DK1670769T3 - Benzimidazole derivatives, compositions containing them, their preparation and uses thereof - Google Patents

Benzimidazole derivatives, compositions containing them, their preparation and uses thereof

Info

Publication number
DK1670769T3
DK1670769T3 DK04768667T DK04768667T DK1670769T3 DK 1670769 T3 DK1670769 T3 DK 1670769T3 DK 04768667 T DK04768667 T DK 04768667T DK 04768667 T DK04768667 T DK 04768667T DK 1670769 T3 DK1670769 T3 DK 1670769T3
Authority
DK
Denmark
Prior art keywords
preparation
compositions containing
benzimidazole derivatives
benzimidazole
derivatives
Prior art date
Application number
DK04768667T
Other languages
Danish (da)
Inventor
Ziping Liu
Christopher Walpole
Hua Yang
Daniel Page
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1670769T3 publication Critical patent/DK1670769T3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14Radicals substituted by nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK04768667T 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, their preparation and uses thereof DK1670769T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0302573A SE0302573D0 (en) 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
PCT/GB2004/004124 WO2005030732A1 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Publications (1)

Publication Number Publication Date
DK1670769T3 true DK1670769T3 (en) 2009-08-10

Family

ID=29246982

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04768667T DK1670769T3 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, their preparation and uses thereof

Country Status (34)

Country Link
US (1) US8633235B2 (en)
EP (1) EP1670769B1 (en)
JP (1) JP4896721B2 (en)
KR (1) KR101170184B1 (en)
CN (2) CN1886379A (en)
AR (1) AR045819A1 (en)
AT (1) ATE430135T1 (en)
AU (1) AU2004276062B2 (en)
BR (1) BRPI0414780B8 (en)
CA (1) CA2539738C (en)
CO (1) CO5680443A2 (en)
CY (1) CY1110332T1 (en)
DE (1) DE602004020907D1 (en)
DK (1) DK1670769T3 (en)
ES (1) ES2324669T3 (en)
HK (1) HK1089436A1 (en)
HR (1) HRP20090388T1 (en)
IL (1) IL174215A0 (en)
IS (1) IS8422A (en)
MX (1) MXPA06003197A (en)
MY (1) MY140630A (en)
NO (1) NO20061839L (en)
NZ (1) NZ545736A (en)
PL (1) PL1670769T3 (en)
PT (1) PT1670769E (en)
RU (1) RU2346938C2 (en)
SA (1) SA04250310B1 (en)
SE (1) SE0302573D0 (en)
SI (1) SI1670769T1 (en)
TW (1) TW200521117A (en)
UA (1) UA86776C2 (en)
UY (1) UY28536A1 (en)
WO (1) WO2005030732A1 (en)
ZA (3) ZA200602446B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4667867B2 (en) 2002-08-02 2011-04-13 メルク・シャープ・エンド・ドーム・コーポレイション Substituted furo [2,3-b] pyridine derivatives
SE0302573D0 (en) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
JP2008514592A (en) * 2004-09-24 2008-05-08 アストラゼネカ・アクチエボラーグ Benzimidazole derivatives, compositions containing them, their preparation and their use III
EP1797077B1 (en) * 2004-09-24 2012-02-15 AstraZeneca AB Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof i
ATE545644T1 (en) 2004-09-24 2012-03-15 Astrazeneca Ab BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME, PRODUCTION THEREOF AND USES THEREOF I
CN101052639B (en) * 2004-09-24 2010-10-27 阿斯利康(瑞典)有限公司 Benzimidazole derivatives, composition containing thereof, its preparation method and application
JP2008518905A (en) 2004-11-02 2008-06-05 ファイザー株式会社 Sulfonylbenzimidazole derivatives
CN101233098A (en) * 2005-07-29 2008-07-30 阿斯利康(瑞典)有限公司 Process for the preparation of geminal ((difluorocycloalkyl)methyl) amines
TW200745049A (en) 2006-03-23 2007-12-16 Astrazeneca Ab New crystalline forms
TW200808769A (en) * 2006-04-18 2008-02-16 Astrazeneca Ab Therapeutic compounds
US20080139846A1 (en) * 2006-09-01 2008-06-12 Astrazeneca Ab New Process 298
US8236841B2 (en) * 2006-09-13 2012-08-07 Kyowa Hakko Kirin Co., Ltd. Fused heterocycle derivative
US20110086853A1 (en) * 2009-10-08 2011-04-14 William Brown Therapeutic Compounds
RU2454234C1 (en) * 2011-03-16 2012-06-27 Константин Михайлович Аверин 1,3-diethylbenzimidazolium salts as immunostimulating drugs and based pharmaceutical compositions
NZ702969A (en) * 2012-06-13 2016-12-23 Cytec Tech Corp Stabilizer compositions containing substituted chroman compounds and methods of use
CA2877786C (en) 2012-06-26 2020-08-25 Bayer Pharma Aktiengesellschaft N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products
CA3093189A1 (en) 2018-03-07 2019-09-12 Bayer Aktiengesellschaft Identification and use of erk5 inhibitors
US20220227729A1 (en) 2019-05-21 2022-07-21 Bayer Aktiengesellschaft Identification and use of kras inhibitors
CN112010789A (en) * 2019-05-31 2020-12-01 中国科学院上海药物研究所 Vinyl sulfonamide or vinyl amide compounds, and preparation method and application thereof
WO2023166450A1 (en) * 2022-03-04 2023-09-07 삼진제약주식회사 Novel heterocyclic compound and pharmaceutical composition comprising same

