DK1906916T3 - Oftalmisk suspension, der omfatter et oftalmisk lægemiddel, en poloxamin og et tonicitetsregulerende glycolbaseret middel, anvendelse af sammensætningen til fremstilling af et medikament til behandling af oftalmiske lidelser - Google Patents
Oftalmisk suspension, der omfatter et oftalmisk lægemiddel, en poloxamin og et tonicitetsregulerende glycolbaseret middel, anvendelse af sammensætningen til fremstilling af et medikament til behandling af oftalmiske lidelserInfo
- Publication number
- DK1906916T3 DK1906916T3 DK06759259T DK06759259T DK1906916T3 DK 1906916 T3 DK1906916 T3 DK 1906916T3 DK 06759259 T DK06759259 T DK 06759259T DK 06759259 T DK06759259 T DK 06759259T DK 1906916 T3 DK1906916 T3 DK 1906916T3
- Authority
- DK
- Denmark
- Prior art keywords
- ophthalmic
- poloxamine
- medicament
- manufacture
- treatment
- Prior art date
Links
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 title abstract 2
- 229940023490 ophthalmic product Drugs 0.000 title abstract 2
- 229920001987 poloxamine Polymers 0.000 title abstract 2
- 239000003732 agents acting on the eye Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940100654 ophthalmic suspension Drugs 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67951005P | 2005-05-10 | 2005-05-10 | |
| PCT/US2006/017607 WO2006121964A2 (en) | 2005-05-10 | 2006-05-08 | Ophthalmic suspension comprising an ophthalmic drug, a poloxamine and a glycol tonicity-adjusting agent, use of said composition for the manufacture of a medicament for treating ophthalmic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1906916T3 true DK1906916T3 (da) | 2009-01-19 |
Family
ID=37087751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06759259T DK1906916T3 (da) | 2005-05-10 | 2006-05-08 | Oftalmisk suspension, der omfatter et oftalmisk lægemiddel, en poloxamin og et tonicitetsregulerende glycolbaseret middel, anvendelse af sammensætningen til fremstilling af et medikament til behandling af oftalmiske lidelser |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20060257486A1 (enExample) |
| EP (1) | EP1906916B1 (enExample) |
| JP (1) | JP4968955B2 (enExample) |
| KR (1) | KR20080011311A (enExample) |
| CN (1) | CN101175476B (enExample) |
| AT (1) | ATE412402T1 (enExample) |
| AU (1) | AU2006244245B2 (enExample) |
| BR (1) | BRPI0608774A2 (enExample) |
| CA (1) | CA2607014A1 (enExample) |
| CY (1) | CY1108676T1 (enExample) |
| DE (1) | DE602006003438D1 (enExample) |
| DK (1) | DK1906916T3 (enExample) |
| ES (1) | ES2313670T3 (enExample) |
| MX (1) | MX2007014084A (enExample) |
| PL (1) | PL1906916T3 (enExample) |
| PT (1) | PT1906916E (enExample) |
| SI (1) | SI1906916T1 (enExample) |
| WO (1) | WO2006121964A2 (enExample) |
| ZA (1) | ZA200709296B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1885336T1 (sl) * | 2005-05-10 | 2009-08-31 | Alcon Inc | Suspenzijske formulacije, ki obsegajo aktivno sestavino, poloksamerni ali meroksapolni surfaktant in glikol, in njihova uporaba za pripravo zdravila za zdravljenje oftalmičnih motenj |
| TW200812575A (en) * | 2006-04-28 | 2008-03-16 | Alcon Inc | Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye |
| TW201023912A (en) | 2008-12-05 | 2010-07-01 | Alcon Res Ltd | Pharmaceutical suspension |
| US8912236B2 (en) * | 2009-03-03 | 2014-12-16 | Alcon Research, Ltd. | Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (RTKi) compounds to the eye |
| CN105362221A (zh) * | 2009-03-03 | 2016-03-02 | 爱尔康研究有限公司 | 向眼部递送受体酪氨酸激酶抑制性(RTKi)化合物的药物组合物 |
| HUE038821T2 (hu) * | 2009-12-03 | 2018-11-28 | Novartis Ag | Karboxivinil polimert tartalmazó nanorészecske szuszpenziók |
| WO2011071995A2 (en) | 2009-12-08 | 2011-06-16 | Case Western Reserve University | Compounds and methods of treating ocular disorders |
