DK180288A - 5-SUBSTITUTED QUINOLON AND NAPHTHYRIDONCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE - Google Patents
5-SUBSTITUTED QUINOLON AND NAPHTHYRIDONCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USEInfo
- Publication number
- DK180288A DK180288A DK180288A DK180288A DK180288A DK 180288 A DK180288 A DK 180288A DK 180288 A DK180288 A DK 180288A DK 180288 A DK180288 A DK 180288A DK 180288 A DK180288 A DK 180288A
- Authority
- DK
- Denmark
- Prior art keywords
- quinolon
- substituted
- preparation
- acid derivatives
- naphthyridoncarboxylic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19873711193 DE3711193A1 (en) | 1987-04-02 | 1987-04-02 | 5-SUBSTITUTED CHINOLON AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES |
Publications (2)
Publication Number | Publication Date |
---|---|
DK180288D0 DK180288D0 (en) | 1988-03-30 |
DK180288A true DK180288A (en) | 1988-10-03 |
Family
ID=6324762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK180288A DK180288A (en) | 1987-04-02 | 1988-03-30 | 5-SUBSTITUTED QUINOLON AND NAPHTHYRIDONCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0284935A1 (en) |
JP (1) | JPS63258855A (en) |
KR (1) | KR880012593A (en) |
CN (1) | CN88101741A (en) |
AU (1) | AU1381188A (en) |
DD (1) | DD274029A5 (en) |
DE (1) | DE3711193A1 (en) |
DK (1) | DK180288A (en) |
FI (1) | FI881501A (en) |
HU (1) | HU201050B (en) |
IL (1) | IL85943A0 (en) |
NO (1) | NO881121L (en) |
PT (1) | PT87124B (en) |
ZA (1) | ZA882318B (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5563138A (en) * | 1987-04-16 | 1996-10-08 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
JPS649992A (en) * | 1987-06-30 | 1989-01-13 | Dainippon Pharmaceutical Co | 1,8-crosslinked quinolincarboxylic acid derivative, ester thereof and salt thereof |
US4839355A (en) * | 1987-09-09 | 1989-06-13 | Sterling Drug Inc. | Tricyclic-pyridinylquinoline compounds, their preparation and use |
US5164392A (en) * | 1987-10-16 | 1992-11-17 | Dainippon Pharmaceutical Co., Ltd. | Quinoline derivatives and antibacterial agent containing them |
IL88003A (en) * | 1987-10-16 | 1992-11-15 | Dainippon Pharmaceutical Co | Quinoline derivatives,their preparation and pharmaceutical compositions containing them |
JPH0228178A (en) * | 1988-04-23 | 1990-01-30 | Toyama Chem Co Ltd | Novel pyridonecarboxylic acid derivative and salt thereof |
AU609974B2 (en) * | 1988-05-18 | 1991-05-09 | Warner-Lambert Company | Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids |
JPH0674261B2 (en) * | 1988-06-21 | 1994-09-21 | 塩野義製薬株式会社 | Quinolonecarboxylic acid derivative |
FI901201A0 (en) * | 1989-03-13 | 1990-03-09 | Bristol Myers Squibb Co | ANTIBAKTERIELLA 5-SUBSTITUERADE 1,4-DIHYDRO-4-OXONAFTYRIDIN-3-CARBOXYLATDERIVAT OCH DERAS FRAMSTAELLNING. |
JPH04504852A (en) * | 1989-04-26 | 1992-08-27 | ジ・アップジョン・カンパニー | Antibacterial pyrido(1,2,3-de)-1,4-benzoxazinone agent |
WO1991004972A1 (en) * | 1989-10-06 | 1991-04-18 | Pfizer Inc. | 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents |
US5385913A (en) * | 1989-10-06 | 1995-01-31 | Pfizer Inc. | 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents |
ATE193890T1 (en) | 1990-04-18 | 2000-06-15 | Procter & Gamble Pharma | ANTIMICROBIAL QUINOLONYL LACTAMES |
DE4032560A1 (en) * | 1990-10-13 | 1992-04-16 | Bayer Ag | 7- (2,7-DIAZABICYCLO (3.3.0) OCTYL) -3-CHINOLON AND -NAPHTYRIDONCARBONIC ACID DERIVATIVES |
FR2681863B1 (en) * | 1991-09-27 | 1995-02-03 | Rhone Dpc Europ | SOLUTION OF SPARFLOXACIN, ITS PREPARATION AND SALT CONSTITUTING IT. |
WO1993013101A1 (en) * | 1991-12-27 | 1993-07-08 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridonecarboxylate compound, pharmaceutical use thereof, and spiro compound |
