (en) COMPOUNDS, COMPOSITIONS AND METHODS
IL182738A0 (en) Enantiomers of 3-heteroaryl-8h-8-azabicyclo(3.2.1)oct-2-ene and their use as monoamine neurotransmitter re-uptake inhibitors
ATE496049T1 (de) Als monoamin wiederaufnahmehemmer geeignete 8- azabicycloä3.2.1üoctanderivate
ZA200802774B (en) Benzothiadiazolyphenylalkylamine derivatives for use in the treatment of conditions ameliorated by monoamine reuptake
DK1937261T3 (da) Hidtil ukendte azabicyclo[3.2.1]oct-2-en-derivater og anvendelse deraf som monoamin-neurotransmitter-genoptagelseshæmmere
ITMI20051155A1 (it) Nuovi composti fluorurati, loro sintesi e uso.
SI1710240T1 (sl) Derivati piperazina in njihova uporaba kot zaviralci ponovnega vnosa serotonina ali kot antagonistinevrokinina
DK1853609T3 (da) Thienopyridinderivater og anvendelse deraf som hsp90-modulatorer
IL182268A0 (en) Novel naphthyl substituted azabicyclo derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
DK2029596T3 (da) 2-Alkoxy-3,4,5-trihydroxy-alkylamid-benzothiazepin, fremstilling deraf, sammensætninger indeholdende samme og anvendelse
ITTV20050061U1 (it) Portaoggetti per mobili.