| CN103079595B (zh) * | 2010-08-27 | 2015-11-25 | 若素制药株式会社 | 滴眼用水性组合物 |
| US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
| CN104706579A (zh) * | 2015-03-12 | 2015-06-17 | 广州仁恒医药科技有限公司 | 一种夫西地酸滴眼液及其制备方法 |
| CN111285845B (zh) * | 2020-02-11 | 2021-01-01 | 深圳厚存纳米药业有限公司 | 末端官能团化的泊洛沙胺衍生物 |
| US12049606B2 (en) * | 2021-01-12 | 2024-07-30 | Johnson & Johnson Vision Care, Inc. | Compositions for ophthalmologic devices |
| CN116867480A (zh) * | 2021-02-10 | 2023-10-10 | 洛利克斯治疗有限公司 | 眼部递送罗氟司特的方法 |
| US12102622B2 (en) * | 2021-02-10 | 2024-10-01 | Iolyx Therapeutics, Inc. | Methods for ophthalmic delivery of roflumilast |
| US12263160B2 (en) | 2021-09-22 | 2025-04-01 | Iolyx Therapeutics, Inc. | Methods of treating ocular inflammatory diseases |
| IL319352A (en) * | 2022-09-15 | 2025-05-01 | Arcutis Biotherapeutics Inc | Pharmaceutical preparations of roflumilast and solvents capable of dissolving high amounts of the drug |
| CN118032955A (zh) * | 2022-11-14 | 2024-05-14 | 上海方予健康医药科技有限公司 | 一种制剂中表面活性剂含量的测定方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4313949A (en) * | 1979-09-26 | 1982-02-02 | A. H. Robins Company, Inc. | Method of producing an inhibitory effect on blood platelet aggregation |
| EP0348527B1 (en) * | 1987-12-25 | 1993-06-23 | Santen Pharmaceutical Co., Ltd. | Antiallergic eye drop |
| US4910225A (en) * | 1988-01-27 | 1990-03-20 | Senju Pharmaceutical Co., Ltd. | Locally administrable therapeutic composition for inflammatory disease |
| US5521222A (en) * | 1989-09-28 | 1996-05-28 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| US5461081A (en) * | 1989-09-28 | 1995-10-24 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| US5369095A (en) * | 1990-02-14 | 1994-11-29 | Alcon Laboratories, Inc. | Compositions and method comprising substituted glycosides as mucus membrane permeation enhancers |
| US5631005A (en) * | 1994-09-21 | 1997-05-20 | Alcon Laboratories, Inc. | Use of amidoamines in ophthalmic compositions |
| US5631004A (en) * | 1993-09-30 | 1997-05-20 | Alcon Laboratories, Inc. | Use of sustained release antibiotic compositions in ophthalmic surgical procedures |
| US5540930A (en) * | 1993-10-25 | 1996-07-30 | Pharmos Corporation | Suspension of loteprednol etabonate for ear, eye, or nose treatment |
| US5475034A (en) * | 1994-06-06 | 1995-12-12 | Alcon Laboratories, Inc. | Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders |
| JPH10158188A (ja) * | 1996-11-29 | 1998-06-16 | Senju Pharmaceut Co Ltd | 角膜治療用組成物 |
| BR9806123A (pt) * | 1997-07-29 | 1999-08-31 | Alcon Lab Inc | Soluções condicionantes para cuidado de lente de contato dura |
| US6037328A (en) * | 1998-12-22 | 2000-03-14 | Bausch & Lomb Incorporated | Method and composition for rewetting and preventing deposits on contact lens |
| US6482799B1 (en) * | 1999-05-25 | 2002-11-19 | The Regents Of The University Of California | Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial |
| IT1313610B1 (it) * | 1999-08-09 | 2002-09-09 | S I F I Societa Ind Farmaceuti | Processo per la preparazione di formulazioni acquose per uso oftalmico |
| US6582724B2 (en) * | 1999-12-16 | 2003-06-24 | Dermatrends, Inc. | Dual enhancer composition for topical and transdermal drug delivery |
| EP1249249A1 (en) * | 2000-12-12 | 2002-10-16 | Menicon Co., Ltd. | Ophthalmic composition |
| AR030346A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico |
| AR031135A1 (es) * | 2000-10-10 | 2003-09-10 | Upjohn Co | Composiciones de antibiotico topico para el tratamiento de infecciones oculares |
| US20020115578A1 (en) * | 2000-12-14 | 2002-08-22 | Groemminger Suzanne F. | Composition for cleaning and wetting contact lenses |
