DK166430B1 - Fremgangsmaade til fremstilling af et monosaccharidholdigt praeparat - Google Patents
Fremgangsmaade til fremstilling af et monosaccharidholdigt praeparat Download PDFInfo
- Publication number
- DK166430B1 DK166430B1 DK134377A DK134377A DK166430B1 DK 166430 B1 DK166430 B1 DK 166430B1 DK 134377 A DK134377 A DK 134377A DK 134377 A DK134377 A DK 134377A DK 166430 B1 DK166430 B1 DK 166430B1
- Authority
- DK
- Denmark
- Prior art keywords
- composition
- process according
- citric acid
- monosaccharide
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 22
- 238000002360 preparation method Methods 0.000 title description 39
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 60
- 239000000203 mixture Substances 0.000 claims description 55
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 38
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 35
- 150000002772 monosaccharides Chemical class 0.000 claims description 24
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 23
- 150000001413 amino acids Chemical class 0.000 claims description 21
- 239000004471 Glycine Substances 0.000 claims description 19
- 239000011780 sodium chloride Substances 0.000 claims description 18
- 239000008103 glucose Substances 0.000 claims description 15
- 150000003839 salts Chemical class 0.000 claims description 9
- 239000003242 anti bacterial agent Substances 0.000 claims description 5
- 239000007864 aqueous solution Substances 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 150000001860 citric acid derivatives Chemical class 0.000 claims description 3
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 21
- 229960001031 glucose Drugs 0.000 description 21
- 235000001014 amino acid Nutrition 0.000 description 15
- 206010012735 Diarrhoea Diseases 0.000 description 11
- 241001465754 Metazoa Species 0.000 description 11
- 239000008121 dextrose Substances 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 244000309466 calf Species 0.000 description 7
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 7
- 235000019796 monopotassium phosphate Nutrition 0.000 description 7
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 7
- 238000010521 absorption reaction Methods 0.000 description 5
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 description 5
- 239000001354 calcium citrate Substances 0.000 description 5
- 239000003792 electrolyte Substances 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 235000013337 tricalcium citrate Nutrition 0.000 description 5
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 4
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 3
- 229960003022 amoxicillin Drugs 0.000 description 3
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 description 3
- 229930182830 galactose Natural products 0.000 description 3
- 235000013336 milk Nutrition 0.000 description 3
- 239000008267 milk Substances 0.000 description 3
- 210000004080 milk Anatomy 0.000 description 3
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 description 3
- 239000011734 sodium Substances 0.000 description 3
- 229910052708 sodium Inorganic materials 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- PNNNRSAQSRJVSB-UHFFFAOYSA-N 2,3,4,5-tetrahydroxyhexanal Chemical compound CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 description 2
- 239000004475 Arginine Substances 0.000 description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 description 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 235000004279 alanine Nutrition 0.000 description 2
- 229960000723 ampicillin Drugs 0.000 description 2
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 239000004227 calcium gluconate Substances 0.000 description 2
- 235000013927 calcium gluconate Nutrition 0.000 description 2
- 229960004494 calcium gluconate Drugs 0.000 description 2
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 229940050410 gluconate Drugs 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 2
- 235000019341 magnesium sulphate Nutrition 0.000 description 2
- -1 mono- Chemical class 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 159000000001 potassium salts Chemical class 0.000 description 2
- 210000001187 pylorus Anatomy 0.000 description 2
