DK188077A - Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse - Google Patents

Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse

Info

Publication number
DK188077A
DK188077A DK188077A DK188077A DK188077A DK 188077 A DK188077 A DK 188077A DK 188077 A DK188077 A DK 188077A DK 188077 A DK188077 A DK 188077A DK 188077 A DK188077 A DK 188077A
Authority
DK
Denmark
Prior art keywords
callicraine
preparation
trypsin inhibitor
desamino
derivatives
Prior art date
Application number
DK188077A
Other languages
Danish (da)
English (en)
Inventor
E Schnabel
H D Schlumberger
G Reinhardt
E Truscheit
H Tschesche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK188077A publication Critical patent/DK188077A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • C07K14/8117Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/26Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK188077A 1976-04-30 1977-04-29 Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse DK188077A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762619246 DE2619246A1 (de) 1976-04-30 1976-04-30 Desamino-derivate des kallikrein- trypsin-inhibitors, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DK188077A true DK188077A (da) 1977-10-31

Family

ID=5976820

Family Applications (1)

Application Number Title Priority Date Filing Date
DK188077A DK188077A (da) 1976-04-30 1977-04-29 Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse

Country Status (11)

Country Link
US (1) US4118481A (de)
JP (1) JPS52134009A (de)
AT (1) AT361118B (de)
BE (1) BE854102A (de)
CH (1) CH635514A5 (de)
DE (1) DE2619246A1 (de)
DK (1) DK188077A (de)
FR (1) FR2349598A1 (de)
GB (1) GB1533358A (de)
NL (1) NL7704690A (de)
SE (1) SE442301B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748295A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti
DE2748294A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US5665216A (en) * 1986-10-21 1997-09-09 Northeastern University Capillary column for high performance electrophoretic separation and detection of SDS proteins and system and using the same
US4997537A (en) * 1986-10-21 1991-03-05 Northeastern University High performance microcapillary gel electrophoresis
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
JP3805785B2 (ja) * 1994-01-11 2006-08-09 ダイアックス コープ. カリクレイン阻害クニッツドメイン蛋白質およびその相同体
ES2375561T3 (es) * 1994-01-11 2012-03-02 Dyax Corporation Inhibidores de la plasmina humana derivados de dominios kunitz y �?cidos nucleicos que codifican los mismos.
US20040054082A1 (en) * 2001-12-03 2004-03-18 Bank David H Toughened polymer blends with improved surface properties
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
ES2559927T3 (es) * 2002-06-07 2016-02-16 Dyax Corp. Prevención y reducción de pérdida de sangre y respuesta inflamatoria
JP2005537006A (ja) 2002-08-28 2005-12-08 ダイアックス、コープ 臓器及び組織の保存方法
US7235530B2 (en) * 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en) 2005-12-30 2007-10-02 Dyax Corp. Prevention and reduction of blood loss
WO2007106746A2 (en) * 2006-03-10 2007-09-20 Dyax Corp. Formulations for ecallantide
CA2696208A1 (en) * 2007-08-21 2009-02-26 Genzyme Corporation Treatment with kallikrein inhibitors
JP2010536883A (ja) * 2007-08-23 2010-12-02 ジェンザイム・コーポレーション カリクレイン阻害剤を用いた治療
AU2010203712A1 (en) * 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
SI2521568T1 (sl) * 2010-01-06 2019-01-31 Dyax Corp. Proteini, ki vežejo plazemski kalikrein
CN103635489B (zh) 2011-01-06 2016-04-13 戴埃克斯有限公司 血浆前激肽释放酶结合蛋白
US10428158B2 (en) 2014-03-27 2019-10-01 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
EA201891388A1 (ru) 2015-12-11 2018-11-30 Дайэкс Корп. Ингибиторы калликреина плазмы и их применение для лечения обострения наследственного ангионевротического отека

Also Published As

Publication number Publication date
CH635514A5 (de) 1983-04-15
BE854102A (fr) 1977-10-31
US4118481A (en) 1978-10-03
ATA305477A (de) 1980-07-15
FR2349598B1 (de) 1980-02-22
AT361118B (de) 1981-02-25
SE7704928L (sv) 1977-10-31
GB1533358A (en) 1978-11-22
FR2349598A1 (fr) 1977-11-25
DE2619246A1 (de) 1977-11-10
SE442301B (sv) 1985-12-16
JPS52134009A (en) 1977-11-09
NL7704690A (nl) 1977-11-01

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Legal Events

Date Code Title Description
ATS Application withdrawn