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1604908A (en) 1965-06-24 1971-05-15 Substd benzimidazoles - with anthelmintic,fungicidal activity and some with antiviral and antibacterial activity
FR5354M (en) 1965-09-10 1967-09-11
US5387600A (en) 1992-07-30 1995-02-07 Fuji Photo Film Co., Ltd. Treating arteriosclerosis using benzimidazole compositions
DE4237597A1 (en) 1992-11-06 1994-05-11 Bayer Ag Substituted benzimidazoles
DE4237617A1 (en) 1992-11-06 1994-05-11 Bayer Ag Use of substituted benzimidazoles
DE4237557A1 (en) 1992-11-06 1994-05-11 Bayer Ag Substituted benzimidazoles
IL124969A (en) 1995-12-28 2002-09-12 Fujisawa Pharmaceutical Co Benzimidazole derivatives, processes for their preparation and pharmaceutical compositions containing them
US6348032B1 (en) 1998-11-23 2002-02-19 Cell Pathways, Inc. Method of inhibiting neoplastic cells with benzimidazole derivatives
WO2001012600A1 (en) 1999-08-12 2001-02-22 Cor Therapeutics, Inc. INHIBITORS OF FACTOR Xa
US6720317B1 (en) 1999-09-17 2004-04-13 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
BR0014078A (en) 1999-09-17 2002-12-31 Millennium Pharm Inc Xa factor inhibitors
US6632815B2 (en) 1999-09-17 2003-10-14 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
US6844367B1 (en) 1999-09-17 2005-01-18 Millennium Pharmaceuticals, Inc. Benzamides and related inhibitors of factor Xa
US7115645B2 (en) 2000-01-14 2006-10-03 Schering Aktiengesellschaft 1,2 diarylbenzimidazoles and their pharmaceutical use
CN1301975C (en) * 2000-01-14 2007-02-28 舍林股份公司 1,2-diaryl benzimidazole derivative for treating illnesses associated with microglia activation
US7329679B2 (en) * 2000-01-27 2008-02-12 Schering Aktiengesellschaft 1,2 Diarylbenzimidazoles and their pharmaceutical use
WO2001064642A2 (en) 2000-02-29 2001-09-07 Cor Therapeutics, Inc. Benzamides and related inhibitors of factor xa
WO2002000651A2 (en) 2000-06-27 2002-01-03 Bristol-Myers Squibb Pharma Company Factor xa inhibitors
JP2004515496A (en) 2000-12-07 2004-05-27 アストラゼネカ・アクチエボラーグ Benzimidazole therapeutic agent
SE0101387D0 (en) 2001-04-20 2001-04-20 Astrazeneca Ab Novel compounds
EP1403255A4 (en) 2001-06-12 2005-04-06 Sumitomo Pharma Rho KINASE INHIBITORS
AR043633A1 (en) 2003-03-20 2005-08-03 Schering Corp CANABINOID RECEIVERS LINKS
SE0301701D0 (en) 2003-06-10 2003-06-10 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0301699D0 (en) 2003-06-10 2003-06-10 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
WO2005007625A2 (en) 2003-07-14 2005-01-27 The University Of Tennessee Research Foundation Heterocyclic amides with anti-tuberculosis activity
WO2005021547A2 (en) 2003-08-28 2005-03-10 Pharmaxis Pty Ltd. Heterocyclic cannabinoid cb2 receptor antagonists
SE0302572D0 (en) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302573D0 (en) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302570D0 (en) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302571D0 (en) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
WO2005113542A2 (en) 2004-05-20 2005-12-01 Elan Pharmaceuticals, Inc. N-cyclic sulfonamido inhibitors of gamma secretase
WO2006009876A2 (en) 2004-06-17 2006-01-26 Cengent Therapeutics, Inc. Trisubstituted nitrogen modulators of tyrosine phosphatases
KR101155288B1 (en) 2004-07-30 2012-07-02 엑셀리시스, 인코포레이티드 Pyrrole Derivatives as Pharmaceutical Agents
US20060052421A1 (en) 2004-09-09 2006-03-09 Eastman Kodak Company Conjugation agent
JP2008514592A (en) 2004-09-24 2008-05-08 アストラゼネカ・アクチエボラーグ Benzimidazole derivatives, compositions containing them, their preparation and their use III
WO2006033628A1 (en) 2004-09-24 2006-03-30 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
ATE545644T1 (en) * 2004-09-24 2012-03-15 Astrazeneca Ab BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME, PRODUCTION THEREOF AND USES THEREOF I
EP1797077B1 (en) 2004-09-24 2012-02-15 AstraZeneca AB Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof i
WO2006033633A1 (en) 2004-09-24 2006-03-30 Astrazeneca Ab Compounds, compositions containing them, preparations thereof and uses thereof ii
JP2008514591A (en) 2004-09-24 2008-05-08 アストラゼネカ・アクチエボラーグ Benzimidazole derivatives and their use as cannabinoid receptor ligands
JP2008514589A (en) 2004-09-24 2008-05-08 アストラゼネカ・アクチエボラーグ Compounds, compositions containing them, their preparation and their use IIII
EP1794150A1 (en) 2004-09-24 2007-06-13 AstraZeneca AB Benzimidazole derivatives and their use as cannabinoid receptor ligands I
JP2008518905A (en) 2004-11-02 2008-06-05 ファイザー株式会社 Sulfonylbenzimidazole derivatives
WO2006078941A2 (en) 2005-01-20 2006-07-27 Sirtris Pharmaceuticals, Inc. Novel sirtuin activating compounds and methods of use thereof
TW200745049A (en) 2006-03-23 2007-12-16 Astrazeneca Ab New crystalline forms
TW200808769A (en) 2006-04-18 2008-02-16 Astrazeneca Ab Therapeutic compounds
TW200808772A (en) 2006-06-13 2008-02-16 Astrazeneca Ab Therapeutic compounds

