DK175531B1 - Leveringsvehikel med amphiphil-associeret aktiv bestanddel - Google Patents

Leveringsvehikel med amphiphil-associeret aktiv bestanddel Download PDF

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Publication number
DK175531B1
DK175531B1 DK198706511A DK651187A DK175531B1 DK 175531 B1 DK175531 B1 DK 175531B1 DK 198706511 A DK198706511 A DK 198706511A DK 651187 A DK651187 A DK 651187A DK 175531 B1 DK175531 B1 DK 175531B1
Authority
DK
Denmark
Prior art keywords
delivery vehicle
active ingredient
acid
amphiphil
magnetite
Prior art date
Application number
DK198706511A
Other languages
Danish (da)
English (en)
Other versions
DK651187A (da
DK651187D0 (da
Inventor
Crispin George Stewart Eley
Paul Gardner Schmidt
Gary Fujii
Original Assignee
Nexstar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25477566&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK175531(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc
Publication of DK651187D0 publication Critical patent/DK651187D0/da
Publication of DK651187A publication Critical patent/DK651187A/da
Application granted granted Critical
Publication of DK175531B1 publication Critical patent/DK175531B1/da

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Classifications

    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
    • H02M1/00—Details of apparatus for conversion
    • H02M1/08—Circuits specially adapted for the generation of control voltages for semiconductor devices incorporated in static converters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
    • H02M1/00—Details of apparatus for conversion
    • H02M1/06—Circuits specially adapted for rendering non-conductive gas discharge tubes or equivalent semiconductor devices, e.g. thyratrons, thyristors
DK198706511A 1986-12-15 1987-12-11 Leveringsvehikel med amphiphil-associeret aktiv bestanddel DK175531B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94209386A 1986-12-15 1986-12-15
US94209386 1986-12-15

Publications (3)

Publication Number Publication Date
DK651187D0 DK651187D0 (da) 1987-12-11
DK651187A DK651187A (da) 1988-06-16
DK175531B1 true DK175531B1 (da) 2004-11-22

Family

ID=25477566

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198706511A DK175531B1 (da) 1986-12-15 1987-12-11 Leveringsvehikel med amphiphil-associeret aktiv bestanddel

Country Status (11)

Country Link
EP (1) EP0272091B2 (no)
JP (1) JP2677572B2 (no)
KR (2) KR950015052B1 (no)
AT (1) ATE89717T1 (no)
AU (1) AU608264B2 (no)
CA (1) CA1319614C (no)
DE (1) DE3786005T3 (no)
DK (1) DK175531B1 (no)
ES (1) ES2056832T5 (no)
IE (1) IE60562B1 (no)
NO (1) NO171583C (no)