US5646163A (en) * | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
TW252107B (en) * | 1993-08-27 | 1995-07-21 | Hokuriku Pharmacetical Co Ltd | |
CN1183778A (en) * | 1995-01-24 | 1998-06-03 | 北陆制药株式会社 | Quinolinecarboxylic acid derivs. |
DE10108750A1 (en) * | 2001-02-23 | 2002-09-05 | Bayer Ag | Improved process for the production of fluoroquinolonecarboxylic acids |
JP2006504690A (en) | 2002-09-10 | 2006-02-09 | ファイザー・プロダクツ・インク | Diazabicyclic compounds useful for the treatment of CNS and other disorders |
CN100410249C (en) | 2003-09-10 | 2008-08-13 | 杏林制药株式会社 | 7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) Q uinolonecarboxylic acid derivative |
EP1732541A4 (en) | 2004-04-07 | 2008-03-05 | Takeda Pharmaceutical | Cyclic compounds |
US8222407B2 (en) | 2007-05-24 | 2012-07-17 | Kyorin Pharmaceutical Co., Ltd. | Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position |
CN105037388A (en) * | 2015-08-28 | 2015-11-11 | 安徽环球药业股份有限公司 | Preparing method for antofloxacin |
CN109251211A (en) * | 2016-12-21 | 2019-01-22 | 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) | A kind of quinolonecarboxylic acid compound and its intermediate, preparation method and application |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59137482A (en) * | 1983-01-26 | 1984-08-07 | Otsuka Pharmaceut Co Ltd | Pyrrolo(3,2,1,-ij)quinoline-5-carboxylic acid derivative |
IE58742B1 (en) * | 1984-07-20 | 1993-11-05 | Warner Lambert Co | Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds |
US4657913A (en) * | 1985-04-18 | 1987-04-14 | Warner-Lambert Company | Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents |
AU594983B2 (en) * | 1985-10-29 | 1990-03-22 | Dainippon Pharmaceutical Co. Ltd. | Novel quinoline derivatives and processes for preparation thereof |
US4977154A (en) * | 1985-12-12 | 1990-12-11 | Warner-Lambert Company | 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents |
EP0242789A3 (en) * | 1986-04-25 | 1990-09-05 | Dainippon Pharmaceutical Co., Ltd. | Novel quinoline derivates and processes for preparation thereof |
-
1987
- 1987-04-02 DE DE19873711193 patent/DE3711193A1/en not_active Withdrawn
-
1988
- 1988-03-14 NO NO881121A patent/NO881121L/en unknown
- 1988-03-21 EP EP88104452A patent/EP0284935A1/en not_active Withdrawn
- 1988-03-28 AU AU13811/88A patent/AU1381188A/en not_active Abandoned
- 1988-03-29 DD DD88314159A patent/DD274029A5/en not_active IP Right Cessation
- 1988-03-30 DK DK180288A patent/DK180288A/en not_active Application Discontinuation
- 1988-03-30 FI FI881501A patent/FI881501A/en not_active Application Discontinuation
- 1988-03-30 PT PT87124A patent/PT87124B/en not_active IP Right Cessation
- 1988-03-31 ZA ZA882318A patent/ZA882318B/en unknown
- 1988-03-31 CN CN198888101741A patent/CN88101741A/en active Pending
- 1988-03-31 KR KR1019880003588A patent/KR880012593A/en not_active Application Discontinuation
- 1988-03-31 IL IL85943A patent/IL85943A0/en unknown
- 1988-04-01 JP JP63078298A patent/JPS63258855A/en active Pending
- 1988-04-01 HU HU881619A patent/HU201050B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ZA882318B (en) | 1988-10-04 |
DD274029A5 (en) | 1989-12-06 |
FI881501A (en) | 1988-10-03 |
JPS63258855A (en) | 1988-10-26 |
PT87124B (en) | 1992-07-31 |
KR880012593A (en) | 1988-11-28 |
PT87124A (en) | 1988-04-01 |
IL85943A0 (en) | 1988-09-30 |
DE3711193A1 (en) | 1988-10-13 |
EP0284935A1 (en) | 1988-10-05 |
NO881121D0 (en) | 1988-03-14 |
HU201050B (en) | 1990-09-28 |
AU1381188A (en) | 1988-10-06 |
CN88101741A (en) | 1988-11-16 |
FI881501A0 (en) | 1988-03-30 |
HUT47098A (en) | 1989-01-30 |
DK180288D0 (en) | 1988-03-30 |
NO881121L (en) | 1988-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ATS | Application withdrawn |