DK1864129T3 - Doxurubicin-immunassay - Google Patents
Doxurubicin-immunassayInfo
- Publication number
- DK1864129T3 DK1864129T3 DK06739675.4T DK06739675T DK1864129T3 DK 1864129 T3 DK1864129 T3 DK 1864129T3 DK 06739675 T DK06739675 T DK 06739675T DK 1864129 T3 DK1864129 T3 DK 1864129T3
- Authority
- DK
- Denmark
- Prior art keywords
- doxorubicin
- immunoassay
- substituted
- immunoassays
- quantification
- Prior art date
Links
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 title abstract 5
- 229960004679 doxorubicin Drugs 0.000 title abstract 2
- 238000003018 immunoassay Methods 0.000 title abstract 2
- 239000013060 biological fluid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000011002 quantification Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9446—Antibacterials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/807—Hapten conjugated with peptide or protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66628805P | 2005-03-30 | 2005-03-30 | |
| PCT/US2006/011022 WO2006104970A1 (en) | 2005-03-30 | 2006-03-27 | Doxorubicin immunoassay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1864129T3 true DK1864129T3 (da) | 2010-11-29 |
Family
ID=37053697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06739675.4T DK1864129T3 (da) | 2005-03-30 | 2006-03-27 | Doxurubicin-immunassay |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US7569358B2 (enExample) |
| EP (2) | EP2239573A3 (enExample) |
| JP (1) | JP4896959B2 (enExample) |
| AT (1) | ATE476655T1 (enExample) |
| CA (1) | CA2602849C (enExample) |
| DE (1) | DE602006015929D1 (enExample) |
| DK (1) | DK1864129T3 (enExample) |
| ES (1) | ES2353212T3 (enExample) |
| WO (1) | WO2006104970A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2602849C (en) * | 2005-03-30 | 2013-06-04 | Saladax Biomedical Inc. | Doxorubicin immunoassay |
| US8076097B2 (en) * | 2009-08-19 | 2011-12-13 | Saladax Biomedical Inc. | Imatinib immunoassay |
| US20110165699A1 (en) * | 2009-12-08 | 2011-07-07 | Salamone Salvatore J | Irinotecan immunoassay |
| US20110136253A1 (en) * | 2009-12-08 | 2011-06-09 | Salamone Salvatore J | Irinotecan Immunoassay |
| US8114621B2 (en) * | 2010-03-12 | 2012-02-14 | Saladax Biomedical Inc. | Lenalidomide and thalidomide immunoassays |
| US8088594B2 (en) * | 2010-03-16 | 2012-01-03 | Saladax Biomedical Inc. | Risperidone immunoassay |
| WO2012067670A1 (en) * | 2010-11-18 | 2012-05-24 | Saladax Biomedical Inc. | Irinotecan immunoassay |
| US8426143B2 (en) | 2011-05-24 | 2013-04-23 | Saladax Biomedical Inc. | Gemcitabine immunoassay |
| US8771972B2 (en) * | 2011-05-24 | 2014-07-08 | Saladax Biomedical Inc. | Clozapine immunoassay |
| US20120301973A1 (en) * | 2011-05-24 | 2012-11-29 | Salamone Salvatore J | Clozapine immunoassay |
| WO2012167255A1 (en) * | 2011-06-03 | 2012-12-06 | The Regents Of The University Of Colorado, A Body Corporate | Anticancer prodrug therapies |
| US10782308B2 (en) | 2012-07-16 | 2020-09-22 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Direct reading detection kits for surface contamination by antineoplastic drugs |
| EP2922818B1 (en) | 2012-11-24 | 2018-09-05 | Hangzhou Dac Biotech Co., Ltd | Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules |
| AU2014384434B2 (en) | 2014-02-28 | 2016-11-03 | Hangzhou Dac Biotech Co., Ltd | Charged linkers and their uses for conjugation |
| WO2016026916A2 (en) * | 2014-08-19 | 2016-02-25 | Ecole Polytechnique Federale De Lausanne (Epfl) | Phase transfer based chemical sensing |
| NZ739830A (en) | 2015-07-12 | 2021-12-24 | Hangzhou Dac Biotech Co Ltd | Bridge linkers for conjugation of cell-binding molecules |
| US9839687B2 (en) | 2015-07-15 | 2017-12-12 | Suzhou M-Conj Biotech Co., Ltd. | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule |
| KR102345175B1 (ko) | 2016-11-14 | 2021-12-31 | 항저우 디에이씨 바이오테크 씨오, 엘티디 | 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용 |
| CN114149474B (zh) * | 2020-09-08 | 2024-03-19 | 鲁南制药集团股份有限公司 | 一种4’-表柔红霉素的中间体化合物及其制备方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3996344A (en) | 1972-05-15 | 1976-12-07 | Biological Developments, Inc. | Phenethylamine antigenic conjugates, their preparation, antibodies and use |
| US4016146A (en) | 1974-12-10 | 1977-04-05 | Biological Developments, Inc. | Phenethylamine antigenic conjugates, their preparation, antibodies, and use |