- 210000000813 small intestine Anatomy 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- SOBHUZYZLFQYFK-UHFFFAOYSA-K trisodium;hydroxy-[[phosphonatomethyl(phosphonomethyl)amino]methyl]phosphinate Chemical compound [Na+].[Na+].[Na+].OP(O)(=O)CN(CP(O)([O-])=O)CP([O-])([O-])=O SOBHUZYZLFQYFK-UHFFFAOYSA-K 0.000 description 2
- VZSRBBMJRBPUNF-UHFFFAOYSA-N 2-(2,3-dihydro-1H-inden-2-ylamino)-N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]pyrimidine-5-carboxamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C(=O)NCCC(N1CC2=C(CC1)NN=N2)=O VZSRBBMJRBPUNF-UHFFFAOYSA-N 0.000 description 1
- RMTFNDVZYPHUEF-XZBKPIIZSA-N 3-O-methyl-D-glucose Chemical compound O=C[C@H](O)[C@@H](OC)[C@H](O)[C@H](O)CO RMTFNDVZYPHUEF-XZBKPIIZSA-N 0.000 description 1
- CONKBQPVFMXDOV-QHCPKHFHSA-N 6-[(5S)-5-[[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperazin-1-yl]methyl]-2-oxo-1,3-oxazolidin-3-yl]-3H-1,3-benzoxazol-2-one Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)N1CCN(CC1)C[C@H]1CN(C(O1)=O)C1=CC2=C(NC(O2)=O)C=C1 CONKBQPVFMXDOV-QHCPKHFHSA-N 0.000 description 1
- 208000010444 Acidosis Diseases 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 239000004098 Tetracycline Substances 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- 230000007950 acidosis Effects 0.000 description 1
- 208000026545 acidosis disease Diseases 0.000 description 1
- 230000009056 active transport Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000000540 analysis of variance Methods 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 229960005069 calcium Drugs 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000031891 intestinal absorption Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 229940091250 magnesium supplement Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- HOVAGTYPODGVJG-ZFYZTMLRSA-N methyl alpha-D-glucopyranoside Chemical compound CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HOVAGTYPODGVJG-ZFYZTMLRSA-N 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 235000013384 milk substitute Nutrition 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229910000150 monocalcium phosphate Inorganic materials 0.000 description 1
- 235000019691 monocalcium phosphate Nutrition 0.000 description 1
- 239000002444 monopotassium citrate Substances 0.000 description 1
- 235000015861 monopotassium citrate Nutrition 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229960003531 phenolsulfonphthalein Drugs 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229960003975 potassium Drugs 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000001508 potassium citrate Substances 0.000 description 1
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 description 1
- WKZJASQVARUVAW-UHFFFAOYSA-M potassium;hydron;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [K+].OC(=O)CC(O)(C(O)=O)CC([O-])=O WKZJASQVARUVAW-UHFFFAOYSA-M 0.000 description 1
- 208000026775 severe diarrhea Diseases 0.000 description 1
- 229940083542 sodium Drugs 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229940040944 tetracyclines Drugs 0.000 description 1
- 235000015870 tripotassium citrate Nutrition 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1241876 | 1976-03-27 | ||
| GB1241876 | 1976-03-27 | ||
| GB1241776 | 1976-03-27 | ||
| GB1241776A GB1581826A (en) | 1976-03-27 | 1976-03-27 | Veterinary compositions for treating diarrhoea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK134377A DK134377A (da) | 1977-09-28 |
| DK166430B1 true DK166430B1 (da) | 1993-05-24 |
Family
ID=26249005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK134377A DK166430B1 (da) | 1976-03-27 | 1977-03-25 | Fremgangsmaade til fremstilling af et monosaccharidholdigt praeparat |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4164568A (enExample) |
| AU (1) | AU510209B2 (enExample) |
| CA (1) | CA1075157A (enExample) |
| DE (1) | DE2712786A1 (enExample) |
| DK (1) | DK166430B1 (enExample) |
| FR (1) | FR2345155A1 (enExample) |
| HK (1) | HK62984A (enExample) |
| IE (1) | IE45026B1 (enExample) |
| NL (1) | NL184666C (enExample) |
| NZ (1) | NZ183492A (enExample) |
| ZA (1) | ZA771409B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA786856B (en) * | 1977-12-23 | 1979-11-28 | Beecham Group Ltd | Oral formulations for human use |
| EP0086428B1 (en) * | 1979-08-23 | 1987-07-29 | Beecham Group Plc | Antidiarrhoea veterinary composition, its production and oral doser containing it |
