DK180059B1 - Eco-friendly long-term protection compositions and uses - Google Patents

Eco-friendly long-term protection compositions and uses Download PDF

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Publication number
DK180059B1
DK180059B1 DKPA201800907A DKPA201800907A DK180059B1 DK 180059 B1 DK180059 B1 DK 180059B1 DK PA201800907 A DKPA201800907 A DK PA201800907A DK PA201800907 A DKPA201800907 A DK PA201800907A DK 180059 B1 DK180059 B1 DK 180059B1
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preparation
composition
cleaner
care
lactic acid
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DKPA201800907A
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Danish (da)
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Schmidt Hansen Lars
James Lüscher Christopher
Wagner Daria
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ACT.Global A/S
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Priority to DKPA201800907A priority Critical patent/DK180059B1/en
Priority to PCT/DK2019/050364 priority patent/WO2020103997A1/en
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L79/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen or carbon only, not provided for in groups C08L61/00 - C08L77/00
    • C08L79/02—Polyamines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/04—Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0206—Polyalkylene(poly)amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/17—Combination with washing or cleaning means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/25—Rooms in buildings, passenger compartments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/26—Textiles, e.g. towels, beds, cloths

Abstract

Disclosed are compositions comprising a) an antimicrobial agent, which is selected from the group consisting of lactic acids, comprising L(+) optical isomer of lactic acid or a racemic lactic acid, and b) a polyamine, especially a polyethylenimine. The polyamine is effective as a booster for the antimicrobial properties of lactic acid isomers and their mixtures. Compositions can further comprise c) a tensid, and d) a primer for tensid, resulting in better distribution of tensid in the bulk composition, a synergetic effect of b), c) and d) on the biocidal properties of a) is achieved, allowing for a long-term synergetic biocidal effect of our eco-friendly solution at very low biocide concentration. The uses of the disclosed compositions for manufacturing of various biocidal formulations and as various biocidal formulations are claimed.

Description

TECHNICAL FIELD
The present invention relates to biocidal compositions comprising an L-lactic acid isomer or racemic lactic acid as an antimicrobial agent in combination with a polyethyleneimine. The effect of polyethyleneimine as a booster for biocidal properties of said antimicrobial agent can be further improved by a tensid and a stabilising agent (primer) for the tensid.
BACKGROUND
US 2016/0262382 A1 by LAN, T. et al describes a disinfectant formulation comprising two biocidal compounds, lactic acid and the polymeric compound, which may be polyethyleneimine when several selections for possible groups are made according to their formula. Both compounds can be present in amounts of 0.05% to 10% b.w. It is mentioned that weak acids such as lactic acid as biocidal compound have been shown to be particularly effective in bathroom cleaners. The formulation further comprises a surfactant in an amount of 0.01% to 10% b.w. However, US 2016/0262382 A1 does not disclose any specific embodiments directed towards compositions comprising only one biocide, being selected from racemic or L-lactic acid. It provides no hints to select the specific combination of lactic acid and polyethyleneimine.
WO13124784 A1 by PURSCHWITZ et al. discloses composition comprising a) a biocidal agent, which is selected from the group consisting of biocides containing halogen atoms and/or containing phenolic moieties, formic acid, chlorine dioxide, chlorine dioxide generating compounds, dialdehydes; components containing a biocidal metal such as silver, and b) a polyethyleneimine. The polyethyleneimine is effective as a booster for the biocidal agent. Though lactic acid and its salts is mentioned in description part of WO13124784 in a big bulk group of possible biocides, and also listed under further additives, improving the biocidal effect of the biocide, and even as an antioxidant example later on, there is no mentioning in WO13124784, that especially one of the two optical isomers or a racemic lactic acid would perform better than the other isomer, and lactic acid is not claimed as a biocide, either. Our selection invention discloses that by using the specific isomer of lactic acid or a racemic lactic acid as a biocide, a long-lasting and eco-friendly protective effect can be achieved using much lower concentration of biocide than claimed by WO13124784. The use of a surfactant is disclosed by WO13124784. However, we disclose that by using a tensid for stabilising polyethyleneimine, and by using a further additive (a tensid primer) ensuring a better distribution of the tensid in the composition, a surprising synergetic effect is achieved, boosting the biocidal properties of our specifically selected biocide.