| US4269511A (en) | 1979-02-15 | 1981-05-26 | Abbott Laboratories | Apparatus and method for measuring the magnitude of polarization of light |
| US4420568A (en) | 1980-07-30 | 1983-12-13 | Abbott Laboratories | Fluorescent polarization immunoassay utilizing substituted triazinylaminofluoresceins |
| IT1223136B (it) * | 1987-11-17 | 1990-09-12 | Ist Naz Stud Cura Dei Tumori | Anticorpi monoclonali capaci di legarsi selettivamente alla doxorubicina ed analoghi e derivati |
| US4990443A (en) * | 1988-01-25 | 1991-02-05 | Boehringer Mannheim Gmbh | Hapten-protein conjugates and methods of use in immunoassays |
| IL106992A (en) | 1988-02-11 | 1994-06-24 | Bristol Myers Squibb Co | Acylhydrazone derivatives of anthracycline and methods for their preparation |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5101015A (en) | 1989-04-10 | 1992-03-31 | Abbott Laboratories | Reagents for an amphetamine-class fluorescence polarization immunoassay |
| IT1238675B (it) | 1990-01-26 | 1993-09-01 | Ist Naz Stud Cura Dei Tumori | Anticorpo monoclonale in grado di riconoscere uno specifico epitopo di glicosidi antraciclinici e ibridoma secernente tale anticorpo |
| US5622929A (en) * | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| CA2096495C (en) | 1992-06-16 | 2002-07-09 | Kathy Palmer Ordonez | Dual analyte immunoassay |
| US20020119095A1 (en) * | 1992-07-10 | 2002-08-29 | Reinhard Gabathuler | Chemotherapeutic agents conjugated to p97 and their methods of use in treating neurological tumours |
| AU670108B2 (en) * | 1992-09-11 | 1996-07-04 | Becton Dickinson & Company | Improved antibodies to plasmodium falciparum |
| DE4236237A1 (de) | 1992-10-27 | 1994-04-28 | Behringwerke Ag | Prodrugs, ihre Herstellung und Verwendung als Arzneimittel |
| AU1140495A (en) * | 1994-01-27 | 1995-08-03 | Bristol-Myers Squibb Company | Method for preparing thioether conjugates |
| DK0871490T3 (da) * | 1995-12-22 | 2003-07-07 | Bristol Myers Squibb Co | Forgrenede hydrazonlinkere |
| WO2002013843A2 (en) * | 2000-08-17 | 2002-02-21 | University Of British Columbia | Chemotherapeutic agents conjugated to p97 and their methods of use in treating neurological tumours |
| US7678551B2 (en) * | 2004-10-25 | 2010-03-16 | Seradyn, Inc. | Immunoassays for lamotrigine |
| CA2602849C (en) * | 2005-03-30 | 2013-06-04 | Saladax Biomedical Inc. | Doxorubicin immunoassay |
-
2006
- 2006-03-27 CA CA2602849A patent/CA2602849C/en not_active Expired - Fee Related
- 2006-03-27 EP EP20100007967 patent/EP2239573A3/en not_active Withdrawn
- 2006-03-27 ES ES06739675T patent/ES2353212T3/es active Active
- 2006-03-27 DK DK06739675.4T patent/DK1864129T3/da active
- 2006-03-27 US US11/389,934 patent/US7569358B2/en active Active
- 2006-03-27 JP JP2008504212A patent/JP4896959B2/ja not_active Expired - Fee Related
- 2006-03-27 AT AT06739675T patent/ATE476655T1/de not_active IP Right Cessation
- 2006-03-27 DE DE602006015929T patent/DE602006015929D1/de active Active
- 2006-03-27 EP EP06739675A patent/EP1864129B1/en not_active Not-in-force
- 2006-03-27 WO PCT/US2006/011022 patent/WO2006104970A1/en not_active Ceased
-
2009
- 2009-04-30 US US12/433,149 patent/US8084586B2/en not_active Expired - Fee Related
- 2009-04-30 US US12/433,111 patent/US8053205B2/en not_active Expired - Fee Related
-
2011
- 2011-09-23 US US13/242,124 patent/US20120015385A1/en not_active Abandoned
-
2012
- 2012-04-30 US US13/459,867 patent/US20120214184A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2239573A3 (en) | 2011-02-08 |
| JP2008537110A (ja) | 2008-09-11 |
| EP1864129A1 (en) | 2007-12-12 |
| US20120214184A1 (en) | 2012-08-23 |
| CA2602849A1 (en) | 2006-10-05 |
| JP4896959B2 (ja) | 2012-03-14 |
| US8053205B2 (en) | 2011-11-08 |
| US20090215078A1 (en) | 2009-08-27 |
| CA2602849C (en) | 2013-06-04 |
| EP2239573A2 (en) | 2010-10-13 |
| ES2353212T3 (es) | 2011-02-28 |
| EP1864129A4 (en) | 2009-02-18 |
| US20060223134A1 (en) | 2006-10-05 |
| DE602006015929D1 (de) | 2010-09-16 |
| US7569358B2 (en) | 2009-08-04 |
| EP1864129B1 (en) | 2010-08-04 |
| US20120015385A1 (en) | 2012-01-19 |
| ATE476655T1 (de) | 2010-08-15 |
| WO2006104970A1 (en) | 2006-10-05 |
| US20090215082A1 (en) | 2009-08-27 |
| US8084586B2 (en) | 2011-12-27 |
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