AR057788A1 - Compuestos de azabiciclo[3.2.1]oct-2-eno y composicion farmaceutica - Google Patents
Compuestos de azabiciclo[3.2.1]oct-2-eno y composicion farmaceuticaInfo
- Publication number
- AR057788A1 AR057788A1 ARP060103811A ARP060103811A AR057788A1 AR 057788 A1 AR057788 A1 AR 057788A1 AR P060103811 A ARP060103811 A AR P060103811A AR P060103811 A ARP060103811 A AR P060103811A AR 057788 A1 AR057788 A1 AR 057788A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- compounds
- oct
- azabiciclo
- eno
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Gynecology & Obstetrics (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Esta presente se refiere a derivados de azabiciclo[3.2.1]oct-2-eno utiles como inhibidores de la reabsorcion del neurotransmisor de la monoamina. En otros aspectos la presente se refiere al uso de estos compuestos para preparar medicamentos y a composiciones farmacéuticas que comprenden los compuestos de la presente. Reivindicacion 1: Un compuesto de formula (1), cualquiera de sus isomeros o cualquier mezcla de sus isomeros, o una sal farmacéuticamente aceptable del mismo; donde R representa hidrogeno o alquilo; alquilo que está opcionalmente sustituido con uno o más sustituyentes independientemente seleccionados del grupo formado por: halo, trifluorometilo, trifluorometoxi, ciano, hidroxi, amino, nitro, alcoxi, cicloalcoxi, alquilo, cicloalquilo, cicloalquiloalquilo, alquenilo y alquinilo; Ra representa alquilo; y Rb representa halo, trifluorometilo, trifluorometoxi, ciano, nitro, hidroxi, alcoxi, cicloalcoxi, alcoxialquilo, cicloalcoxialquilo, alquilo, cicloalquilo, cicloalquiloalquilo, alquenilo, alquinilo, -NR'R''. -(C=O)NR'R'' o -NR'(C=O)R''; donde R' y R'' cada uno independientemente del otro son hidrogeno o alquilo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200501218 | 2005-09-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR057788A1 true AR057788A1 (es) | 2007-12-19 |
Family
ID=38951394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060103811A AR057788A1 (es) | 2005-09-01 | 2006-08-31 | Compuestos de azabiciclo[3.2.1]oct-2-eno y composicion farmaceutica |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100286193A1 (es) |
| EP (1) | EP1937261B1 (es) |
| JP (1) | JP2009507002A (es) |
| CN (1) | CN101267820A (es) |
| AR (1) | AR057788A1 (es) |
| AT (1) | ATE459354T1 (es) |
| AU (1) | AU2006286476A1 (es) |
| CA (1) | CA2621162A1 (es) |
| DE (1) | DE602006012711D1 (es) |
| DK (1) | DK1937261T3 (es) |
| NZ (1) | NZ565469A (es) |
| TW (1) | TW200744590A (es) |
| WO (1) | WO2007025978A1 (es) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69637097T2 (de) * | 1995-10-13 | 2007-09-20 | Neurosearch A/S | 8-Azabicyclo(3.2.1)Oct-2-en-Derivate, deren Herstellung und Anwendung |
| GB9624611D0 (en) * | 1996-11-26 | 1997-01-15 | Zeneca Ltd | Bicyclic amine compounds |
-
2006
- 2006-08-03 TW TW095128449A patent/TW200744590A/zh unknown
- 2006-08-30 WO PCT/EP2006/065804 patent/WO2007025978A1/en active Application Filing
- 2006-08-30 EP EP06778387A patent/EP1937261B1/en not_active Not-in-force
- 2006-08-30 DE DE602006012711T patent/DE602006012711D1/de active Active
- 2006-08-30 JP JP2008528510A patent/JP2009507002A/ja not_active Abandoned
- 2006-08-30 CN CNA2006800300207A patent/CN101267820A/zh active Pending
- 2006-08-30 NZ NZ565469A patent/NZ565469A/en unknown
- 2006-08-30 US US11/990,015 patent/US20100286193A1/en not_active Abandoned
- 2006-08-30 AT AT06778387T patent/ATE459354T1/de active
- 2006-08-30 CA CA002621162A patent/CA2621162A1/en not_active Abandoned
- 2006-08-30 DK DK06778387.8T patent/DK1937261T3/da active
- 2006-08-30 AU AU2006286476A patent/AU2006286476A1/en not_active Abandoned
- 2006-08-31 AR ARP060103811A patent/AR057788A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2621162A1 (en) | 2007-03-08 |
| US20100286193A1 (en) | 2010-11-11 |
| CN101267820A (zh) | 2008-09-17 |
| TW200744590A (en) | 2007-12-16 |
| WO2007025978A1 (en) | 2007-03-08 |
| NZ565469A (en) | 2010-11-26 |
| EP1937261B1 (en) | 2010-03-03 |
| ATE459354T1 (de) | 2010-03-15 |
| DK1937261T3 (da) | 2010-06-07 |
| DE602006012711D1 (de) | 2010-04-15 |
| AU2006286476A1 (en) | 2007-03-08 |
| JP2009507002A (ja) | 2009-02-19 |
| EP1937261A1 (en) | 2008-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |