DK154092D0 - Imidazolforbindelser, deres fremstilling og anvendelse - Google Patents
Imidazolforbindelser, deres fremstilling og anvendelseInfo
- Publication number
- DK154092D0 DK154092D0 DK921540A DK154092A DK154092D0 DK 154092 D0 DK154092 D0 DK 154092D0 DK 921540 A DK921540 A DK 921540A DK 154092 A DK154092 A DK 154092A DK 154092 D0 DK154092 D0 DK 154092D0
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- alkoxy
- halogen
- amino
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polyesters Or Polycarbonates (AREA)
- Lubricants (AREA)
- Epoxy Resins (AREA)
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK921540A DK154092D0 (da) | 1992-12-23 | 1992-12-23 | Imidazolforbindelser, deres fremstilling og anvendelse |
AU52201/93A AU679697B2 (en) | 1992-12-23 | 1993-12-06 | Imidazole compounds, their preparation and use |
NZ250477A NZ250477A (en) | 1992-12-23 | 1993-12-16 | Heteroaryl or aryl substituted benzimidazole derivatives and pharmaceutical compositions |
DE69319413T DE69319413T2 (de) | 1992-12-23 | 1993-12-20 | Benzimidazolderivate, Verfahren zu deren Herstellung und Anwendung |
ZA939528A ZA939528B (en) | 1992-12-23 | 1993-12-20 | Imidazole compounds their preparation and use |
EP93610064A EP0604353B1 (de) | 1992-12-23 | 1993-12-20 | Benzimidazolderivate, Verfahren zu deren Herstellung und Anwendung |
AT93610064T ATE167862T1 (de) | 1992-12-23 | 1993-12-20 | Benzimidazolderivate, verfahren zu deren herstellung und anwendung |
CA002112081A CA2112081C (en) | 1992-12-23 | 1993-12-21 | Imidazole compounds, their preparation and use |
KR1019930028807A KR100310662B1 (ko) | 1992-12-23 | 1993-12-21 | 이미다졸화합물,이의제조방법및이를함유하는약제학적조성물 |
NO934474A NO304789B1 (no) | 1992-12-23 | 1993-12-22 | Imidazolforbindelser, farmas÷ytiske preparater som omfatter dem, og anvende av forbindelsene for fremstilling av medikamenter |
JP5324470A JPH06293742A (ja) | 1992-12-23 | 1993-12-22 | イミダゾール化合物とその製造及び使用方法 |
FI935801A FI111840B (fi) | 1992-12-23 | 1993-12-22 | Menetelmä uusien terapeuttisesti käyttökelpoisten 2-amino-bentsimidatsolien valmistamiseksi |
US08/172,427 US5441969A (en) | 1992-12-23 | 1993-12-22 | Imidazole compounds, their preparation and use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK921540A DK154092D0 (da) | 1992-12-23 | 1992-12-23 | Imidazolforbindelser, deres fremstilling og anvendelse |
Publications (1)
Publication Number | Publication Date |
---|---|
DK154092D0 true DK154092D0 (da) | 1992-12-23 |
Family
ID=8105880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK921540A DK154092D0 (da) | 1992-12-23 | 1992-12-23 | Imidazolforbindelser, deres fremstilling og anvendelse |
Country Status (13)
Country | Link |
---|---|
US (1) | US5441969A (de) |
EP (1) | EP0604353B1 (de) |
JP (1) | JPH06293742A (de) |
KR (1) | KR100310662B1 (de) |
AT (1) | ATE167862T1 (de) |
AU (1) | AU679697B2 (de) |
CA (1) | CA2112081C (de) |
DE (1) | DE69319413T2 (de) |
DK (1) | DK154092D0 (de) |
FI (1) | FI111840B (de) |
NO (1) | NO304789B1 (de) |
NZ (1) | NZ250477A (de) |
ZA (1) | ZA939528B (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5496826A (en) * | 1994-09-02 | 1996-03-05 | Bristol-Myers Squibb Company | Pharmaceutical methods of using heterocyclic derivatives of N-phenylamides |
US5821370A (en) * | 1994-10-24 | 1998-10-13 | Eli Lilly And Company | Heterocyclic compounds and their preparation and use |
US5891885A (en) * | 1996-10-09 | 1999-04-06 | Algos Pharmaceutical Corporation | Method for treating migraine |
DE19812059C1 (de) * | 1998-03-19 | 1999-09-23 | Wella Ag | Diaminobenzol-Derivate sowie diese Diaminobenzol-Derivate enthaltende Haarfärbemittel |
US6194447B1 (en) | 1998-07-02 | 2001-02-27 | Neurosearch A/S | Bis (benzimidazole) derivatives serving as potassium blocking agents |
JP2002519412A (ja) * | 1998-07-02 | 2002-07-02 | ニューロサーチ、アクティーゼルスカブ | カリウムチャンネル遮断剤 |
US20030017175A1 (en) * | 2001-07-05 | 2003-01-23 | R.T. Alamo Ventures I, Inc. | Sublingual administration of dihydroergotamine for the treatment of migraine |
US20030198669A1 (en) * | 2001-07-05 | 2003-10-23 | R.T. Alamo Ventures I, Llc | Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine |
US6685951B2 (en) | 2001-07-05 | 2004-02-03 | R. T. Alamo Ventures I, Inc. | Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine |
US6903126B2 (en) | 2001-07-09 | 2005-06-07 | Schering Ag | 1-Aryl-2-N-, S- or O-substituted benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives |
DE10135050A1 (de) * | 2001-07-09 | 2003-02-06 | Schering Ag | 1-Ary1-2-N-, S- oder O-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate |
US7482366B2 (en) * | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
WO2004035056A1 (en) * | 2002-10-13 | 2004-04-29 | Neurosearch A/S | Use of skca channel blocking drugs for combating parkinson's disease |
DE10342503A1 (de) * | 2003-09-12 | 2005-04-14 | Merck Patent Gmbh | Benzyl-Benzimidazolylderivate |
JP2008189662A (ja) * | 2007-01-12 | 2008-08-21 | New Industry Research Organization | スフィンゴシン1リン酸による神経伝達物質の放出促進機能とその応用 |
EP2120875B1 (de) | 2007-02-11 | 2018-07-11 | Map Pharmaceuticals Inc. | Verfahren zur therapeutischen verabreichung von dhe zur schnellen linderung von migräne bei gleichzeitiger minimierung von nebenwirkungsprofilen |
WO2013016223A2 (en) | 2011-07-22 | 2013-01-31 | The University Of Chicago | Treatments for migraine and related disorders |
CA2895816C (en) | 2012-12-21 | 2021-02-23 | Map Pharmaceuticals, Inc. | 8'-hydroxy-dihydroergotamine compounds and compositions |
KR101472686B1 (ko) * | 2013-07-09 | 2014-12-16 | 씨제이헬스케어 주식회사 | 벤즈이미다졸 유도체의 제조방법 |
TWI731317B (zh) | 2013-12-10 | 2021-06-21 | 美商健臻公司 | 原肌球蛋白相關之激酶(trk)抑制劑 |
CN107231803B (zh) | 2014-12-18 | 2019-12-03 | 建新公司 | 原肌球蛋白相关激酶(trk)抑制剂的药物制剂 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3928177A1 (de) * | 1989-04-08 | 1991-02-28 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
US5196444A (en) * | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
NZ239540A (en) * | 1990-09-24 | 1993-11-25 | Neurosearch As | 1-phenyl benzimidazole derivatives and medicaments |
ATE163290T1 (de) * | 1991-06-24 | 1998-03-15 | Neurosearch As | Imidazol-verbindungen, verfahren zu ihrer herstellung und ihre anwendung |
US5210091A (en) * | 1991-06-24 | 1993-05-11 | Neurosearch A/S | Imidazole compounds and their use |
US5314903A (en) * | 1991-12-03 | 1994-05-24 | Neurosearch A/S | Benzimidazole compounds useful as calcium channel blockers |
-
1992
- 1992-12-23 DK DK921540A patent/DK154092D0/da not_active IP Right Cessation
-
1993
- 1993-12-06 AU AU52201/93A patent/AU679697B2/en not_active Ceased
- 1993-12-16 NZ NZ250477A patent/NZ250477A/en not_active IP Right Cessation
- 1993-12-20 ZA ZA939528A patent/ZA939528B/xx unknown
- 1993-12-20 DE DE69319413T patent/DE69319413T2/de not_active Expired - Lifetime
- 1993-12-20 AT AT93610064T patent/ATE167862T1/de not_active IP Right Cessation
- 1993-12-20 EP EP93610064A patent/EP0604353B1/de not_active Expired - Lifetime
- 1993-12-21 KR KR1019930028807A patent/KR100310662B1/ko not_active IP Right Cessation
- 1993-12-21 CA CA002112081A patent/CA2112081C/en not_active Expired - Fee Related
- 1993-12-22 NO NO934474A patent/NO304789B1/no unknown
- 1993-12-22 FI FI935801A patent/FI111840B/fi active
- 1993-12-22 JP JP5324470A patent/JPH06293742A/ja active Pending
- 1993-12-22 US US08/172,427 patent/US5441969A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR940013506A (ko) | 1994-07-15 |
US5441969A (en) | 1995-08-15 |
DE69319413T2 (de) | 1999-01-28 |
NZ250477A (en) | 1995-07-26 |
AU679697B2 (en) | 1997-07-10 |
AU5220193A (en) | 1994-07-07 |
ZA939528B (en) | 1994-08-08 |
NO934759L (no) | 1994-06-24 |
KR100310662B1 (ko) | 2001-12-28 |
NO934759D0 (no) | 1993-12-22 |
FI935801A (fi) | 1994-06-24 |
NO304789B1 (no) | 1999-02-15 |
EP0604353B1 (de) | 1998-07-01 |
CA2112081A1 (en) | 1994-06-24 |
ATE167862T1 (de) | 1998-07-15 |
FI111840B (fi) | 2003-09-30 |
JPH06293742A (ja) | 1994-10-21 |
DE69319413D1 (de) | 1998-08-06 |
EP0604353A1 (de) | 1994-06-29 |
FI935801A0 (fi) | 1993-12-22 |
CA2112081C (en) | 2005-02-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK154092D0 (da) | Imidazolforbindelser, deres fremstilling og anvendelse | |
DK0563001T3 (da) | Imidazolforbindelser, deres fremstilling og anvendelse | |
ZA929268B (en) | Imidazole compounds, their preparation and use. | |
BR9104632A (pt) | Composto,composicao farmaceutica,aplicacao do referido composto e processo para a preparacao do referido composto | |
DE69108195D1 (de) | Astaxanthin-Zwischenprodukte. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A0 | Application filed | ||
AHS | Application shelved for other reasons than non-payment | ||
PUP | Patent expired |