DK1861493T3 - Mutant allergen of the zwf gene (g6pdh) from coryne-shaped bacteria to increase lysine production - Google Patents
Mutant allergen of the zwf gene (g6pdh) from coryne-shaped bacteria to increase lysine productionInfo
- Publication number
- DK1861493T3 DK1861493T3 DK06725146.2T DK06725146T DK1861493T3 DK 1861493 T3 DK1861493 T3 DK 1861493T3 DK 06725146 T DK06725146 T DK 06725146T DK 1861493 T3 DK1861493 T3 DK 1861493T3
- Authority
- DK
- Denmark
- Prior art keywords
- coryne
- g6pdh
- lysine production
- shaped bacteria
- zwf gene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005013676A DE102005013676A1 (en) | 2005-03-24 | 2005-03-24 | Alleles of the zwf gene from coryneform bacteria |
PCT/EP2006/060519 WO2006100177A1 (en) | 2005-03-24 | 2006-03-07 | Mutant alleles of the zwf gene (g6pdh) from coryneform bacteria for increasing lysine production |
PCT/EP2006/060851 WO2006100211A1 (en) | 2005-03-24 | 2006-03-17 | Mutant alleles of the zwf gene (g6pdh) from coryneform bacteria for increasing lysine production |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1861493T3 true DK1861493T3 (en) | 2013-01-02 |
Family
ID=36370857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06725146.2T DK1861493T3 (en) | 2005-03-24 | 2006-03-17 | Mutant allergen of the zwf gene (g6pdh) from coryne-shaped bacteria to increase lysine production |
Country Status (4)
Country | Link |
---|---|
DE (1) | DE102005013676A1 (en) |
DK (1) | DK1861493T3 (en) |
ES (1) | ES2394918T3 (en) |
WO (2) | WO2006100177A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006026328A1 (en) * | 2006-06-02 | 2008-01-03 | Evonik Degussa Gmbh | Process for the preparation of a feed additive containing L-lysine |
DE102006032634A1 (en) | 2006-07-13 | 2008-01-17 | Evonik Degussa Gmbh | Process for the preparation of L-amino acids |
WO2008092956A1 (en) * | 2007-02-02 | 2008-08-07 | Evonik Degussa Gmbh | Production of l-lysine and l-lysine-containing feed additives |
DE102008001874A1 (en) | 2008-05-20 | 2009-11-26 | Evonik Degussa Gmbh | Process for the preparation of L-amino acids |
DE102009030342A1 (en) | 2009-06-25 | 2010-12-30 | Evonik Degussa Gmbh | Process for the fermentative production of organic chemical compounds |
DE102010003419B4 (en) | 2010-03-30 | 2019-09-12 | Evonik Degussa Gmbh | Process for the fermentative production of L-ornithine |
DE102011006716A1 (en) | 2011-04-04 | 2012-10-04 | Evonik Degussa Gmbh | Microorganism and process for the fermentative production of an organic chemical compound |
EP2762571A1 (en) | 2013-01-30 | 2014-08-06 | Evonik Industries AG | Microorganism and method for the production of amino acids by fermentation |
EP2940144A1 (en) | 2014-04-30 | 2015-11-04 | Evonik Degussa GmbH | Method for the production of l-lysine using an alkaliphilic bacterium |
CN112646767B (en) * | 2020-12-30 | 2022-08-09 | 宁夏伊品生物科技股份有限公司 | Strain with enhanced L-glutamic acid productivity and construction method and application thereof |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
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SU507634A1 (en) | 1973-09-24 | 1976-03-25 | Институт Микробиологии Имени А.Кирхенштейна Ан Латвийской Сср | Method for producing lysine |
JPS54105293A (en) | 1978-02-01 | 1979-08-18 | Ajinomoto Co Inc | Preparation of l-proline by fermentation |
JPS559783A (en) | 1978-07-10 | 1980-01-23 | Ajinomoto Co Inc | Preparation of l-lysine by fermentation |
US4601983A (en) | 1983-06-15 | 1986-07-22 | Ajinomoto Co., Inc. | Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-threonine and L-isoleucine |
JPH0655149B2 (en) | 1985-03-12 | 1994-07-27 | 協和醗酵工業株式会社 | Method for producing L-lysine |
US5250434A (en) | 1987-03-27 | 1993-10-05 | Ajinomoto Co., Inc. | Microorganisms for production of glutamic acid |
JP2656300B2 (en) | 1988-04-18 | 1997-09-24 | 協和醗酵工業株式会社 | Method for producing L-tryptophan |
GB2223754B (en) | 1988-09-12 | 1992-07-22 | Degussa | Dna encoding phosphoenolpyruvate carboxylase |
JP2990735B2 (en) | 1990-04-20 | 1999-12-13 | 味の素株式会社 | Fermentative production of L-lysine |
JP3023615B2 (en) | 1990-08-30 | 2000-03-21 | 協和醗酵工業株式会社 | Production method of L-tryptophan by fermentation method |
DE4100920A1 (en) | 1991-01-15 | 1992-07-16 | Degussa | ACTIVE SUBSTANCE PREPARATION FOR ORAL ADMINISTRATION TO Ruminants |
FR2679569B1 (en) | 1991-07-26 | 1995-05-19 | Eurolysine | PROCESS FOR SEPARATING LYSINE IN THE FORM OF AQUEOUS SOLUTIONS AND USE OF SUCH SOLUTIONS FOR ANIMAL FEEDING. |
DE4130868C2 (en) | 1991-09-17 | 1994-10-13 | Degussa | Animal feed supplement based on an amino acid and process for its preparation |
