DK174885A - Derivater af n-(3-phenylmethylthio-1-oxopropyl)-aminoeddikesyre i form af enantiomere eller blandinger, fremgangsmaade til fremstilling af forbindelserne og laegemiddel indeholdende disse - Google Patents

Derivater af n-(3-phenylmethylthio-1-oxopropyl)-aminoeddikesyre i form af enantiomere eller blandinger, fremgangsmaade til fremstilling af forbindelserne og laegemiddel indeholdende disse Download PDF

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Publication number
DK174885A
DK174885A DK174885A DK174885A DK174885A DK 174885 A DK174885 A DK 174885A DK 174885 A DK174885 A DK 174885A DK 174885 A DK174885 A DK 174885A DK 174885 A DK174885 A DK 174885A
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DK
Denmark
Prior art keywords
compounds
phenylmethylthio
oxopropyl
enantiomers
procedures
Prior art date
Application number
DK174885A
Other languages
English (en)
Other versions
DK174885D0 (da
Inventor
Jacques Comarmond
Luc Rivron
Thomas Purcell
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8406201A external-priority patent/FR2563219B1/fr
Priority claimed from FR8406200A external-priority patent/FR2563218B1/fr
Application filed by Synthelabo filed Critical Synthelabo
Publication of DK174885D0 publication Critical patent/DK174885D0/da
Publication of DK174885A publication Critical patent/DK174885A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

Figure DK174885AD00021
der omsættes med mercaptopropionsyre og videre med thionyl-chlorid og tilsidst med en aminosyre HoNCHCOOH og eventuel
^ I
«2 udskiftning af og/eller saltdannelse.
Forbindelserne anvendes som mucolytiske midler, ligesom de udviser andre fysiologiske herunder analgetiske aktiviteter.
DK174885A 1984-04-19 1985-04-18 Derivater af n-(3-phenylmethylthio-1-oxopropyl)-aminoeddikesyre i form af enantiomere eller blandinger, fremgangsmaade til fremstilling af forbindelserne og laegemiddel indeholdende disse DK174885A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8406201A FR2563219B1 (fr) 1984-04-19 1984-04-19 Derives d'acide n-(phenylmethylthio-3 oxo-1 propyl)- aminoacetique, leur preparation et leur application en therapeutique
FR8406200A FR2563218B1 (fr) 1984-04-19 1984-04-19 Derives d'acide n-((chloro-2 phenyl)methylthio-3 oxo-1 propyl)-aminoacetique substitue en a, leur preparation et leur application en therapeutique
FR8406200 1984-04-19
FR8406201 1984-04-19

Publications (2)

Publication Number Publication Date
DK174885D0 DK174885D0 (da) 1985-04-18
DK174885A true DK174885A (da) 1985-10-20

Family

ID=26223924

Family Applications (1)

Application Number Title Priority Date Filing Date
DK174885A DK174885A (da) 1984-04-19 1985-04-18 Derivater af n-(3-phenylmethylthio-1-oxopropyl)-aminoeddikesyre i form af enantiomere eller blandinger, fremgangsmaade til fremstilling af forbindelserne og laegemiddel indeholdende disse

Country Status (10)

Country Link
EP (1) EP0161172A1 (da)
AU (1) AU4138685A (da)
DK (1) DK174885A (da)
ES (1) ES8603395A1 (da)
FI (1) FI851550L (da)
GR (1) GR850951B (da)
HU (1) HUT38094A (da)
IL (1) IL74956A0 (da)
NO (1) NO851546L (da)
PT (1) PT80316B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0202759B1 (en) * 1985-04-19 1990-06-20 Smithkline Beecham Corporation Leukotriene antagonists
US5196563A (en) * 1986-12-17 1993-03-23 Ciba-Geigy Corporation N-phenyl-N-carboxythioureas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451186A (de) * 1961-11-02 1968-05-15 Santen Phamarceutical Co Ltd Verfahren zur Herstellung von N-Mercaptopropionylglycin und dessen Derivaten
JPS535112A (en) * 1976-03-08 1978-01-18 Santen Pharmaceutical Co Ltd New cysteine derivatives
IT1111384B (it) * 1978-12-21 1986-01-13 Sigma Tau Ind Farmaceuti Guaiacil esteri di derivati dello acido mercaptopropionico procedimento per la loro preparazione e loro uso terapeutico

Also Published As

Publication number Publication date
PT80316B (fr) 1987-02-16
EP0161172A1 (fr) 1985-11-13
AU4138685A (en) 1985-10-24
FI851550A0 (fi) 1985-04-18
GR850951B (da) 1985-11-25
ES542379A0 (es) 1985-12-16
FI851550L (fi) 1985-10-20
PT80316A (fr) 1985-05-01
ES8603395A1 (es) 1985-12-16
DK174885D0 (da) 1985-04-18
IL74956A0 (en) 1985-08-30
NO851546L (no) 1985-10-21
HUT38094A (en) 1986-04-28

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