| FR2467599B1 (fr) * | 1979-10-24 | 1983-07-29 | Agronomique Inst Nat Rech | Nouvelles compositions rehydratantes utiles notamment dans le traitement de la diarrhee chez le veau |
| US4574085A (en) * | 1981-05-15 | 1986-03-04 | Baxter Travenol Laboratories, Inc. | Method for using dialysis solution containing glycerol |
| EP0114104B1 (en) * | 1983-01-13 | 1989-04-19 | Colorado State University Research Foundation | An oral energy-rich composition and solution for combatting diarrhea in mammals |
| US4689319A (en) * | 1983-01-13 | 1987-08-25 | Colorado State University Research Foundation | Oral energy rich therapy for diarrhea in mammals |
| US5038396A (en) * | 1983-10-03 | 1991-08-06 | Mogens Gjerlov | Preparation for rehydrating monogastric animals, including new-born calves, pigs and human beings suffering from diarrhoea and use thereof |
| DK454683D0 (da) * | 1983-10-03 | 1983-10-03 | Mogens Gjerloev | Tarmreguleringsmiddel til behandling af diarre hos dyr samt anvendelse heraf |
| AU571011B2 (en) * | 1983-10-07 | 1988-03-31 | State Of Victoria, The | Treatment of neonatal calf diarrhoea |
| US4839347A (en) * | 1984-11-29 | 1989-06-13 | Techmix, Inc. | Composition for treating dehydration |
| FR2574295B1 (fr) * | 1984-12-07 | 1988-02-26 | Rech Etu Therapeutiques | Medicaments a base de gluconate de zinc utiles pour le traitement des hyperprolactinemies |
| ES2038122T3 (es) * | 1985-11-18 | 1993-07-16 | Beecham Group Plc | Un procedimiento para la preparacion de una composicion veterinaria2. |
| FR2613228A1 (fr) * | 1987-03-30 | 1988-10-07 | Agronomique Inst Nat Rech | Composition rehydratante a base de glucose utile notamment dans le traitement des etats diarrheiques et des etats de chocs chez le veau |
| AU634746B2 (en) * | 1989-02-07 | 1993-03-04 | Dimminaco Ag/Sa/Ltd. | Effervescent composition for oral rehydration |
| WO1994002847A1 (en) * | 1992-07-27 | 1994-02-03 | Invitro International | In vitro test for dermal corrosive properties |
| US5962733A (en) * | 1996-09-25 | 1999-10-05 | Vets Plus, Inc. | Glutamine containing electrolyte solution for calf scours |
| US6066341A (en) * | 1999-03-15 | 2000-05-23 | Farnam Companies, Inc. | Composition for the treatment of scours in calves |
| CN1409629A (zh) * | 1999-10-19 | 2003-04-09 | 藤泽药品工业株式会社 | 动物的育肥促进剂及育肥促进方法 |
| US6365152B1 (en) | 2001-03-15 | 2002-04-02 | Bovine Health Products, Inc. | Scours treatment and method of making same |
| DK175877B1 (da) * | 2002-11-11 | 2005-05-09 | Pharmalett As | Præparater til anvendelse som terapeutisk middel |
| US20060039899A1 (en) * | 2004-08-23 | 2006-02-23 | Winn Robert T | Animal nutritional product that increases weight gain and reduces diarrhea morbidity, mortality and severity by stimulation of natural immune response, nutritional support of immune function and supplemental nutricines and probiotics |
| US20070160683A1 (en) | 2006-01-12 | 2007-07-12 | Land O'lakes Purina Feed Llc | Electrolyte supplement and method of use |
| DK2178391T3 (da) | 2007-07-09 | 2014-08-25 | Hills Pet Nutrition Inc | Sammensætninger og fremgangsmåder til at ændre afføringskvaliteten hos et dyr |
| US8529965B2 (en) | 2007-07-09 | 2013-09-10 | Hill's Pet Nutrition, Inc. | Compositions and methods for altering stool quality in an animal |
| RU2444907C2 (ru) * | 2007-07-09 | 2012-03-20 | Хилл'С Пет Ньютришн, Инк. | Композиция корма, набор и способ изменения качества стула у животного (варианты) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2333950A (en) * | 1940-12-19 | 1943-11-09 | Gen Foods Corp | Therapeutic pectous product |
| US3080234A (en) * | 1960-12-06 | 1963-03-05 | Pfizer & Co C | Method of improving the efficiency of amino acid diets |
| US3362879A (en) * | 1965-01-11 | 1968-01-09 | Health Education Welfare Usa | Tyrosine tranquilizing compositions and methods of treatment |
| US3360434A (en) * | 1965-03-22 | 1967-12-26 | Udenfriend Sidney | Method for reducing blood pressure with phenylalanine derivatives |
| US3337404A (en) * | 1965-06-28 | 1967-08-22 | Merck & Co Inc | Effervescent potassium composition |
| US3743744A (en) * | 1972-02-29 | 1973-07-03 | Schering Corp | Means for inhibiting scours in piglets by administering a source of citrate ions |
