DK158544C - Lysinsalt af gadolinium-dota kompleks og diagnostisk middel indeholdende saltet - Google Patents

Lysinsalt af gadolinium-dota kompleks og diagnostisk middel indeholdende saltet

Info

Publication number
DK158544C
DK158544C DK625987A DK625987A DK158544C DK 158544 C DK158544 C DK 158544C DK 625987 A DK625987 A DK 625987A DK 625987 A DK625987 A DK 625987A DK 158544 C DK158544 C DK 158544C
Authority
DK
Denmark
Prior art keywords
salt
lydal
gadolinium
diagnostic agents
agents containing
Prior art date
Application number
DK625987A
Other languages
English (en)
Other versions
DK625987A (da
DK625987D0 (da
DK158544B (da
Inventor
Bruno Bonnemain
Jean Lautrou
Dominique Meyer
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of DK625987A publication Critical patent/DK625987A/da
Publication of DK625987D0 publication Critical patent/DK625987D0/da
Publication of DK158544B publication Critical patent/DK158544B/da
Application granted granted Critical
Publication of DK158544C publication Critical patent/DK158544C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK625987A 1986-04-11 1987-11-27 Lysinsalt af gadolinium-dota kompleks og diagnostisk middel indeholdende saltet DK158544C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8605235 1986-04-11
FR8605235A FR2596992B1 (fr) 1986-04-11 1986-04-11 Sel de lysine du complexe gadolinium-dota et ses applications au diagnostic
PCT/FR1987/000114 WO1987006229A1 (fr) 1986-04-11 1987-04-07 Sel de lysine du complexe gadolinium-dota et ses applications au diagnostic
FR8700114 1987-04-07

Publications (4)

Publication Number Publication Date
DK625987A DK625987A (da) 1987-11-27
DK625987D0 DK625987D0 (da) 1987-11-27
DK158544B DK158544B (da) 1990-06-05
DK158544C true DK158544C (da) 1990-11-05

Family

ID=9334161

Family Applications (1)

Application Number Title Priority Date Filing Date
DK625987A DK158544C (da) 1986-04-11 1987-11-27 Lysinsalt af gadolinium-dota kompleks og diagnostisk middel indeholdende saltet

Country Status (8)

