DK1761650T3 - Humant autisme modtagelighedsgen, der koder for PRKCB1 og anvendelser deraf - Google Patents

Humant autisme modtagelighedsgen, der koder for PRKCB1 og anvendelser deraf

Info

Publication number
DK1761650T3
DK1761650T3 DK05766789T DK05766789T DK1761650T3 DK 1761650 T3 DK1761650 T3 DK 1761650T3 DK 05766789 T DK05766789 T DK 05766789T DK 05766789 T DK05766789 T DK 05766789T DK 1761650 T3 DK1761650 T3 DK 1761650T3
Authority
DK
Denmark
Prior art keywords
disorder
gene
autism
diagnosis
prevention
Prior art date
Application number
DK05766789T
Other languages
English (en)
Inventor
Anne Philippi
Francis Rousseau
Peter Brooks
Joerg Hager
Original Assignee
Integragen Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Integragen Sa filed Critical Integragen Sa
Application granted granted Critical
Publication of DK1761650T3 publication Critical patent/DK1761650T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
DK05766789T 2004-07-01 2005-06-30 Humant autisme modtagelighedsgen, der koder for PRKCB1 og anvendelser deraf DK1761650T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58413204P 2004-07-01 2004-07-01
PCT/IB2005/002381 WO2006003523A2 (en) 2004-07-01 2005-06-30 Human autism susceptibility gene encoding prkcb1 and uses thereof

Publications (1)

Publication Number Publication Date
DK1761650T3 true DK1761650T3 (da) 2009-06-29

Family

ID=34982198

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05766789T DK1761650T3 (da) 2004-07-01 2005-06-30 Humant autisme modtagelighedsgen, der koder for PRKCB1 og anvendelser deraf

Country Status (10)

Country Link
US (2) US20080193464A1 (da)
EP (1) EP1761650B1 (da)
JP (1) JP2008504838A (da)
AT (1) ATE424469T1 (da)
AU (1) AU2005258841B2 (da)
CA (1) CA2571370A1 (da)
DE (1) DE602005013080D1 (da)
DK (1) DK1761650T3 (da)
IL (1) IL179831A (da)
WO (1) WO2006003523A2 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE482290T1 (de) * 2005-03-24 2010-10-15 Integragen Sa Ein transmembranprotein kodierendes humanes autismus-suszeptibilitätsgen und dessen verwendung
US20070292962A1 (en) * 2006-04-10 2007-12-20 Duke University Methods and compositions for genetic markers for autism
WO2008126932A2 (en) * 2007-04-09 2008-10-23 Riken Epigenetical regulation of brain plasticity
US20100248235A1 (en) * 2007-10-04 2010-09-30 Scherer Stephen W Biomarkers for autism spectrum disorders
WO2011022292A2 (en) * 2009-08-19 2011-02-24 Lunera Research, Inc. Method of treating bipolar disorder or depression using an antiestrogen
CA2853945C (en) * 2011-10-31 2020-09-22 The Johns Hopkins University Methods and compositions for treatment of autism
EP2724721A1 (en) * 2012-10-26 2014-04-30 Matentzoglu, Konstantin Composition for use in the treatment of Angelman syndrome and/or autism spectrum disorder, the use of such composition and a method for manufacturing a medicament for the treatment of Angelman syndrome and/or autism spectrum disorder

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861719A (en) 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
US5278056A (en) 1988-02-05 1994-01-11 The Trustees Of Columbia University In The City Of New York Retroviral packaging cell lines and process of using same
US5670488A (en) 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
DE69434860T2 (de) 1993-02-22 2007-03-15 The Rockefeller University Herstellung von helfer-freien retroviren mit hohem titer mittels transienter transfektion
FR2712812B1 (fr) 1993-11-23 1996-02-09 Centre Nat Rech Scient Composition pour la production de produits thérapeutiques in vivo.
IL116816A (en) 1995-01-20 2003-05-29 Rhone Poulenc Rorer Sa Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
JP2006515745A (ja) * 2002-10-23 2006-06-08 エクセリクシス， インク． 分枝形態形成のモディファイヤーとしてのｍａｐ２ｋ６及び使用方法

Also Published As

Publication number Publication date
IL179831A0 (en) 2007-05-15
IL179831A (en) 2011-06-30
EP1761650B1 (en) 2009-03-04
WO2006003523A3 (en) 2006-05-18
ATE424469T1 (de) 2009-03-15
DE602005013080D1 (de) 2009-04-16
US20100240539A1 (en) 2010-09-23
WO2006003523A2 (en) 2006-01-12
EP1761650A2 (en) 2007-03-14
US20080193464A1 (en) 2008-08-14
WO2006003523A8 (en) 2006-03-02
JP2008504838A (ja) 2008-02-21
AU2005258841B2 (en) 2010-07-01
CA2571370A1 (en) 2006-01-12
AU2005258841A1 (en) 2006-01-12

Similar Documents

Publication Publication Date Title
DK1761650T3 (da) Humant autisme modtagelighedsgen, der koder for PRKCB1 og anvendelser deraf
IL179751A0 (en) Human autism predisposition gene encoding a transcription factor and uses thereof
MY164376A (en) Phosphospecific antibodies recognizing tau
WO2014009733A3 (en) Therapeutic targets for alzheimer's disease
MX2011006091A (es) Inhibidores de imidazopirazina syk.
WO2006087634A3 (en) Uses of human autism susceptibility gene encoding a kinase
WO2007132292A3 (en) Therapy for alzheimer's disease
DK1656458T3 (da) Human autisme-susceptibilitetsgen og anvendelser deraf
BRPI0509477A (pt) compostos de sulfonamida para o tratamento de distúrbios neurodegenerativos
Ben‐Reuven et al. Modeling the autistic cell: iPSCs recapitulate developmental principles of syndromic and nonsyndromic ASD
DK1863937T3 (da) Humant autisme-susceptibilitetsgen kodende for et transmembranprotein og anvendelser deraf
ATE457985T1 (de) Substituierte pyrazinonderivate zur verwendung als arzneimittel
WO2010000089A8 (en) Stat3 and tyk2 as drug targets for neurodegenerative diseases
Rikos et al. TREM2 R47H (rs75932628) variant is unlikely to contribute to Multiple Sclerosis susceptibility and severity in a large Greek MS cohort
WO2006090288A3 (en) Human autism susceptibility genes encoding a neurotransmitter transporter and uses thereof
Edgünlü et al. A study of the impact of death receptor 4 (DR4) gene polymorphisms in Alzheimer’s disease
JP2017500306A5 (da)
WO2006003526A3 (en) Human autism susceptibility gene encoding otoa and uses thereof
ATE471322T1 (de) Substituierte pyrazinonderivate zur verwendung als arzneimittel
FR2856595B1 (fr) Methodes et compositions pour le traitement de deficits cognitifs.
Schuch et al. The Genetic Basis of Autism Spectrum Disorder
WO2007044932A3 (en) Methods for indentification of inhibitors of enzyme activity
ATE443160T1 (de) Für einen spannungsgesteuerten kaliumkanal kodierendes humanes adipositas- suszeptibilitätssgen und dessen verwendung
Parshukova et al. PROTEOLYTIC ACTIVITY OF IMMUNOGLOBULINS G OF PATIENTS WITH SCHIZOPHRENIA
ATE487714T1 (de) Imino-oxazolidine und ihre verwendung als antikoagulantien