DK1905775T3 - Tetracykliske forbindelser, fremgangsmåder til at fremstille disse, farmaceutiske sammensætninger indeholdende disse og anvendelse heraf som dopaminreceptorligander - Google Patents

Tetracykliske forbindelser, fremgangsmåder til at fremstille disse, farmaceutiske sammensætninger indeholdende disse og anvendelse heraf som dopaminreceptorligander

Info

Publication number
DK1905775T3
DK1905775T3 DK07291135.7T DK07291135T DK1905775T3 DK 1905775 T3 DK1905775 T3 DK 1905775T3 DK 07291135 T DK07291135 T DK 07291135T DK 1905775 T3 DK1905775 T3 DK 1905775T3
Authority
DK
Denmark
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
receptor ligands
Prior art date
Application number
DK07291135.7T
Other languages
English (en)
Inventor
Jean-Louis Peglion
Christophe Poitevin
Mark Millan
Mauricette Brocco
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of DK1905775T3 publication Critical patent/DK1905775T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK07291135.7T 2006-09-26 2007-09-25 Tetracykliske forbindelser, fremgangsmåder til at fremstille disse, farmaceutiske sammensætninger indeholdende disse og anvendelse heraf som dopaminreceptorligander DK1905775T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0608413A FR2906249B1 (fr) 2006-09-26 2006-09-26 Composes tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK1905775T3 true DK1905775T3 (da) 2010-12-06

Family

ID=37877016

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07291135.7T DK1905775T3 (da) 2006-09-26 2007-09-25 Tetracykliske forbindelser, fremgangsmåder til at fremstille disse, farmaceutiske sammensætninger indeholdende disse og anvendelse heraf som dopaminreceptorligander

Country Status (32)

Country Link
US (1) US7470683B2 (da)
EP (1) EP1905775B1 (da)
JP (1) JP2008100995A (da)
KR (1) KR100934315B1 (da)
CN (1) CN101153043B (da)
AR (1) AR062950A1 (da)
AT (1) ATE480544T1 (da)
AU (1) AU2007219281A1 (da)
BR (1) BRPI0703655A2 (da)
CA (1) CA2603274C (da)
CY (1) CY1110799T1 (da)
DE (1) DE602007009004D1 (da)
DK (1) DK1905775T3 (da)
EA (1) EA013406B1 (da)
ES (1) ES2351945T3 (da)
FR (1) FR2906249B1 (da)
GE (1) GEP20104877B (da)
HK (1) HK1119163A1 (da)
HR (1) HRP20100605T1 (da)
MA (1) MA29371B1 (da)
MX (1) MX2007011524A (da)
MY (1) MY142517A (da)
NO (1) NO20074889L (da)
NZ (1) NZ561905A (da)
PL (1) PL1905775T3 (da)
PT (1) PT1905775E (da)
RS (1) RS51418B (da)
SG (1) SG141382A1 (da)
SI (1) SI1905775T1 (da)
UA (1) UA96125C2 (da)
WO (1) WO2008037888A2 (da)
ZA (1) ZA200708215B (da)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420480A (en) * 1981-11-20 1983-12-13 Merck & Co., Inc. Hexahydronaphth[1,2-b]-1,4-oxazines
CA1204745A (en) * 1981-11-20 1986-05-20 Merck Co. Hexahydronaphth (1,2-b) -1,4 -oxazines
FR2721027B1 (fr) 1994-06-08 1996-07-19 Adir Nouveaux dérivés tétracycliques de la 1,4-oxazine, leur procédé de préparation et les compositions pharmaceutiques les contenant.
FR2741074B1 (fr) * 1995-11-09 1997-12-19 Adir Nouveaux composes tetracycliques de la 1,4-oxazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2767825A1 (fr) * 1997-09-01 1999-02-26 Adir Nouvelles trans-3,4,4a,5,6,10b-hexahydro-2h-napht°1,2-b!-1, 4-oxazines disubstituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2845994B1 (fr) * 2002-10-18 2006-05-19 Servier Lab Nouveaux derives de benzo[e][1,4]oxazino[3,2-g]isoindole substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
HK1119163A1 (en) 2009-02-27
KR100934315B1 (ko) 2009-12-29
EA200701807A1 (ru) 2008-04-28
EP1905775A1 (fr) 2008-04-02
MX2007011524A (es) 2009-02-16
MY142517A (en) 2010-12-15
CN101153043B (zh) 2011-01-19
US7470683B2 (en) 2008-12-30
PT1905775E (pt) 2010-11-17
CY1110799T1 (el) 2015-06-10
EP1905775B1 (fr) 2010-09-08
CN101153043A (zh) 2008-04-02
SI1905775T1 (sl) 2010-10-29
AU2007219281A1 (en) 2008-04-10
FR2906249A1 (fr) 2008-03-28
SG141382A1 (en) 2008-04-28
RS51418B (en) 2011-02-28
BRPI0703655A2 (pt) 2009-05-19
US20080076765A1 (en) 2008-03-27
PL1905775T3 (pl) 2011-03-31
JP2008100995A (ja) 2008-05-01
EA013406B1 (ru) 2010-04-30
KR20080028316A (ko) 2008-03-31
NO20074889L (no) 2008-03-27
NZ561905A (en) 2009-01-31
CA2603274A1 (fr) 2008-03-26
ATE480544T1 (de) 2010-09-15
ES2351945T3 (es) 2011-02-14
WO2008037888A2 (fr) 2008-04-03
GEP20104877B (en) 2010-01-11
AR062950A1 (es) 2008-12-17
WO2008037888A3 (fr) 2008-06-12
FR2906249B1 (fr) 2008-12-19
DE602007009004D1 (de) 2010-10-21
UA96125C2 (ru) 2011-10-10
ZA200708215B (en) 2008-09-25
HRP20100605T1 (hr) 2010-12-31
MA29371B1 (fr) 2008-04-01
CA2603274C (fr) 2010-08-31

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