Other examples of polyamines for boosting biocide properties, suitable for our inventive compositions, can be these disclosed by SCHONEMYR et al in US2007042198, US2008286225 and IN04627DN2007, all disclosing polyamines, having polyethyleneimine precursors with various structural and functional modifications.
SUMMARY
Throughout this disclosure, the term an antimicrobial agent is interchangeable with its scientific and regulatory synonyms comprising: a pesticide (in USA), a biocide, a disinfectant.
In a first aspect, a composition is claimed, comprising only one specifically selected antimicrobial agent a) being L-lactic acid isomer or racemic lactic acid, in amount of up to lwt.% of total weight of the composition, and a polyethyleneimine compound b) in amount of up to 0.lwt.% of total weight of the composition, providing a long-lasting biocidal effect at environment-friendly concentrations.
In a second aspect, the biocidal effect can be further enhanced and prolonged by using a tensid and a primer, where tensid stabilizes the polyethyleneimine compound, and said primer ensures an even distribution of the tensid in the composition. The use of a polyethyleneimine compound b), a tensid c) and a primer d), individually or in any combination for promoting the biocidal effect of our selected antimicrobial agent a), being an L-lactic acid isomer or racemic lactic acid, is claimed. The collective use of a polyethyleneimine compound b), a tensid c) and a primer d) provides a synergetic enhancing of biocidal properties of our specific antimicrobial agent a), allowing for a reduction of the antimicrobial agent concentration needed for satisfactory disinfection levels.
In a third aspect of the invention, the use of the compositions according to the first aspect of invention for manufacturing of various products is claimed, such as, for the manufacture of home care formulation, such as a biocide, disinfectant, all-purpose cleaner, laundry detergent, dishwashing liquid, deodorant, fabric conditioner, product for disinfection and sanitization of hard surfaces, floor cleaner, glass cleaner, kitchen cleaner, bath cleaner, sanitary cleaner, hygiene rinse product for fabrics, carpet cleaner, furniture cleaner, or a product for conditioning, sealing, caring or treating hard and soft surfaces; or for the manufacture of a personal care formulation, especially a deodorant, skin care preparation, bath preparation, cosmetic care preparation, foot-care preparation, light-protective preparation, skin-tanning preparation, depigmenting preparation, insect-repellent, antiperspirant, preparation for cleansing and caring for blemished skin, hair-removal preparation, shaving preparation, fragrance preparation, cosmetic hair-treatment preparation, antidandruff preparation, oral care composition.
In a forth aspect of the invention, the use of the compositions according to the first aspect of invention as various products is claimed, such as home care formulation, such as a biocide, disinfectant, all-purpose cleaner, laundry detergent, dishwashing liquid, deodorant, fabric conditioner, product for disinfection and sanitization of hard surfaces, floor cleaner, glass cleaner, kitchen cleaner, bath cleaner, sanitary cleaner, hygiene rinse product for fabrics, carpet cleaner, furniture cleaner, or a product for conditioning, sealing, caring or treating hard and soft surfaces; or for the manufacture of a personal care formulation, especially a deodorant, skin care preparation, bath preparation, cosmetic care preparation, foot-care preparation, light-protective preparation, skin-tanning preparation, depigmenting preparation, insect-repellent, anti- perspirant, preparation for cleansing and caring for blemished skin, hair-removal preparation, shaving preparation, fragrance preparation, cosmetic hair-treatment preparation, antidandruff preparation, oral care composition.