| US6646003B2 (en) * | 2001-04-02 | 2003-11-11 | Alcon, Inc. | Method of treating ocular inflammatory and angiogenesis-related disorders of the posterior segment of the eye using an amide derivative of flurbiprofen or ketorolac |
| JP2003137775A (ja) * | 2001-10-31 | 2003-05-14 | Menicon Co Ltd | 眼科用組成物 |
| US20030133905A1 (en) * | 2001-12-20 | 2003-07-17 | Zhenze Hu | Composition for treating contact lenses in the eye |
| US6765001B2 (en) * | 2001-12-21 | 2004-07-20 | Medicis Pharmaceutical Corporation | Compositions and methods for enhancing corticosteroid delivery |
| US7119112B2 (en) * | 2002-02-28 | 2006-10-10 | Icagen, Inc. | Sulfonamides as potassium channel blockers |
| AU2003217810C9 (en) * | 2002-02-28 | 2008-06-12 | Icagen, Inc. | Methods for treating diseases related to intraocular pressure |
| US20040115270A1 (en) * | 2002-12-13 | 2004-06-17 | Dharmendra Jani | Absorption and controlled release of polyethers from hydrogel biomaterials |
| JPWO2004084877A1 (ja) * | 2003-03-26 | 2006-06-29 | 株式会社メニコン | 眼科用組成物 |
| TWI358290B (en) * | 2004-12-02 | 2012-02-21 | Alcon Inc | Topical nepafenac formulations |
| SI1885336T1 (sl) * | 2005-05-10 | 2009-08-31 | Alcon Inc | Suspenzijske formulacije, ki obsegajo aktivno sestavino, poloksamerni ali meroksapolni surfaktant in glikol, in njihova uporaba za pripravo zdravila za zdravljenje oftalmičnih motenj |
-
2006
- 2006-05-08 AU AU2006244245A patent/AU2006244245B2/en not_active Ceased
- 2006-05-08 CN CN200680016190XA patent/CN101175476B/zh not_active Expired - Fee Related
- 2006-05-08 DE DE602006003438T patent/DE602006003438D1/de not_active Expired - Lifetime
- 2006-05-08 US US11/429,736 patent/US20060257486A1/en not_active Abandoned
- 2006-05-08 EP EP06759259A patent/EP1906916B1/en not_active Expired - Lifetime
- 2006-05-08 WO PCT/US2006/017607 patent/WO2006121964A2/en not_active Ceased
- 2006-05-08 JP JP2008511215A patent/JP4968955B2/ja not_active Expired - Fee Related
- 2006-05-08 PL PL06759259T patent/PL1906916T3/pl unknown
- 2006-05-08 BR BRPI0608774-4A patent/BRPI0608774A2/pt not_active IP Right Cessation
- 2006-05-08 PT PT06759259T patent/PT1906916E/pt unknown
- 2006-05-08 ZA ZA200709296A patent/ZA200709296B/xx unknown
- 2006-05-08 DK DK06759259T patent/DK1906916T3/da active
- 2006-05-08 MX MX2007014084A patent/MX2007014084A/es active IP Right Grant
- 2006-05-08 SI SI200630144T patent/SI1906916T1/sl unknown
- 2006-05-08 AT AT06759259T patent/ATE412402T1/de active
- 2006-05-08 KR KR1020077027978A patent/KR20080011311A/ko not_active Ceased
- 2006-05-08 ES ES06759259T patent/ES2313670T3/es not_active Expired - Lifetime
- 2006-05-08 CA CA002607014A patent/CA2607014A1/en not_active Abandoned
-
2008
- 2008-12-10 CY CY20081101427T patent/CY1108676T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE412402T1 (de) | 2008-11-15 |
| CY1108676T1 (el) | 2014-04-09 |
| PL1906916T3 (pl) | 2009-02-27 |
| KR20080011311A (ko) | 2008-02-01 |
| AU2006244245B2 (en) | 2010-11-18 |
| JP2008540533A (ja) | 2008-11-20 |
| CN101175476A (zh) | 2008-05-07 |
| ZA200709296B (en) | 2009-01-28 |
| WO2006121964A3 (en) | 2007-03-22 |
| AU2006244245A1 (en) | 2006-11-16 |
| CN101175476B (zh) | 2011-11-16 |
| ES2313670T3 (es) | 2009-03-01 |
| CA2607014A1 (en) | 2006-11-16 |
| PT1906916E (pt) | 2008-12-10 |
| WO2006121964A2 (en) | 2006-11-16 |
| DE602006003438D1 (de) | 2008-12-11 |
| EP1906916B1 (en) | 2008-10-29 |
| US20060257486A1 (en) | 2006-11-16 |
| SI1906916T1 (sl) | 2009-02-28 |
| JP4968955B2 (ja) | 2012-07-04 |
| BRPI0608774A2 (pt) | 2010-01-26 |
| EP1906916A2 (en) | 2008-04-09 |
| MX2007014084A (es) | 2008-02-07 |
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