Also Published As

Publication number Publication date
JP4896721B2 (en) 2012-03-14
ES2324669T3 (en) 2009-08-12
CO5680443A2 (en) 2006-09-29
EP1670769B1 (en) 2009-04-29
BRPI0414780A (en) 2006-11-21
KR101170184B1 (en) 2012-07-31
SA04250310B1 (en) 2009-01-19
IL174215A0 (en) 2006-08-01
WO2005030732A1 (en) 2005-04-07
EP1670769A1 (en) 2006-06-21
CN102010373A (en) 2011-04-13
HRP20090388T1 (en) 2009-08-31
SI1670769T1 (en) 2009-10-31
CA2539738A1 (en) 2005-04-07
US8633235B2 (en) 2014-01-21
CN1886379A (en) 2006-12-27
CA2539738C (en) 2011-11-22
UY28536A1 (en) 2005-04-29
ZA200702226B (en) 2009-01-28
DE602004020907D1 (en) 2009-06-10
BRPI0414780B8 (en) 2021-05-25
NZ545736A (en) 2009-11-27
ZA200702131B (en) 2008-08-27
IS8422A (en) 2006-04-21
ZA200602446B (en) 2007-09-26
MXPA06003197A (en) 2006-06-23
US20080207612A1 (en) 2008-08-28
CY1110332T1 (en) 2015-01-14
NO20061839L (en) 2006-06-26
AU2004276062B2 (en) 2008-05-22
KR20070001052A (en) 2007-01-03
JP2007506721A (en) 2007-03-22
AU2004276062A1 (en) 2005-04-07
UA86776C2 (en) 2009-05-25
HK1089436A1 (en) 2006-12-01
SE0302573D0 (en) 2003-09-26
PL1670769T3 (en) 2009-09-30
PT1670769E (en) 2009-07-09
RU2006113371A (en) 2007-11-10
TW200521117A (en) 2005-07-01
ATE430135T1 (en) 2009-05-15
AR045819A1 (en) 2005-11-16
RU2346938C2 (en) 2009-02-20
BRPI0414780B1 (en) 2018-10-23
MY140630A (en) 2010-01-15

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