| US3928574A (en) * | 1973-03-27 | 1975-12-23 | Univ Colorado State Res Found | Method and composition for treating diarrhea in mammals |
| US3898328A (en) * | 1973-12-03 | 1975-08-05 | Syntex Inc | Dry stable composition for the treatment of scours and dehydration |
| US4042684A (en) * | 1976-03-23 | 1977-08-16 | Annika Britt Kahm | Dietetic beverage |
-
1977
- 1977-03-03 NZ NZ183492A patent/NZ183492A/xx unknown
- 1977-03-08 ZA ZA00771409A patent/ZA771409B/xx unknown
- 1977-03-11 US US05/776,536 patent/US4164568A/en not_active Expired - Lifetime
- 1977-03-17 CA CA274,190A patent/CA1075157A/en not_active Expired
- 1977-03-18 FR FR7708150A patent/FR2345155A1/fr active Granted
- 1977-03-23 DE DE19772712786 patent/DE2712786A1/de active Granted
- 1977-03-23 NL NLAANVRAGE7703128,A patent/NL184666C/xx not_active IP Right Cessation
- 1977-03-24 AU AU23619/77A patent/AU510209B2/en not_active Expired
- 1977-03-25 DK DK134377A patent/DK166430B1/da not_active IP Right Cessation
- 1977-03-25 IE IE635/77A patent/IE45026B1/en not_active IP Right Cessation
-
1984
- 1984-08-09 HK HK629/84A patent/HK62984A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL184666C (nl) | 1989-10-02 |
| IE45026L (en) | 1977-09-27 |
| NL184666B (nl) | 1989-05-01 |
| HK62984A (en) | 1984-08-17 |
| NZ183492A (en) | 1980-04-28 |
| AU510209B2 (en) | 1980-06-12 |
| DK134377A (da) | 1977-09-28 |
| ZA771409B (en) | 1978-02-22 |
| NL7703128A (nl) | 1977-09-29 |
| FR2345155B1 (enExample) | 1980-02-01 |
| CA1075157A (en) | 1980-04-08 |
| DE2712786C2 (enExample) | 1989-05-18 |
| US4164568A (en) | 1979-08-14 |
| IE45026B1 (en) | 1982-06-02 |
| DE2712786A1 (de) | 1977-09-29 |
| AU2361977A (en) | 1978-09-28 |
| FR2345155A1 (fr) | 1977-10-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK166430B1 (da) | Fremgangsmaade til fremstilling af et monosaccharidholdigt praeparat | |
| DK167899B1 (da) | Veterinaerpraeparat | |
| US5028437A (en) | Treatment of animal diarrhoea | |
| Thatcher et al. | Tolerance to potassium intoxication in the albino rat | |
| DE69527140T2 (de) | Wirkstoff zur prävention oder behandlung von osteoporose | |
| Heyman et al. | Protective action of glycine in cisplatin nephrotoxicity | |
| Brownie et al. | Teratogenic effect of calcium edetate (CaEDTA) in rats and the protective effect of zinc | |
| US3769399A (en) | Intestinal bile acid binding process and compositions | |
| Carlson et al. | Toxicity studies on hydroquinone. | |
| Rickert et al. | Distribution of polybrominated biphenyls after dietary exposure in pregnant and lactating rats and their offspring | |
| Alcock et al. | Thymic changes in the magnesium-depleted rat | |
| Hoffeld et al. | Adverse effects on offspring of tranquillizing drugs during pregnancy | |
| Herman et al. | Effect of bound gossypol on the absorption of iron by rats | |
| Bray et al. | Decrease in bone density in young male guinea pigs fed high levels of ascorbic acid | |
| Mark-Savage et al. | Reduction by copper supplementation of teratogenic effects of D-penicillamine | |
| Bixler et al. | Retention of fluoride in soft tissues of chickens receiving different fat diets | |
| Thacker | Effect of a physiological cation-anion imbalance on the growth and mineral nutrition of rabbits | |
| Anastasia et al. | General and histopathological results of a two-year study of rats fed semi-purified diets containing casein and soya protein | |
| Sugawara et al. | Cadmium accumulation in organs and mortality during a continued oral uptake | |
| Nelson et al. | Factors affecting the vitamin K requirement of the chick | |
| West et al. | Urinary excretion of phosphate following the injection of sodium p-aminohippurate | |
| Rohse et al. | Absorption of choline from intestinal loops in dogs | |
| GB1581826A (en) | Veterinary compositions for treating diarrhoea | |
| Gaster et al. | Differential Effects of Low Calcium Diets on the Bones of Mice and Rats/Unterschiedliche Wirkungen kalziumarmer Kostformen auf die Knochen bei Mäusen und Ratten/Différences d'effets des régimes bas en calcium sur les os des souris et de rats | |
| PT1400246E (pt) | Composições orais para o tratamento de mamíferos obesos, não diabéticos, incluindo seres humanos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired | ||
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |