DK156070C - Analogifremgangsmaade til fremstilling af antibiotisk aktive derivater af aminocyclitoler - Google Patents

Analogifremgangsmaade til fremstilling af antibiotisk aktive derivater af aminocyclitoler

Info

Publication number
DK156070C
DK156070C DK018675A DK18675A DK156070C DK 156070 C DK156070 C DK 156070C DK 018675 A DK018675 A DK 018675A DK 18675 A DK18675 A DK 18675A DK 156070 C DK156070 C DK 156070C
Authority
DK
Denmark
Prior art keywords
aminocyclitols
preparation
active derivatives
antibiotic active
analogy procedure
Prior art date
Application number
DK018675A
Other languages
Danish (da)
English (en)
Other versions
DK156070B (da
DK18675A (enrdf_load_stackoverflow
Inventor
John Jessen Wright
Peter John Lovell Daniels
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/452,586 external-priority patent/US4029882A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of DK18675A publication Critical patent/DK18675A/da
Publication of DK156070B publication Critical patent/DK156070B/da
Application granted granted Critical
Publication of DK156070C publication Critical patent/DK156070C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK018675A 1974-03-19 1975-01-22 Analogifremgangsmaade til fremstilling af antibiotisk aktive derivater af aminocyclitoler DK156070C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US45257174A 1974-03-19 1974-03-19
US45258674 1974-03-19
US45257174 1974-03-19
US05/452,586 US4029882A (en) 1974-03-19 1974-03-19 Selective acylation of the C-1 amino group of aminoglycoside antibiotics
CH1060174 1974-07-31
CH1060174 1974-07-31

Publications (3)

Publication Number Publication Date
DK18675A DK18675A (enrdf_load_stackoverflow) 1975-09-20
DK156070B DK156070B (da) 1989-06-19
DK156070C true DK156070C (da) 1989-11-06

Family

ID=27176473

Family Applications (1)

Application Number Title Priority Date Filing Date
DK018675A DK156070C (da) 1974-03-19 1975-01-22 Analogifremgangsmaade til fremstilling af antibiotisk aktive derivater af aminocyclitoler

Country Status (11)

Country Link
JP (1) JPS5843398B2 (enrdf_load_stackoverflow)
AT (1) AT341088B (enrdf_load_stackoverflow)
DD (1) DD117871A5 (enrdf_load_stackoverflow)
DK (1) DK156070C (enrdf_load_stackoverflow)
ES (1) ES433990A1 (enrdf_load_stackoverflow)
FI (1) FI60714C (enrdf_load_stackoverflow)
HU (1) HU175673B (enrdf_load_stackoverflow)
IT (1) IT1049348B (enrdf_load_stackoverflow)
LU (1) LU71687A1 (enrdf_load_stackoverflow)
NL (1) NL183826C (enrdf_load_stackoverflow)
NO (1) NO140426C (enrdf_load_stackoverflow)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2390255T3 (pl) * 2006-04-03 2017-01-31 Technion Research & Development Foundation Ltd. Nowe aminoglikozydy i ich zastosowania w leczeniu zaburzeń genetycznych

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780018A (en) * 1972-06-26 1973-12-18 Bristol Myers Co Derivatives of gentamicin c1
US3796698A (en) * 1972-10-18 1974-03-12 Bristol Myers Co Antibiotic derivatives of gentamicin c2
US3796699A (en) * 1972-11-06 1974-03-12 Bristol Myers Co Antibiotic derivatives of gentamicin c1a

Also Published As

Publication number Publication date
NO140426B (no) 1979-05-21
NO750168L (enrdf_load_stackoverflow) 1975-09-22
FI750141A7 (enrdf_load_stackoverflow) 1975-09-20
JPS5843398B2 (ja) 1983-09-27
FI60714C (fi) 1982-03-10
DD117871A5 (enrdf_load_stackoverflow) 1976-02-05
FI60714B (fi) 1981-11-30
AT341088B (de) 1978-01-25
DK156070B (da) 1989-06-19
IT1049348B (it) 1981-01-20
NO140426C (no) 1979-08-29
NL183826C (nl) 1989-02-01
DK18675A (enrdf_load_stackoverflow) 1975-09-20
NL7500690A (nl) 1975-09-23
LU71687A1 (enrdf_load_stackoverflow) 1975-12-09
ATA42975A (de) 1977-05-15
NL183826B (nl) 1988-09-01
HU175673B (hu) 1980-09-28
ES433990A1 (es) 1977-03-01
JPS50126640A (enrdf_load_stackoverflow) 1975-10-04

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PUP Patent expired