FI881501A - 5-SUBSTITUERADE KINOLON- OCH NAFTYRIDONKARBOXYLSYRADERIVAT. - Google Patents

5-SUBSTITUERADE KINOLON- OCH NAFTYRIDONKARBOXYLSYRADERIVAT. Download PDF

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Publication number
FI881501A
FI881501A FI881501A FI881501A FI881501A FI 881501 A FI881501 A FI 881501A FI 881501 A FI881501 A FI 881501A FI 881501 A FI881501 A FI 881501A FI 881501 A FI881501 A FI 881501A
Authority
FI
Finland
Prior art keywords
naftyridonkarboxylsyraderivat
kinolon
substituerade
och
substituerade kinolon
Prior art date
Application number
FI881501A
Other languages
Finnish (fi)
Other versions
FI881501A0 (en
Inventor
Uwe Petersen
Klaus Grohe
Michael Schriewer
Thomas Schenke
Ingo Haller
Karl Georg Metzger
Rainer Endermann
Hans-Joachim Zeiler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of FI881501A0 publication Critical patent/FI881501A0/en
Publication of FI881501A publication Critical patent/FI881501A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
FI881501A 1987-04-02 1988-03-30 5-SUBSTITUERADE KINOLON- OCH NAFTYRIDONKARBOXYLSYRADERIVAT. FI881501A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873711193 DE3711193A1 (en) 1987-04-02 1987-04-02 5-SUBSTITUTED CHINOLON AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES

Publications (2)

Publication Number Publication Date
FI881501A0 FI881501A0 (en) 1988-03-30
FI881501A true FI881501A (en) 1988-10-03

Family

ID=6324762

Family Applications (1)

Application Number Title Priority Date Filing Date
FI881501A FI881501A (en) 1987-04-02 1988-03-30 5-SUBSTITUERADE KINOLON- OCH NAFTYRIDONKARBOXYLSYRADERIVAT.

Country Status (14)

Country Link
EP (1) EP0284935A1 (en)
JP (1) JPS63258855A (en)
KR (1) KR880012593A (en)
CN (1) CN88101741A (en)
AU (1) AU1381188A (en)
DD (1) DD274029A5 (en)
DE (1) DE3711193A1 (en)
DK (1) DK180288A (en)
FI (1) FI881501A (en)
HU (1) HU201050B (en)
IL (1) IL85943A0 (en)
NO (1) NO881121L (en)
PT (1) PT87124B (en)
ZA (1) ZA882318B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
JPS649992A (en) * 1987-06-30 1989-01-13 Dainippon Pharmaceutical Co 1,8-crosslinked quinolincarboxylic acid derivative, ester thereof and salt thereof
US4839355A (en) * 1987-09-09 1989-06-13 Sterling Drug Inc. Tricyclic-pyridinylquinoline compounds, their preparation and use
IL88003A (en) * 1987-10-16 1992-11-15 Dainippon Pharmaceutical Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
US5164392A (en) * 1987-10-16 1992-11-17 Dainippon Pharmaceutical Co., Ltd. Quinoline derivatives and antibacterial agent containing them
JPH0228178A (en) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd Novel pyridonecarboxylic acid derivative and salt thereof
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
JPH0674261B2 (en) * 1988-06-21 1994-09-21 塩野義製薬株式会社 Quinolonecarboxylic acid derivative
AU5123690A (en) * 1989-03-13 1990-09-13 Bristol-Myers Squibb Company 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents
AU5404790A (en) * 1989-04-26 1990-11-16 Upjohn Company, The Antibacterial pyrido(1,2,3-de)-1,4-benzoxazinone agents
US5385913A (en) * 1989-10-06 1995-01-31 Pfizer Inc. 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents
WO1991004972A1 (en) * 1989-10-06 1991-04-18 Pfizer Inc. 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents
ES2147721T3 (en) 1990-04-18 2000-10-01 Procter & Gamble Pharma QUINOLONYL ANTIMICROBIAL LACTAMS.
DE4032560A1 (en) * 1990-10-13 1992-04-16 Bayer Ag 7- (2,7-DIAZABICYCLO (3.3.0) OCTYL) -3-CHINOLON AND -NAPHTYRIDONCARBONIC ACID DERIVATIVES
FR2681863B1 (en) * 1991-09-27 1995-02-03 Rhone Dpc Europ SOLUTION OF SPARFLOXACIN, ITS PREPARATION AND SALT CONSTITUTING IT.
WO1993013101A1 (en) * 1991-12-27 1993-07-08 Yoshitomi Pharmaceutical Industries, Ltd. Pyridonecarboxylate compound, pharmaceutical use thereof, and spiro compound
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
TW252107B (en) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
WO1996022988A1 (en) * 1995-01-24 1996-08-01 Hokuriku Seiyaku Co., Ltd. Quinolinecarboxylic acid derivatives
DE10108750A1 (en) * 2001-02-23 2002-09-05 Bayer Ag Improved process for the production of fluoroquinolonecarboxylic acids
JP2006504690A (en) * 2002-09-10 2006-02-09 ファイザー・プロダクツ・インク Diazabicyclic compounds useful for the treatment of CNS and other disorders
JP4639149B2 (en) 2003-09-10 2011-02-23 杏林製薬株式会社 7- (4-Substituted-3-cyclopropylaminomethyl-1-pyrrolidinyl) quinolonecarboxylic acid derivatives
WO2005099688A2 (en) 2004-04-07 2005-10-27 Takeda Pharmaceutical Company Limited Cyclic compounds
WO2008143343A1 (en) 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
CN105037388A (en) * 2015-08-28 2015-11-11 安徽环球药业股份有限公司 Preparing method for antofloxacin
CN109251211A (en) * 2016-12-21 2019-01-22 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) A kind of quinolonecarboxylic acid compound and its intermediate, preparation method and application

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59137482A (en) * 1983-01-26 1984-08-07 Otsuka Pharmaceut Co Ltd Pyrrolo(3,2,1,-ij)quinoline-5-carboxylic acid derivative
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
EP0242789A3 (en) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivates and processes for preparation thereof

Also Published As

Publication number Publication date
KR880012593A (en) 1988-11-28
DD274029A5 (en) 1989-12-06
NO881121D0 (en) 1988-03-14
HUT47098A (en) 1989-01-30
HU201050B (en) 1990-09-28
DE3711193A1 (en) 1988-10-13
PT87124A (en) 1988-04-01
AU1381188A (en) 1988-10-06
DK180288D0 (en) 1988-03-30
FI881501A0 (en) 1988-03-30
IL85943A0 (en) 1988-09-30
ZA882318B (en) 1988-10-04
EP0284935A1 (en) 1988-10-05
JPS63258855A (en) 1988-10-26
NO881121L (en) 1988-10-03
PT87124B (en) 1992-07-31
CN88101741A (en) 1988-11-16
DK180288A (en) 1988-10-03

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