DK183782A - Fremgangsmaade til fremstilling af rutin-nona-og-deca (h-)sulfalte - Google Patents

Fremgangsmaade til fremstilling af rutin-nona-og-deca (h-)sulfalte Download PDF

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Publication number
DK183782A
DK183782A DK183782A DK183782A DK183782A DK 183782 A DK183782 A DK 183782A DK 183782 A DK183782 A DK 183782A DK 183782 A DK183782 A DK 183782A DK 183782 A DK183782 A DK 183782A
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DK
Denmark
Prior art keywords
nona
deca
sulfalte
procedure
rutin
Prior art date
Application number
DK183782A
Other languages
English (en)
Inventor
V G Nair
S Bernstein
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DK183782A publication Critical patent/DK183782A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/07—Benzo[b]pyran-4-ones

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Description

hvor R er hydrogen eller -SO^A, hvert X er -SO^A, og A er en farmaceutisk acceptabel kation, fremstilles ved omsætning af enten rutin(nona til octa)(H)sulfater eller rutin(mono til no-na)(H)sulfater med triethylamin-svovltrioxid, isolering fra aminholdig acetone og behandling med vandig kation. Disse rutin--nona- og deca(H-)sulfatsalte har i ren form uventet stor in vi-tro-virkning som komplementinhibitorer.
DK183782A 1980-08-25 1982-04-23 Fremgangsmaade til fremstilling af rutin-nona-og-deca (h-)sulfalte DK183782A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/181,251 US4334058A (en) 1979-07-31 1980-08-25 Rutin poly(H--)sulfate salts and related compounds
US18125180 1980-08-25
US8101123 1981-08-21
PCT/US1981/001123 WO1982000586A1 (en) 1980-08-25 1981-08-21 Novel rutin nona-and deca(h-)sulfate salts,methods of preparing novel salts,and use of novel salts as complement inhibitors

Publications (1)

Publication Number Publication Date
DK183782A true DK183782A (da) 1982-04-23

Family

ID=22663490

Family Applications (1)

Application Number Title Priority Date Filing Date
DK183782A DK183782A (da) 1980-08-25 1982-04-23 Fremgangsmaade til fremstilling af rutin-nona-og-deca (h-)sulfalte

Country Status (10)

Country Link
US (1) US4334058A (da)
EP (1) EP0058697A4 (da)
JP (1) JPS57501235A (da)
KR (1) KR830006324A (da)
DK (1) DK183782A (da)
ES (1) ES504948A0 (da)
PL (1) PL232802A1 (da)
WO (1) WO1982000586A1 (da)
YU (1) YU206581A (da)
ZA (1) ZA815883B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399126A (en) * 1982-04-16 1983-08-16 American Cyanamid Company Modulators of the complement system
US4404195A (en) * 1982-04-16 1983-09-13 American Cyanamid Company Poly cation salts of monohexosethio (or oxy) alkyl diamides
US4393055A (en) * 1982-05-03 1983-07-12 American Cyanamid Company Hydroxyalkyl ether derivatives of rutin poly(H-)sulfate and method of use
US4402944A (en) * 1982-06-01 1983-09-06 American Cyanamid Company Polysulfonate Sennoside A & B compounds and method of use
ES8707969A1 (es) * 1986-05-09 1987-10-01 Espanola Prod Quimicos Procedimiento de preparacion de una mezcla estandar de o-(b-hidroxietil)-diosminas
US5981163A (en) * 1990-05-15 1999-11-09 New York Blood Center, Inc. Process for the sterilization of biological compositions using irradiation and quenchers of type I and type II photodynamic reactions
ES2041216B1 (es) * 1992-02-25 1994-06-16 Espanola Prod Quimicos Procedimiento de preparacion de un nuevo derivado sulfatado de diosmina.
EP0888369A1 (en) * 1996-02-21 1999-01-07 Glycomed Incorporated Sialyl lewis x mimetics containing flavanoid backbones
DE102006017879A1 (de) * 2006-04-13 2007-10-25 Merck Patent Gmbh Verwendung von Flavonoiden
CN102643886A (zh) * 2012-04-13 2012-08-22 东华大学 一种利用漆酶介体体系催化制备聚合芦丁的方法
CN103145781B (zh) * 2013-01-14 2016-03-16 李玉山 一种抗艾滋病化合物芦丁磺酸钠的合成工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT320869B (de) * 1972-12-08 1975-03-10 Trommsdorff Fa H Verfahren zur Herstellung eines neuen Flavanonderivates
US4066829A (en) * 1976-07-12 1978-01-03 American Cyanamid Company Malto-dextrin poly(H-)sulfates
US4021545A (en) * 1976-07-12 1977-05-03 American Cyanamid Company Complement inhibitors
US4238483A (en) * 1979-07-19 1980-12-09 Frazier Stephen E Antimicrobial compositions of matter and a process for preparing antimicrobial compositions of matter from naturally occurring flavanoid glycosides
US4258034A (en) * 1979-11-05 1981-03-24 American Cyanamid Company Lactobionic acid poly(H-sulfate) and salts thereof useful as complement inhibitors

Also Published As

Publication number Publication date
EP0058697A1 (en) 1982-09-01
ZA815883B (en) 1982-09-29
YU206581A (en) 1983-06-30
ES8207191A2 (es) 1982-10-01
WO1982000586A1 (en) 1982-03-04
ES504948A0 (es) 1982-10-01
PL232802A1 (da) 1982-11-08
KR830006324A (ko) 1983-09-20
EP0058697A4 (en) 1983-01-14
US4334058A (en) 1982-06-08
JPS57501235A (da) 1982-07-15

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AHB Application shelved due to non-payment