DETAILED DISCLOSURE
In one aspect, a composition comprising of only one antimicrobial agent a) being L-lactic acid isomer or racemic lactic acid and b) being a polyethyleneimine of molecular weight higher than 400 g/mol, and preferably has a number-average molecular weight in the range from 500 to 2 000 000 g/mol, especially 750 g/mol to 100 000 g/mol, said polyethyleneimine is a homopolymer, or an oligomer or polymer grafted with 0.01 to 100 parts by weight of ethylene oxide on 1 part by weight of the polyethyleneimine, most preferably, the polyethyleneimine is a branched polyethyleneimine homopolymer, whose uncharged form conforms to the empirical formula -(CH2-CH2-NH)n- wherein n ranges from approximately 10 to 100000, or is a grafted variant thereof, shows very good performance. A test based on the European standardized test for Chemical disinfectants and antiseptics was conducted, namely, Quantitative suspension test for the evaluation of bactericidal activity in the medical area- (DS/EN 13727:2012+A2:2015). In this test, 8ml of solution is taken and mixed with a premix of 1ml of test organisms and 1 ml of interfering solution. After the addition, the mixture was shortly mixed on a vortex mixer and is left until the contact time being tested has passed. After contact time, 1 ml of the mixture is transferred to a solution comprising 8 ml neutralizer and 1 ml of water, and vortexed again. After 5 mins of neutralization, samples are taken from the mixture and diluted to 10-5 and 10-6 and added to a petri dish (size 90100 mm). These petri dishes are incubated for 20-24 hours at 36-37 degrees Celsius, and the colony forming units are counted, afterwards, the plates are incubated for another 20-24 hours, and the colony forming units are recounted. If the number of colonies has increased, the higher number will be used.
Our tests showed that the compositions comprising a) and b) especially being the two PEI products A-200 by Appeartex AB and Lupasol FG by BASF, showed up to full reduction (100wt.%) of test organisms at concentrations of a) below 1wt.% and a contact time of 1 min. The compound a) alone showed a lower efficacy of log1.3 (96.55wt.% reduction) at a concentration of 1wt.% and a contact time of 1 min. At a contact time of 5 min the mixture of a) and b) specifically A-200 by Appeartex AB showed a log7 or higher reduction at dilutions of 1:10 of the original test. Compound a) alone at 3wt.% concentration and a contact time of 5 mins achieved a log7 or higher reduction, but only without dilution.
The interaction of a) and b) is considered to give a synergetic effect that amplifies to biocidal activity of a). Compound b) is a cationic polymer and affects the composition by being an attachment promoter, first of this means that a) will lay close and attach with b). Further, because of the attachment promotion the outer surfaces of cells will attract to b) and therefore b) will facilitate strong attachment to microorganisms, allowing a) to effectively kill them.
In second aspect, compound c) stabilises the formulation of a) and b) and upholds a uniform distribution of a) and b). It further lowers the surface tension of the composition, allowing for a higher contact area between a), b) and the surfaces. Compound d) gives a synergetic effect with c) which leads to an improved product it has a positive effect on the rheology of c) in the composition which leads to an even better distribution in the composition. Further, d) leads to a dermatological improvement of the composition and has a positive effect on the foam building of c). When the composition is applied to a surface, an even distribution of a) and b) through c) and d) assures that a) and b) is distributed evenly over the whole surface and doesn't accumulate in clusters. Compound b) binds a) to the target surface and allows for the release of a) when needed. When applied to a surface, b) creates a strong bond to almost any type of surface, even surfaces that are normally difficult to adhere to, including certain plastic types or inorganic materials, such as glass and tiles. The strong bond makes the product stick to the surface, even when the surface is subjected to a mechanical stress, e.g. rinsing with water. A range of test where done where the composition solutions was applied to a stainless steel surface and left for a set amount of time between 3 hours and 14 days. After the set time has passed, a known amount of test organisms was pipetted onto the surface and left there for the set contact time. After the contact time, the stainless steel plates where added to a neutralizer, in a tube with glass beads, and the mixture was vortexed to let the glass beads release the test organisms from the surface. After 5 mins of neutralization, samples were taken and diluted (to concentration of 10-3 and 10-4) and added to a petri dish (size 90-100mm) and incubated for 20-24 hours at 36-37 degrees Celsius. After incubation, the petri dish was counted for colony forming units. The plates are further incubated for another 20-24 hours, and the colony forming units are recounted. If the number of colonies has increased, the higher number is used.
The composition comprising a), b), c) and d) applied to a surface, showed efficacy even 14 days after application. The compound a) alone showed no long-term efficacy, as after 3 days, there was no detectable biocidal effect on a surface where a) was applied alone, at out test concentration.