DE4130867A1 (en) | 1991-09-17 | 1993-03-18 | Degussa | PROCESS FOR THE FERMENTATIVE MANUFACTURE OF AMINO ACIDS |
JPH05195736A (en) | 1992-01-20 | 1993-08-03 | Mazda Motor Corp | Valve driving device of engine |
DE4232468A1 (en) | 1992-09-28 | 1994-03-31 | Consortium Elektrochem Ind | Microorganisms for the production of tryptophan and process for their production |
JP3369231B2 (en) | 1992-12-03 | 2003-01-20 | 協和醗酵工業株式会社 | Method for producing aromatic amino acids |
AU706285B2 (en) | 1995-05-16 | 1999-06-10 | Ajinomoto Co., Inc. | Feed additive |
DE19547361A1 (en) | 1995-12-19 | 1997-06-26 | Degussa | Process for the production of L-amino acids by fermentation |
DE19548222A1 (en) | 1995-12-22 | 1997-06-26 | Forschungszentrum Juelich Gmbh | Process for the microbial production of amino acids through increased activity of export carriers |
JPH09224661A (en) | 1996-02-23 | 1997-09-02 | Mitsubishi Chem Corp | Glucose-6-phosphate dehydrogenase and dna capable of coding the same |
JP4075087B2 (en) | 1996-12-05 | 2008-04-16 | 味の素株式会社 | Method for producing L-lysine |
DE19831609B4 (en) | 1997-10-04 | 2009-11-12 | Evonik Degussa Gmbh | Process for the preparation of amino acids of the aspartate and / or glutamate family and agents which can be used in the process |
JP2000262288A (en) | 1999-03-16 | 2000-09-26 | Ajinomoto Co Inc | Temperature-sensitive plasmid of coryneform bacterium |
CN1236690C (en) | 1999-06-23 | 2006-01-18 | 德古萨股份公司 | Water-containing animal feed additive with lysine and its producing method |
EP1257649B1 (en) | 1999-06-25 | 2010-01-20 | Paik Kwang Industrial Co., Ltd. | Corynebacterium glutamicum genes encoding metabolic pathway proteins |
WO2001000844A2 (en) | 1999-06-25 | 2001-01-04 | Basf Aktiengesellschaft | Corynebacterium glutamicum genes encoding proteins involved in carbon metabolism and energy production |
WO2001007626A2 (en) | 1999-07-23 | 2001-02-01 | Archer-Daniels-Midland Company | Methods for producing l-amino acids by increasing cellular nadph |
US6586214B1 (en) | 1999-09-15 | 2003-07-01 | Degussa Ag | Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene) |
DE19959328A1 (en) | 1999-12-09 | 2001-06-13 | Degussa | New nucleotide sequences coding for the zwa1 gene |
JP4623825B2 (en) | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | Novel polynucleotide |
US20030175911A1 (en) * | 2000-03-20 | 2003-09-18 | Stephen Hans | Process for the preparation of L-amino acids with amplification of the zwf gene |
WO2001070995A1 (en) | 2000-03-20 | 2001-09-27 | Degussa Ag | Process for the fermentative preparation of l-amino acids with amplification of the zwf gene |
DE60141633D1 (en) * | 2000-06-21 | 2010-05-06 | Kyowa Hakko Bio Co Ltd | NOVEL GLUCOSE-6-PHOSPHATE DEHYDROGENASE |
WO2002031158A2 (en) | 2000-10-13 | 2002-04-18 | Archer-Daniels-Midland Company | Feedback-resistant pyruvate carboxylase gene from corynebacterium |
DE10109996A1 (en) | 2001-03-01 | 2002-09-05 | Basf Ag | Process for changing the genome of gram-positive bacteria with a new conditionally negative dominant marker gene |
CN100554426C (en) | 2001-08-06 | 2009-10-28 | 德古萨股份公司 | Corynebacterium glutamicum with genetic modification produces L-Methionin |
US7160711B2 (en) | 2001-08-06 | 2007-01-09 | Degussa Ag | Coryneform bacteria which produce chemical compounds I |
CN100336901C (en) | 2001-08-06 | 2007-09-12 | 德古萨股份公司 | Coryneform bacteria which produce chemical compounds II |
DE10137815A1 (en) | 2001-08-06 | 2003-02-27 | Basf Ag | Process for the production of a marker-free mutant target organism and suitable plasmid vectors |
DE10155505A1 (en) * | 2001-11-13 | 2003-05-22 | Basf Ag | Genes that code for glucose-6-phosphate dehydrogenase proteins |
JP2003219807A (en) | 2002-01-25 | 2003-08-05 | Ajinomoto Co Inc | Granulated and dried product mainly comprising l-lysine |
US20040115304A1 (en) | 2002-12-16 | 2004-06-17 | Frank Dubner | Feesdstuffs additives containing L-lysine with improved abrasion resistance, and process for their production |
-
2005
- 2005-03-24 DE DE102005013676A patent/DE102005013676A1/en not_active Ceased
-
2006
- 2006-03-07 WO PCT/EP2006/060519 patent/WO2006100177A1/en not_active Application Discontinuation
- 2006-03-17 DK DK06725146.2T patent/DK1861493T3/en active
- 2006-03-17 ES ES06725146T patent/ES2394918T3/en active Active
- 2006-03-17 WO PCT/EP2006/060851 patent/WO2006100211A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE102005013676A1 (en) | 2006-09-28 |
ES2394918T3 (en) | 2013-02-06 |
WO2006100177A1 (en) | 2006-09-28 |
WO2006100211A1 (en) | 2006-09-28 |
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