DK176085A - 4-(nitrophenyl)-tetrahydropyridiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler - Google Patents

4-(nitrophenyl)-tetrahydropyridiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler Download PDF

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Publication number
DK176085A
DK176085A DK176085A DK176085A DK176085A DK 176085 A DK176085 A DK 176085A DK 176085 A DK176085 A DK 176085A DK 176085 A DK176085 A DK 176085A DK 176085 A DK176085 A DK 176085A
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DK
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Prior art keywords
tetrahydropyridines
nitrophenyl
different
medicines
procedures
Prior art date
Application number
DK176085A
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English (en)
Other versions
DK176085D0 (da
Inventor
Ulrich Rosentreter
Guenter Thomas
Andreas Knorr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK176085D0 publication Critical patent/DK176085D0/da
Publication of DK176085A publication Critical patent/DK176085A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Description

Figure DK176085AD00021
idet X' i definitionen af X svarer til og kan være såvel identisk med som forskellig fra X, og i definitionen 3 af R svarer til og kan være såvel identisk med som for-skellig fra R , samt deres fysiologisk acceptable salte er anvendelige som lægemidler, især som kredsldbspåvir-kende midler.
DK176085A 1984-04-19 1985-04-18 4-(nitrophenyl)-tetrahydropyridiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler DK176085A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843414801 DE3414801A1 (de) 1984-04-19 1984-04-19 4-(nitrophenyl)-tetrahydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3414801 1984-04-19

Publications (2)

Publication Number Publication Date
DK176085D0 DK176085D0 (da) 1985-04-18
DK176085A true DK176085A (da) 1985-10-20

Family

ID=6233988

Family Applications (1)

Application Number Title Priority Date Filing Date
DK176085A DK176085A (da) 1984-04-19 1985-04-18 4-(nitrophenyl)-tetrahydropyridiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler

Country Status (10)

Country Link
US (1) US4621093A (da)
EP (1) EP0158956B1 (da)
JP (1) JPS60233057A (da)
KR (1) KR850007590A (da)
AT (1) ATE46147T1 (da)
CA (1) CA1241655A (da)
DE (2) DE3414801A1 (da)
DK (1) DK176085A (da)
ES (1) ES8607235A1 (da)
IL (1) IL74921A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3544692A1 (de) * 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
DE3700307A1 (de) * 1987-01-08 1988-07-21 Bayer Ag Tetrahydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5350771A (en) * 1989-03-22 1994-09-27 Peter K. T. Pang Method and treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers
US5886012A (en) * 1989-03-22 1999-03-23 Peter K. T. Pang Method of treatment for disease associated with excessive PHF using combination therapy involving exogenous calcium and calcium channel blockers
ATE144419T1 (de) * 1989-03-22 1996-11-15 Peter K T Pang Hypertensiver faktor des parathyroids
US5514678A (en) * 1992-03-26 1996-05-07 E. I. Du Pont De Nemours And Company Arthropodicidal 1,2,4-triazinyl amides
AU2002311623A1 (en) * 2002-05-29 2003-12-12 Council Of Scientific And Industrial Research Process for the preparation of 1,4-dihydropyridines and novel 1,4-dihydropyridines useful as therapeutic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
US4361572A (en) * 1981-12-21 1982-11-30 Chugai Seiyaku Kabushiki Kaisha Tetrahydronicotinamide derivative, pharmaceutical compositions and use
DE3239273A1 (de) * 1982-10-23 1984-04-26 Bayer Ag, 5090 Leverkusen Tetrahydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
EP0125803A3 (en) * 1983-04-27 1987-01-21 FISONS plc Pharmaceutically active dihydropyridines

Also Published As

Publication number Publication date
IL74921A0 (en) 1985-08-30
DK176085D0 (da) 1985-04-18
EP0158956B1 (de) 1989-09-06
IL74921A (en) 1988-03-31
DE3414801A1 (de) 1985-10-24
DE3572808D1 (en) 1989-10-12
EP0158956A2 (de) 1985-10-23
EP0158956A3 (en) 1987-07-22
KR850007590A (ko) 1985-12-07
ES8607235A1 (es) 1986-06-01
ATE46147T1 (de) 1989-09-15
JPS60233057A (ja) 1985-11-19
ES542393A0 (es) 1986-06-01
CA1241655A (en) 1988-09-06
US4621093A (en) 1986-11-04

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