DK1696935T3 - Hidtil ukendte derivater af morfin-6-glucuronid, farmaceutiske præparater indeholdende derivaterne, fremgangsmåde til fremstilling deraf og anvendelser deraf - Google Patents

Hidtil ukendte derivater af morfin-6-glucuronid, farmaceutiske præparater indeholdende derivaterne, fremgangsmåde til fremstilling deraf og anvendelser deraf

Info

Publication number
DK1696935T3
DK1696935T3 DK04816470T DK04816470T DK1696935T3 DK 1696935 T3 DK1696935 T3 DK 1696935T3 DK 04816470 T DK04816470 T DK 04816470T DK 04816470 T DK04816470 T DK 04816470T DK 1696935 T3 DK1696935 T3 DK 1696935T3
Authority
DK
Denmark
Prior art keywords
derivatives
morphine
glucuronide
preparation
processes
Prior art date
Application number
DK04816470T
Other languages
English (en)
Inventor
Jamal Temsamani
Roger Lahana
Patrick Mouchet
Original Assignee
Btg Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Btg Int Ltd filed Critical Btg Int Ltd
Application granted granted Critical
Publication of DK1696935T3 publication Critical patent/DK1696935T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK04816470T 2003-12-22 2004-12-22 Hidtil ukendte derivater af morfin-6-glucuronid, farmaceutiske præparater indeholdende derivaterne, fremgangsmåde til fremstilling deraf og anvendelser deraf DK1696935T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0315160A FR2864082B1 (fr) 2003-12-22 2003-12-22 Nouveau derive de la morphine-6-glucuronide, composition pharmaceutique le contenant et son utilisation pour le traitement de la douleur
PCT/FR2004/003342 WO2005063263A1 (fr) 2003-12-22 2004-12-22 Nouveaux derives de la morphine-6-glucuronide, compositions pharmaceutiques les contenant, leur procede de preparation et leurs utilisations

Publications (1)

Publication Number Publication Date
DK1696935T3 true DK1696935T3 (da) 2007-08-06

Family

ID=34630441

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04816470T DK1696935T3 (da) 2003-12-22 2004-12-22 Hidtil ukendte derivater af morfin-6-glucuronid, farmaceutiske præparater indeholdende derivaterne, fremgangsmåde til fremstilling deraf og anvendelser deraf

Country Status (12)

Country Link
US (1) US7365055B2 (da)
EP (1) EP1696935B8 (da)
AT (1) ATE358491T1 (da)
AU (1) AU2004308720A1 (da)
CA (1) CA2548921A1 (da)
DE (1) DE602004005752T2 (da)
DK (1) DK1696935T3 (da)
ES (1) ES2285568T3 (da)
FR (1) FR2864082B1 (da)
PL (1) PL1696935T3 (da)
PT (1) PT1696935E (da)
WO (1) WO2005063263A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2907121B1 (fr) 2006-10-12 2012-05-04 Neorphys Nouveaux derives morphiniques
FR2939436B1 (fr) * 2008-12-10 2010-12-17 Sanofi Aventis Synthese de morphine-6-glucuronide ou de l'un de ses derives
FR2939437B1 (fr) 2008-12-10 2010-12-17 Sanofi Aventis Derives de morphine-6-glucuronide, leur preparation et leur application en therapeutique
FR2939796B1 (fr) * 2008-12-11 2010-12-17 Sanofi Aventis Derives bicycliques de morphine-6-glucuronide, leur preparation et leur application en therapeutique
US8450089B2 (en) * 2009-11-23 2013-05-28 New York University Compounds as L-cystine crystallization inhibitors and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10513485A (ja) * 1995-11-29 1998-12-22 ロラボ エセ エレ オピエート性物質の糖結合体
FR2821272B1 (fr) * 2001-02-23 2004-12-17 Synt Em Composes constitues d'une molecule analgesique liee a un vecteur capable de vectoriser ladite molecule a travers la barriere hematoencephalique et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
FR2864082A1 (fr) 2005-06-24
WO2005063263A1 (fr) 2005-07-14
US20070116665A1 (en) 2007-05-24
EP1696935B1 (fr) 2007-04-04
PL1696935T3 (pl) 2007-10-31
CA2548921A1 (fr) 2005-07-14
ES2285568T3 (es) 2007-11-16
PT1696935E (pt) 2007-06-28
DE602004005752T2 (de) 2008-01-10
DE602004005752D1 (de) 2007-05-16
US7365055B2 (en) 2008-04-29
FR2864082B1 (fr) 2006-03-10
ATE358491T1 (de) 2007-04-15
EP1696935A1 (fr) 2006-09-06
AU2004308720A1 (en) 2005-07-14
EP1696935B8 (fr) 2007-06-20

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