DK1622936T3 - Fremgangsmåde til fremstilling af en N-terminalt modificeret kemotaktisk faktor - Google Patents

Fremgangsmåde til fremstilling af en N-terminalt modificeret kemotaktisk faktor

Info

Publication number
DK1622936T3
DK1622936T3 DK04739081T DK04739081T DK1622936T3 DK 1622936 T3 DK1622936 T3 DK 1622936T3 DK 04739081 T DK04739081 T DK 04739081T DK 04739081 T DK04739081 T DK 04739081T DK 1622936 T3 DK1622936 T3 DK 1622936T3
Authority
DK
Denmark
Prior art keywords
mcp
monocytes
agonist
producing
chemotactic factor
Prior art date
Application number
DK04739081T
Other languages
Danish (da)
English (en)
Inventor
Roman Necina
Randolph Seidler
Martin Lenter
Henri Doods
Robert Wandl
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of DK1622936T3 publication Critical patent/DK1622936T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/523Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Vascular Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK04739081T 2003-05-02 2004-04-13 Fremgangsmåde til fremstilling af en N-terminalt modificeret kemotaktisk faktor DK1622936T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03010014A EP1473304A1 (de) 2003-05-02 2003-05-02 Verfahren zur Herstellung eines N-terminal modifizierten chemotaktischen Faktors
PCT/EP2004/003856 WO2004096850A1 (de) 2003-05-02 2004-04-13 Verfahren zur herstellung eines n-terminal modifizierten chemotaktischen faktors

Publications (1)

Publication Number Publication Date
DK1622936T3 true DK1622936T3 (da) 2008-10-27

Family

ID=32981800

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04739081T DK1622936T3 (da) 2003-05-02 2004-04-13 Fremgangsmåde til fremstilling af en N-terminalt modificeret kemotaktisk faktor

Country Status (20)

Country Link
EP (2) EP1473304A1 (ko)
JP (1) JP2007535891A (ko)
KR (1) KR20050121751A (ko)
CN (1) CN1784420A (ko)
AT (1) ATE398631T1 (ko)
AU (1) AU2004233964A1 (ko)
BR (1) BRPI0410023A (ko)
CA (1) CA2524270A1 (ko)
CO (1) CO5640145A2 (ko)
DE (1) DE502004007394D1 (ko)
DK (1) DK1622936T3 (ko)
ES (1) ES2309528T3 (ko)
MX (1) MXPA05011700A (ko)
PL (1) PL1622936T3 (ko)
PT (1) PT1622936E (ko)
RU (1) RU2005137356A (ko)
SI (1) SI1622936T1 (ko)
UA (1) UA83661C2 (ko)
WO (1) WO2004096850A1 (ko)
ZA (1) ZA200507702B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008002101A (es) 2005-08-12 2008-04-19 Schering Corp Fusiones de la proteina-1 quimiotactica de monocito.
US8524217B2 (en) 2010-05-11 2013-09-03 Merck Sharp & Dohme Corp. MCP1-Ig fusion variants

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92937A0 (en) * 1989-01-31 1990-09-17 Us Health Human derived monocyte attracting protein,pharmaceutical compositions comprising it and dna encoding it
US6869924B1 (en) * 1989-01-31 2005-03-22 The United States Of America As Represented By The Department Of Health And Human Services Human derived monocyte attracting purified protein product useful in a method of treating infection and neoplasms in a human body, and the cloning of full length cDNA thereof
WO1999005279A1 (en) * 1997-07-25 1999-02-04 Zeneca Limited Mcp-1 analogs

Also Published As

Publication number Publication date
EP1622936A1 (de) 2006-02-08
DE502004007394D1 (de) 2008-07-31
PT1622936E (pt) 2008-08-08
UA83661C2 (ru) 2008-08-11
ATE398631T1 (de) 2008-07-15
SI1622936T1 (sl) 2008-12-31
EP1473304A1 (de) 2004-11-03
BRPI0410023A (pt) 2006-04-25
RU2005137356A (ru) 2006-06-10
CA2524270A1 (en) 2004-11-11
ES2309528T3 (es) 2008-12-16
ZA200507702B (en) 2007-02-28
MXPA05011700A (es) 2006-01-23
AU2004233964A1 (en) 2004-11-11
CO5640145A2 (es) 2006-05-31
EP1622936B1 (de) 2008-06-18
WO2004096850A1 (de) 2004-11-11
JP2007535891A (ja) 2007-12-13
KR20050121751A (ko) 2005-12-27
CN1784420A (zh) 2006-06-07
PL1622936T3 (pl) 2008-11-28

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