In a third aspect of the invention, the use of the compositions according to the first aspect of invention for manufacturing of various products is claimed, such as, for the manufacture of industrial, hotel, sport, food, beverage, pool, transportation vehicle, educational area and home care formulation, such as a biocidal composition for cleaning industrial production facilities (cooling, refrigerating and freezing devices, equipment for food processing and beverage production, etc.), or as an antifouling composition and care formulations, such as a biocidal compositions, antifouling compositions, disinfectant, all-purpose cleaner, laundry detergent, dishwashing liquid, deodorant, fabric conditioner, product for disinfection and sanitization of hard surfaces, floor cleaner, glass cleaner, kitchen cleaner, bath cleaner, sanitary cleaner, hygiene rinse product for fabrics, carpet cleaner, furniture cleaner, or a product for conditioning, sealing, caring or treating hard and soft surfaces; or for the manufacture of a personal care formulation, especially a deodorant, skin care preparation, bath preparation, cosmetic care preparation, foot-care preparation, light-protective preparation, skin-tanning preparation, depigmenting preparation, insect-repellent, antiperspirant, preparation for cleansing and caring for blemished skin, hair-removal preparation, shaving preparation, fragrance preparation, cosmetic hair-treatment preparation, antidandruff preparation, oral care composition.
In a forth aspect of the invention, the use of the compositions according to the first aspect of invention as various products is claimed, such as industrial, hotel, sport, food, beverage, pool, transportation vehicle, educational area and home care formulation, such as a biocidal composition for cleaning industrial production facilities (cooling, refrigerating and freezing devices, equipment for food processing and beverage production, etc.), or as an antifouling composition, disinfectant, all-purpose cleaner, laundry detergent, dishwashing liquid, deodorant, fabric conditioner, product for disinfection and sanitization of hard surfaces, floor cleaner, glass cleaner, kitchen cleaner, bath cleaner, sanitary cleaner, hygiene rinse product for fabrics, carpet cleaner, furniture cleaner, or a product for conditioning, sealing, caring or treating hard and soft surfaces; or for the manufacture of a personal care formulation, especially a deodorant, skin care preparation, bath preparation, cosmetic care preparation, foot-care preparation, light-protective preparation, skin-tanning preparation, depigmenting preparation, insect-repellent, anti- perspirant, preparation for cleansing and caring for blemished skin, hair-removal preparation, shaving preparation, fragrance preparation, cosmetic hair-treatment preparation, antidandruff preparation, oral care composition.
Specific embodiments of the invention
The invention has been described with reference to a number of embodiments and aspects. However, the person skilled in the art may amend such embodiments and aspects while remaining within the scope of the appended patent claims. Our claimed biocide is Lactic Acid at concentrations of 0.1-1wt.%, in the form of the L-lactic acid isomer, for example from the product series Purac by Corbion, or 80wt.% L(+)-Lactic Acid by Merck or L(+)-Lactic Acid by Jungbunzlauer, or the racemic lactic acid, DL-Lactic acid, for example from the product series Purac by Corbion or 85wt.% DL-Lactic Acid by Merck or DL-Lactic Acid by Wilke International Inc.
The polyethyleneimine is from the group of polyethyleneimines of molecular weight higher than 400 g/mol, and preferably has a number-average molecular weight in the range from 500 to 2 000 000 g/mol, especially 750 g/mol to 100 000 g/mol, said polyethyleneimine is a homopolymer, or an oligomer or polymer grafted with 0.01 to 100 parts by weight of ethylene oxide on 1 part by weight of the polyethyleneimine, most preferably, the polyethyleneimine is a branched polyethyleneimine homopolymer, whose uncharged form conforms to the empirical formula -(CH2-CH2-NH)n- wherein n ranges from approximately 10 to 100000, or is a grafted variant thereof, for example, PEI from the Lupasol group of products by BASF, or from the polyethyleneimine group of products form Merck, or the modified PEI by Appeartex AB.
The tensid (compound c) is chosen from the group of non-ionic tensides, produced using an environment-friendly production, for example, Plantacare product line.
The primer is a Cocamidopropyl Betaine, chosen from the Dehyton group by BASF.
Some specific novel and inventive formulations in this scope that have proven efficacy are disclosed in the following embodiments:
EMBODIMENT 1
Compositions comprising 0.1-1 wt.% of a) L(+)-Lactic Acid; 0.0001-0.2wt.% of b) modified PEI (for example, A-200 by Appeartex AB); 0.1-5wt.% of c) D-Glucopyranose, oligomers, decyl octyl glycosides(for example, Plantacare 810UP by BASF) and 0.01-1wt.% of d) Cocamidopropyl Betaine (for example, Dehyton PK45 by BASF).
EMBODIMENT 2
Compositions comprising 0.1-1 wt.% of a) DL-Lactic Acid; 0.0001-0.2wt.% of b) modified PEI (for example, A-200 by Appeartex AB); 0.1-5wt.% of c) D-Glucopyranose, oligomers, decyl octyl glycosides (for example, Plantacare 810UP by BASF) and 0.01-1wt.% of d) Cocamidopropyl Betaine (for example, Dehyton PK45 by BASF).
EMBODIMENT 3
Compositions comprising 0.1-1 wt.% of a) L(+)-Lactic Acid; 0.0001-0.2wt.% of b) modified PEI (for example, A-200 by Appeartex AB); and 0.1-5wt.% of c) D-Glucopyranose, oligomers, decyl octyl glycosides (for example, Plantacare 810UP by BASF).
EMBODIMENT 4
Compositions comprising 0.1-1 wt.% of biocide a) DL-Lactic Acid (for example, Purac by Corbion); 0.0001-0.2wt.% of b) modified PEI (for example, A-200 by Appeartex AB) and 0.15wt.% of c) D-Glucopyranose, oligomers, decyl octyl glycosides (for example, Plantacare 810UP by BASF).
EMBODIMENT 5
Compositions comprising 0.1-1 wt.% of a) DL-Lactic Acid (for example, by Corbion); 0.00010.5wt.% of b) PEI (for example, Lupasol FG by BASF); and 0.1-5wt.% of c) D-Glucopyranose, oligomers, decyl octyl glycosides (for example, Plantacare 810UP by BASF).
EMBODIMENT 6
Compositions comprising 0.1-1 wt.% of a) L(+)-Lactic Acid; 0.0001-0.5wt.% of b) PEI (Lupasol FG by BASF); and 0.1-5wt.% of c) D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF).
EXAMPLE 1
A composition comprising 0.9wt.% L(+)-Lactic Acid (Purac from Corbion), 0.1wt.% modified PEI (A-200 by Appeartex AB), 0.9wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF) and 0.1wt.% Cocamidopropyl Betaine (Dehyton PK45 by BASF).
EXAMPLE 2
A composition comprising 0.9wt.% L(+)-Lactic Acid (by Merck), 0.1wt.% modified PEI (A-200 by Appeartex AB), 0.9wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF) and 0.1wt.% Cocamidopropyl Betaine (Dehyton PK45 by BASF).
EXAMPLE 3
A composition comprising 0.9wt.% DL-Lactic Acid (by Corbion), 0.1wt.% modified PEI (A-200 by Appeartex AB), 0.9wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF) and 0.1wt.% Cocamidopropyl Betaine (Dehyton PK45 by BASF).
EXAMPLE 4
A composition comprising 0.9wt.% DL-Lactic Acid (by Merck), 0,1wt.% modified PEI (A-200 by Appeartex AB), 0.9wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF) and 0.1wt.% Cocamidopropyl Betaine (Dehyton PK45 by BASF).
EXAMPLE 5
A composition comprising 0.9wt.% L(+)-Lactic Acid (Purac by Corbion), 0.1wt.% modified PEI (A-200 by Appeartex AB) and 1wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF).
EXAMPLE 6
A composition comprising 0.9wt.% L(+)-Lactic Acid (by Merck), 0.1wt.% modified PEI (A-200 by Appeartex AB) and 1wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF).
EXAMPLE 7
A composition comprising 0.9 wt.% DL-Lactic Acid (by Corbion), 0.1wt.% modified PEI (A200 by Appeartex AB) and 1wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF).
EXAMPLE 8
A composition comprising 0.9 wt.% DL-Lactic Acid (by Merck), 0.1wt.% modified PEI (A-200 by Appeartex AB) and 1wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF).
EXAMPLE 9
A composition comprising 0.9wt.% L(+)-Lactic Acid (Purac from Corbion), 0.25wt.% PEI (Lupasol FG by BASF), 0.9wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF) and 0.1wt.% Cocamidopropyl Betaine (Dehyton PK45 by BASF).
EXAMPLE 10
A composition comprising 0.9wt.% L(+)-Lactic Acid (by Merck), 0.25wt.% PEI (Lupasol FG by BASF), 0.9wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF) and 0.1wt.% Cocamidopropyl Betaine (Dehyton PK45 by BASF).
EXAMPLE 11
A composition comprising 0.9wt.% DL-Lactic Acid (by Corbion), 0.25wt.% PEI (Lupasol FG by BASF), 0.9wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF) and 0.1wt.% Cocamidopropyl Betaine (Dehyton PK45 by BASF).
EXAMPLE 12
A composition comprising 0.9wt.% DL-Lactic Acid (by Merck), 0.25wt.% PEI (Lupasol FG by BASF), 0.9wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF) and 0.1wt.% Cocamidopropyl Betaine (Dehyton PK45 by BASF).
EXAMPLE 13
A composition comprising 0.9wt.% L(+)-Lactic Acid (Purac by Corbion), 0.25wt.% PEI (Lupasol FG by BASF) and 1wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF).
EXAMPLE 14
A composition comprising 0.9wt.% L(+)-Lactic Acid (by Merck), 0.25wt.% PEI (Lupasol FG by BASF) and 1wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF).
EXAMPLE 15
A composition comprising 0.9 wt.% DL-Lactic Acid (by Corbion), 0.25wt.% PEI (Lupasol FG by BASF) and 1wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF).
EXAMPLE 16
A composition comprising 0.9 wt.% DL-Lactic Acid (by Merck), 0.25wt.% PEI (Lupasol FG by BASF) and 1wt.% D-Glucopyranose, oligomers, decyl octyl glycosides (Plantacare 810UP by BASF).

Claims (10)

1. Sammensætning, der omfatter kun et antimikrobielt middel (a), hvor dette ene antimikrobielle middel er valgt fra gruppen bestående af L - (+) - mælkesyre (denne isomer kaldes også (S) -mælkesyre) og racemisk mælkesyre ( også kaldet DL-mælkesyre, der omfatter en blanding af de to optiske isomerer i lige store mængder), og et polymerbindemiddel (b) valgt blandt polyethyleniminer.A composition comprising only one antimicrobial agent (a), wherein this one antimicrobial agent is selected from the group consisting of L - (+) - lactic acid (this isomer is also called (S) -lactic acid) and racemic lactic acid (also called DL -lactic acid comprising a mixture of the two optical isomers in equal amounts), and a polymeric binder (b) selected from polyethyleneimines. 2. Sammensætning ifølge krav 1, hvor udvalgte polyethyleniminer har molekylvægt højere end 400 g / mol og fortrinsvis har en antalsgennemsnitlig molekylvægt i området fra 500 til 2 000 000 g / mol, især 750 g / mol til 100 000 g / mol, hvor polyethylenimin er en homopolymer eller en oligomer eller polymer modificeret med 0,01 til 100 vægtdele ethylenoxid på 1 vægtdel polyethylenimin, mest foretrukket er en polyethylenimine i form af en forgrenet polyethylenimin-homopolymer, hvis uladede form er i overensstemmelse til den empiriske formel - (CH2-CH2-NH) n- hvor n varierer fra ca. 10 til 100000 eller er en modificeret variant deraf.A composition according to claim 1, wherein selected polyethyleneimines have molecular weights higher than 400 g / mol and preferably have a number average molecular weight in the range from 500 to 2,000,000 g / mol, especially 750 g / mol to 100,000 g / mol, wherein polyethyleneimine is a homopolymer or an oligomer or polymer modified with 0.01 to 100 parts by weight of ethylene oxide on 1 part by weight of polyethyleneimine, most preferably a polyethyleneimine in the form of a branched polyethyleneimine homopolymer whose uncharged form is in accordance with the empirical formula - (CH2- CH2-NH) n- where n varies from approx. 10 to 100000 or is a modified variant thereof. 3. Sammensætning ifølge et hvilket som helst af kravene 1 til 2, hvilken sammensætning indeholder 0,001 til 1 vægtprocent af det antimikrobielle middel (a) i forhold til den samlede vægt af sammensætningen.A composition according to any one of claims 1 to 2, which composition contains 0.001 to 1% by weight of the antimicrobial agent (a) relative to the total weight of the composition. 