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US6146657A (en) 1989-12-22 2000-11-14 Imarx Pharmaceutical Corp. Gas-filled lipid spheres for use in diagnostic and therapeutic applications
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US5733572A (en) 1989-12-22 1998-03-31 Imarx Pharmaceutical Corp. Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
US5305757A (en) 1989-12-22 1994-04-26 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5705187A (en) 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
US6001335A (en) 1989-12-22 1999-12-14 Imarx Pharmaceutical Corp. Contrasting agents for ultrasonic imaging and methods for preparing the same
US5773024A (en) 1989-12-22 1998-06-30 Imarx Pharmaceutical Corp. Container with multi-phase composition for use in diagnostic and therapeutic applications
US5776429A (en) 1989-12-22 1998-07-07 Imarx Pharmaceutical Corp. Method of preparing gas-filled microspheres using a lyophilized lipids
US5922304A (en) 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US5246707A (en) * 1990-04-26 1993-09-21 Haynes Duncan H Sustained release delivery of water-soluble bio-molecules and drugs using phospholipid-coated microcrystals, microdroplets and high-concentration liposomes
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
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DK0555317T3 (da) * 1990-10-09 1995-08-07 Nexstar Pharmaceuticals Inc Phospholipid-analog-vesikel med en succinimidylsubstituent
US5205290A (en) 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US5874062A (en) 1991-04-05 1999-02-23 Imarx Pharmaceutical Corp. Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
US5464696A (en) * 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
WO1994026253A1 (en) * 1993-05-19 1994-11-24 The Liposome Company, Inc. Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer
US5411730A (en) * 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
US5736121A (en) 1994-05-23 1998-04-07 Imarx Pharmaceutical Corp. Stabilized homogenous suspensions as computed tomography contrast agents
US5630786A (en) * 1994-06-27 1997-05-20 Ionix Corporation Boron neutron capture enhancement of fast neutron therapy
US6743779B1 (en) 1994-11-29 2004-06-01 Imarx Pharmaceutical Corp. Methods for delivering compounds into a cell
DE19500665A1 (de) * 1995-01-12 1996-07-18 Axel Prof Dr Haase Verfahren zur ortsauflösenden Abbildung eines Bereiches eines biologischen Objektes mit Hilfe elektromagnetischer Strahlen unter Applikation von Kontrastmittel
US5830430A (en) 1995-02-21 1998-11-03 Imarx Pharmaceutical Corp. Cationic lipids and the use thereof
US5997898A (en) 1995-06-06 1999-12-07 Imarx Pharmaceutical Corp. Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US6139819A (en) 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
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US6231834B1 (en) 1995-06-07 2001-05-15 Imarx Pharmaceutical Corp. Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
DE69637441T2 (de) 1995-10-17 2009-03-05 Jagotec Ag Verabreichung unlöslicher arzneistoffe
DE69736981D1 (de) 1996-05-01 2007-01-04 Imarx Pharmaceutical Corp In vitro verfahren zum einbringen von nukleinsäuren in eine zelle
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US6414139B1 (en) 1996-09-03 2002-07-02 Imarx Therapeutics, Inc. Silicon amphiphilic compounds and the use thereof
ATE231004T1 (de) 1996-09-11 2003-02-15 Imarx Pharmaceutical Corp Verbesserte verfahren zur diagnostischen bilderzeugung unter verwendung eines kontrastmittels und eines vasodilators
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
FR2754828B1 (fr) * 1996-10-23 1998-12-24 Univ Toulouse Structure membranaire artificielle, procede et polymere pour sa preparation, procede de preparation de ce polymere, particule et film comprenant cette structure
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6143276A (en) 1997-03-21 2000-11-07 Imarx Pharmaceutical Corp. Methods for delivering bioactive agents to regions of elevated temperatures
US6090800A (en) 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
US6537246B1 (en) 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US6416740B1 (en) 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
US6548047B1 (en) 1997-09-15 2003-04-15 Bristol-Myers Squibb Medical Imaging, Inc. Thermal preactivation of gaseous precursor filled compositions
US6123923A (en) 1997-12-18 2000-09-26 Imarx Pharmaceutical Corp. Optoacoustic contrast agents and methods for their use
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
ATE259220T1 (de) 1998-05-29 2004-02-15 Skyepharma Canada Inc Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben
SK288117B6 (sk) 1998-11-20 2013-09-03 Skyepharma Canada Inc. Rapidly dispersing solid dry therapeutic dosage form
JP5102423B2 (ja) 2000-04-20 2012-12-19 オバン・エナジー・リミテッド 改善された水不溶性薬剤粒子の処理
ATE424811T1 (de) 2000-08-31 2009-03-15 Jagotec Ag Gemahlene partikel
DE10331439B3 (de) 2003-07-10 2005-02-03 Micromod Partikeltechnologie Gmbh Magnetische Nanopartikel mit verbesserten Magneteigenschaften
JPWO2006028129A1 (ja) * 2004-09-10 2008-05-08 東レ株式会社 医薬品製剤
RU2481125C2 (ru) 2006-12-18 2013-05-10 Колороббия Италия С.П.А. Магнитные наночастицы для применения при гипертермии, их приготовление и применение в магнитных системах для фармакологического использования
EP2719398B1 (en) * 2011-06-13 2016-01-20 National University Corporation Chiba University Medical tissue-marker and manufacturing method for same
JP6482604B2 (ja) * 2017-06-22 2019-03-13 教裕 南郷 外皮内溶解型ニードル及びニードル装置
CN110455848B (zh) * 2018-05-08 2024-02-23 国家纳米科学中心 基于络合反应放大信号的铁离子纵向弛豫时间传感器及其构建方法、用途
EP3714879A1 (en) * 2019-03-28 2020-09-30 Sisaf Ltd Structured encapsulated silicon-containing particles

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US4208294A (en) * 1979-02-12 1980-06-17 The United States Of America, As Represented By The Secretary Of The Interior Dilution stable water based magnetic fluids
PT81498B (pt) * 1984-11-23 1987-12-30 Schering Ag Processo para a preparacao de composicoes para diagnostico contendo particulas magneticas
EP0198765A3 (en) * 1985-04-09 1987-10-21 Georgetown University Preparation of liposomes
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes

Also Published As

Publication number Publication date
ATE89717T1 (de) 1993-06-15
CA1319614C (en) 1993-06-29
KR880007065A (ko) 1988-08-26
DE3786005T3 (de) 1999-04-01
EP0272091B2 (en) 1998-10-28
IE873387L (en) 1988-06-15
DE3786005T2 (de) 1993-09-02
AU8249487A (en) 1988-06-16
NO171583B (no) 1992-12-28
EP0272091A3 (en) 1988-10-12
IE60562B1 (en) 1994-07-27
KR950015052B1 (ko) 1995-12-21
DK651187A (da) 1988-06-16
JPS63233915A (ja) 1988-09-29
KR880008502A (ko) 1988-08-31
DE3786005D1 (de) 1993-07-01
NO171583C (no) 1993-04-07
DK651187D0 (da) 1987-12-11
NO875194L (no) 1988-06-16
AU608264B2 (en) 1991-03-28
ES2056832T3 (es) 1994-10-16
EP0272091B1 (en) 1993-05-26
NO875194D0 (no) 1987-12-14
JP2677572B2 (ja) 1997-11-17
EP0272091A2 (en) 1988-06-22
ES2056832T5 (es) 1999-04-16

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