Country Link
US (1) US4877600A (da)
EP (1) EP0263861B1 (da)
JP (1) JPH07113032B2 (da)
AU (1) AU591774B2 (da)
DK (1) DK158544C (da)
FI (1) FI84071C (da)
FR (1) FR2596992B1 (da)
WO (1) WO1987006229A1 (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648063A (en) * 1981-07-24 1997-07-15 Schering Aktiengesellschaft Sterile composition comprising a chelate complex for magnetic resonance imaging
MX174467B (es) * 1986-01-23 1994-05-17 Squibb & Sons Inc 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos
US5271927A (en) * 1986-02-13 1993-12-21 Celltech Limited Antibody conjugates with macrocyclic ligands
IT1224416B (it) * 1987-12-24 1990-10-04 Bracco Ind Chimica Spa Chelanti macrociclici e loro chelati
US5049667A (en) * 1987-04-14 1991-09-17 Guerbet S.A. Nitrogen-containing cyclic ligands
FR2637895B1 (fr) * 1988-10-14 1992-11-06 Guerbet Sa Nouveaux ligands cycliques azotes, complexes metalliques formes par ces ligands, compositions de diagnostic contenant ces complexes et procede de preparation des ligands
DE3713842A1 (de) * 1987-04-22 1988-11-17 Schering Ag Substituierte cyclische komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel
US5130437A (en) * 1987-05-08 1992-07-14 Salutar, Inc. N,N'-bis-(pyridoxal)ethylenediamine-N,N'-diacetic acid derivatives
US4994259A (en) * 1987-05-08 1991-02-19 Salutar, Inc. Improvement in the method of NMR imaging employing a manganese II chelates of N,N'-bis[pyridoxal-alkylene (or cycloalkylene) (or arylene)]-N,N'-diacetic acid derivatives
US5198208A (en) * 1987-07-16 1993-03-30 Nycomed Imaging As Aminopolycarboxylic acids and derivatives thereof
GB8719041D0 (en) * 1987-08-12 1987-09-16 Parker D Conjugate compounds
GB8719042D0 (en) * 1987-08-12 1987-09-16 Parker D Conjugate compounds
US5314681A (en) * 1988-12-23 1994-05-24 Nycomed Innovation Ab Composition of positive and negative contrast agents for electron spin resonance enhanced magnetic resonance imaging
DE69024826T2 (de) * 1989-02-10 1996-06-27 Celltech Therapeutics Ltd Aza-Macrozyklen und Verfahren zu deren Herstellung
US5342936A (en) * 1989-02-10 1994-08-30 David Parker Tetra-aza macrocycles and processes for their preparation
US6139603A (en) * 1989-02-22 2000-10-31 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Process for recovering oxygen
US5247077A (en) * 1989-06-23 1993-09-21 Celltech Limited Tri-aza macrocycles and processes for their preparation
FR2654344B1 (fr) * 1989-11-16 1994-09-23 Cis Bio Int Complexe paramagnetique de gadolinium, son procede de preparation et son utilisation pour le diagnostic par irm.
US5516503A (en) * 1989-11-16 1996-05-14 Guerbet S.A. Diagnostic composition comprising a binuclear complex, its method of preparation and its use in magnetic resonance imaging
US5684135A (en) * 1990-04-18 1997-11-04 Celltech Therapeutics Limited Conjugate compounds containing aza-macro-cycles and processes for their preparation
DE69124132T2 (de) * 1990-04-18 1997-06-05 Celltech Therapeutics Ltd Tetra-aza-makrozyklen, Verfahren zu ihrer Herstellung und ihre Anwendung in NMR-Bildformung
US5480990A (en) * 1991-12-10 1996-01-02 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes for use as contrast agents
US5739294A (en) * 1991-12-10 1998-04-14 The Dow Chemical Company Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents
IT1283218B1 (it) * 1996-03-08 1998-04-16 Bracco Spa Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi
US20060014938A1 (en) * 2004-07-14 2006-01-19 Groman Ernest V Stable aqueous colloidal lanthanide oxides
EP1999118B1 (en) 2006-03-14 2012-10-17 Mallinckrodt LLC Metal complexes of tetraazamacrocycle derivatives
FR2921271A1 (fr) * 2007-09-20 2009-03-27 Guerbet Sa Formulation d'agents de contraste pour l'irm contenant une polybase organique
US20090208421A1 (en) 2008-02-19 2009-08-20 Dominique Meyer Process for preparing a pharmaceutical formulation of contrast agents
ES2617741T3 (es) 2009-04-10 2017-06-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Fucoidanos como ligandos para el diagnóstico de patologías degenerativas
GB201102189D0 (en) * 2011-02-08 2011-03-23 King S College London Materials and methods relating to cardiovascular imaging
EP3027228B1 (en) 2013-08-01 2024-10-02 Rochester Institute of Technology Modular imaging agents containing amino acids and peptides
AT516104B1 (de) * 2014-07-31 2016-08-15 Sanochemia Pharmazeutika Ag Verfahren zum Herstellen einer flüssigen pharmazeutischen Zubereitung
GB201522412D0 (en) * 2015-12-18 2016-02-03 Ge Healthcare As Dota synthesis
US10918742B2 (en) 2016-03-25 2021-02-16 Nanoprobes, Inc. Iodine-based particles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
AU574668B2 (en) * 1983-04-12 1988-07-14 Monarch Marking Systems Inc. Labeler

Also Published As

Publication number Publication date
EP0263861A1 (fr) 1988-04-20
JPH07113032B2 (ja) 1995-12-06
US4877600A (en) 1989-10-31
FI84071B (fi) 1991-06-28
FR2596992B1 (fr) 1988-12-16
FI875374A (fi) 1987-12-07
AU591774B2 (en) 1989-12-14
WO1987006229A1 (fr) 1987-10-22
FR2596992A1 (fr) 1987-10-16
DK625987A (da) 1987-11-27
EP0263861B1 (fr) 1990-08-01
DK625987D0 (da) 1987-11-27
JPS63503062A (ja) 1988-11-10
DK158544B (da) 1990-06-05
FI875374A0 (fi) 1987-12-07
FI84071C (fi) 1991-10-10
AU7235087A (en) 1987-11-09

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