4. Sammensætning ifølge et hvilket som helst af kravene 1 til 3, hvilken sammensætning indeholder 0,001 til 1 vægtprocent af polyethylenimin (b), fortrinsvis 0,001 til 0,5 vægtprocent, mest fortrinsvis 0,1 vægtprocent af polyethylenimin (b) i forhold til den samlede vægt af sammensætningen.A composition according to any one of claims 1 to 3, which composition contains 0.001 to 1% by weight of polyethyleneimine (b), preferably 0.001 to 0.5% by weight, most preferably 0.1% by weight of polyethyleneimine (b) relative to the total weight of the composition. 5. Sammensætning ifølge et hvilket som helst af kravene 1 til 4, omfattende mindst en yderligere komponent (c) valgt fra gruppen bestående af tensider, overfladeaktive midler, hydrotropiske midler, yderligere additiver, der kan forbedre den antimikrobielle virkning, og stabilisere biocid (a) og / eller polyethylenimin, især valgt blandt overfladeaktive stoffer, såsom gruppen omfattende tensider, anioniske overfladeaktive stoffer, kationiske overfladeaktive stoffer, ikke-ioniske overfladeaktive midler, amfotere overfladeaktive midler; fortrinsvis omfatter komponent (c) Coco-glucosid.A composition according to any one of claims 1 to 4, comprising at least one further component (c) selected from the group consisting of surfactants, surfactants, hydrotropic agents, additional additives capable of enhancing the antimicrobial effect and stabilizing biocide (a). ) and / or polyethyleneimine, especially selected from surfactants, such as the group comprising surfactants, anionic surfactants, cationic surfactants, nonionic surfactants, amphoteric surfactants; preferably component (c) comprises Coco-glucoside. 6. Sammensætning ifølge krav 5, hvilken sammensætning indeholder 0,001 til 1 vægtprocent af et overfladeaktivt middel (c) i forhold til den samlede vægt af sammensætningen.A composition according to claim 5, which composition contains 0.001 to 1% by weight of a surfactant (c) relative to the total weight of the composition. 7. Sammensætning ifølge krav 5 eller 6, omfattende mindst en yderligere komponent (d) til stabilisering og mere jævnt fordeling af komponent (c), idet komponenten (d) er et fedtsyreamidderivat med Betain-struktur, fortrinsvis Cocamidopropyl Betaine.A composition according to claim 5 or 6, comprising at least one further component (d) for stabilizing and more evenly distributing component (c), component (d) being a fatty acid amide derivative with Betaine structure, preferably Cocamidopropyl Betaine. 8. Anvendelse af en hvilken som helst af komponenterne (b), (c) og (d) i kompositioner som beskrevet i krav 1-7 som en booster for det antimikrobielle middel (a) til at opnå en synergetisk effekt.Use of any of the components (b), (c) and (d) in compositions as described in claims 1-7 as a booster for the antimicrobial agent (a) to achieve a synergistic effect. 9. Anvendelse af en sammensætning ifølge et hvilket som helst af kravene 1 til 7 til fremstilling af en formulering til pleje af en steder som industri (herunder mad og drikkevarer), hoteller, sportsfaciliteter, pools, transportkøretøjer, uddannelsesområder og private hjem, for exempel, en antibakteriel sammensætning til rengøring af industrielle produktionsfaciliteter (køling , køle- og fryseanordninger, udstyr til fødevareforarbejdning og drikkeproduktion osv.), eller som en antifouling sammensætning, plejeformulering, såsom et biocid, desinfektionsmiddel, rengøringsmiddel til alle formål, vaskevaskemiddel, opvaskemiddel, deodorant, stofbalsam, produkt til desinfektion og desinficering af hårde overflader, gulvrens, glasrens, køkkenrens, badrens, hygiejnisk rengøringsprodukt til stof, tæpperensere, møblerens rengøringsmiddel eller et produkt til konditionering, forsegling, pleje eller behandling af hårdt og blødt overflader; eller til fremstilling af en personlig plejeformulering, især en deodorant, hudplejepræparat, badepræparat, kosmetisk plejepræparat, fodplejepræparat, let beskyttende præparat, hudbruner præparat, depigmenteringspræparat, insektafvisende, antiperspirant , forberedelse til rensning og pleje af beskadiget hud, hårfjerningsforberedelse, barberingsforberedelse, duftpræparat, kosmetisk hårbehandlingspræparat, antidandruff præparat eller en mund pleje sammensætning.Use of a composition according to any one of claims 1 to 7 in the manufacture of a formulation for the care of a place such as industry (including food and beverages), hotels, sports facilities, pools, transport vehicles, educational areas and private homes, for example , an antibacterial composition for cleaning industrial production facilities (refrigeration, refrigeration and freezing devices, food processing and beverage production equipment, etc.), or as an antifouling composition, care formulation such as a biocide, disinfectant, all-purpose cleaner, detergent, dishwashing detergent, deodorant , fabric conditioner, product for disinfection and disinfection of hard surfaces, floor cleaner, glass cleaner, kitchen cleaner, bath cleaner, hygienic cleaning product for fabric, carpet cleaners, furniture cleaner or a product for conditioning, sealing, care or treatment of hard and soft surfaces; or for the manufacture of a personal care formulation, in particular a deodorant, skin care preparation, bath preparation, cosmetic care preparation, foot care preparation, light protective preparation, skin tanning preparation, depigmentation preparation, insect repellent, antiperspirant, preparation for cleansing and skin preparation, hair treatment preparation, antidandruff preparation or a mouth care composition. 10. Anvendelse af en sammensætning i henhold til en af krav 1 til 7 som en formulering til pleje for industriel, Hotel, sport, mad, drikkevarer, pool, transport køretøj, uddannelsesområde og hjemme anvendelser, såsom en biocid sammensætning til rensning af industrielle produktionsfaciliteter (køling, køle-og fryse anordninger, udstyr til forarbejdning af fødevarer og drikkevareproduktion osv.) eller som en antifoulingsammensætning, pleje formulering, såsom et biocid, desinfektionsmiddel, rensemiddel, vaskemiddel, deodorant, Fabric conditioner, produkt til desinfektion og desinficering af hårde overflader, gulvrens, glasrens, køkkenrens, badrens, sanitær rens, hygiejniske skyllemidler til stof, tæpperens, møbelrens, eller et produkt til konditionering , forsegling, pleje eller behandling af hårde og bløde overflader; eller som en personlig pleje formulering, især en deodorant, hudpleje forberedelse, bad forberedelse, kosmetisk pleje forberedelse, mund-pleje forberedelse, lysbeskyttende forberedelse, hudbruner forberedelse, depigmentering forberedelse, insektfrastødende, antiperspirant, forberedelse til rensning og pleje af beskadiget hud, forberedelse af hårfjerning, barberings forberedelse, duft præparat, kosmetisk hårbehandlings forberedelse, skæl præparat eller en mund pleje sammensætning.Use of a composition according to any one of claims 1 to 7 as a formulation for the care of industrial, hotel, sports, food, beverage, pool, transport vehicle, education area and home applications, such as a biocidal composition for cleaning industrial production facilities (refrigeration, refrigeration and freezing devices, food processing and beverage processing equipment, etc.) or as an antifouling composition, care formulation, such as a biocide, disinfectant, detergent, detergent, deodorant, Fabric conditioner, product for disinfection and disinfection of hard surfaces , floor cleaner, glass cleaner, kitchen cleaner, bath cleaner, sanitary cleaner, hygienic fabric softener, carpet cleaner, furniture cleaner, or a product for conditioning, sealing, caring for or treating hard and soft surfaces; or as a personal care formulation, especially a deodorant, skin care preparation, bath preparation, cosmetic care preparation, mouth-care preparation, light-protective preparation, tanning preparation, depigmentation preparation, insect repellent, antiperspirant, preparation for cleansing and care of damaged skin, preparation of hair removal, shaving preparation, fragrance preparation, cosmetic hair treatment preparation, dandruff preparation or a mouth care composition.
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