DK153839C - Fremgangsmaade til fremstilling af 5-((1-hydroxy-1-metyl)-aetyl)-1-metyl-2-nitroimidazol - Google Patents

Fremgangsmaade til fremstilling af 5-((1-hydroxy-1-metyl)-aetyl)-1-metyl-2-nitroimidazol

Info

Publication number
DK153839C
DK153839C DK012976A DK12976A DK153839C DK 153839 C DK153839 C DK 153839C DK 012976 A DK012976 A DK 012976A DK 12976 A DK12976 A DK 12976A DK 153839 C DK153839 C DK 153839C
Authority
DK
Denmark
Prior art keywords
methyl
nitroimidazole
hydroxy
ethyl
preparing
Prior art date
Application number
DK012976A
Other languages
English (en)
Other versions
DK153839B (da
DK12976A (da
Inventor
Alessandro Assandri
Giancarlo Lancini
Giancarlo Volpe
Bruno Cavalleri
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of DK12976A publication Critical patent/DK12976A/da
Publication of DK153839B publication Critical patent/DK153839B/da
Application granted granted Critical
Publication of DK153839C publication Critical patent/DK153839C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88Nitrogen atoms, e.g. allantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91Nitro radicals
DK012976A 1975-01-15 1976-01-14 Fremgangsmaade til fremstilling af 5-((1-hydroxy-1-metyl)-aetyl)-1-metyl-2-nitroimidazol DK153839C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1684/75A GB1480192A (en) 1975-01-15 1975-01-15 1-methyl-2-nitro-imidazole-5-methanol derivatives
GB168475 1975-01-15

Publications (3)

Publication Number Publication Date
DK12976A DK12976A (da) 1976-07-16
DK153839B DK153839B (da) 1988-09-12
DK153839C true DK153839C (da) 1989-04-10

Family

ID=9726232

Family Applications (1)

Application Number Title Priority Date Filing Date
DK012976A DK153839C (da) 1975-01-15 1976-01-14 Fremgangsmaade til fremstilling af 5-((1-hydroxy-1-metyl)-aetyl)-1-metyl-2-nitroimidazol

Country Status (29)

Country Link
US (1) US4041168A (da)
JP (1) JPS5195069A (da)
AR (1) AR207804A1 (da)
AT (1) ATA13576A (da)
AU (1) AU8787575A (da)
BE (1) BE837595A (da)
CA (1) CA1062716A (da)
CH (1) CH609050A5 (da)
DD (1) DD123744A5 (da)
DE (1) DE2600538C3 (da)
DK (1) DK153839C (da)
ES (1) ES444324A1 (da)
FI (1) FI753726A (da)
FR (1) FR2297623A1 (da)
GB (1) GB1480192A (da)
GR (1) GR59991B (da)
IE (1) IE42462B1 (da)
IL (1) IL48751A0 (da)
IN (1) IN141389B (da)
LU (1) LU74172A1 (da)
NL (1) NL175413C (da)
NO (1) NO760113L (da)
NZ (1) NZ179762A (da)
PL (1) PL98602B1 (da)
PT (1) PT64695B (da)
RO (1) RO69138A (da)
SE (1) SE422204B (da)
SU (1) SU576043A3 (da)
ZA (1) ZA758017B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395341A (en) * 1977-07-21 1983-07-26 G. D. Searle & Co. Use of metronidazole in oil recovery
EP0024023B2 (de) * 1979-08-11 1992-11-11 Bayer Ag Antimykotische Mittel mit höherer Freisetzung der Wirkstoffe
US4957918A (en) * 1988-06-09 1990-09-18 Leonard Bloom Topical treatment of blepharitis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3065133A (en) * 1956-09-28 1962-11-20 Rhone Poulenc Sa Imidazoles for the control of histomoniasis
GB1081263A (en) * 1963-11-27 1967-08-31 Merck & Co Inc 1-substituted-2-ª‡-hydroxymethyl-5-nitroimidazoles and their preparation
US3472864A (en) * 1964-03-18 1969-10-14 Merck & Co Inc 2-carbonyl-5-nitroimidazoles
NL124627C (da) * 1964-08-12
GB1051388A (da) * 1964-11-17
US3584007A (en) * 1968-09-16 1971-06-08 Merck & Co Inc Preparation of 1-substituted-2-hydroxymethyl - 5-nitroimidazoles employing chilorinated benzenes as the reaction medium
NL143227B (nl) * 1968-11-15 1974-09-16 Lepetit Spa Werkwijze ter bereiding van imidazoolderivaten met bactericide werking.
US3652579A (en) * 1969-06-26 1972-03-28 Hoffmann La Roche 1-methyl-2-substituted 5-nitroimidazoles
US3634446A (en) * 1969-10-06 1972-01-11 Hoffmann La Roche 1-methyl-2-isopropyl-5-nitroimidazole and water soluble salts thereof
DE2229248C3 (de) * 1971-07-30 1980-03-27 Gruppo Lepetit S.P.A., Mailand (Italien) 5-Iminomethyl-2-nitroimidazoI-Derivate und Verfahren zu deren Herstellung
US3828064A (en) * 1972-10-25 1974-08-06 Dow Chemical Co Method of preparing 1,5-disubstituted-2-nitroimidazoles

Also Published As

Publication number Publication date
NL175413B (nl) 1984-06-01
AU8787575A (en) 1977-06-30
FR2297623B1 (da) 1979-06-22
FI753726A (da) 1976-07-16
DE2600538C3 (de) 1979-01-18
JPS5195069A (en) 1976-08-20
JPS5729033B2 (da) 1982-06-19
SU576043A3 (ru) 1977-10-05
DK153839B (da) 1988-09-12
ATA13576A (de) 1978-07-15
IE42462L (en) 1976-07-15
GR59991B (en) 1978-03-28
ES444324A1 (es) 1977-05-01
PT64695A (fr) 1976-02-01
DD123744A5 (da) 1977-01-12
BE837595A (fr) 1976-07-15
NL7600284A (nl) 1976-07-19
NO760113L (da) 1976-07-16
DE2600538B2 (de) 1978-05-24
ZA758017B (en) 1976-12-29
US4041168A (en) 1977-08-09
SE422204B (sv) 1982-02-22
IN141389B (da) 1977-02-19
LU74172A1 (da) 1976-07-20
IE42462B1 (en) 1980-08-13
NZ179762A (en) 1978-06-02
PL98602B1 (pl) 1978-05-31
IL48751A0 (en) 1976-02-29
SE7600341L (sv) 1976-07-16
DK12976A (da) 1976-07-16
PT64695B (fr) 1977-08-10
GB1480192A (en) 1977-07-20
AR207804A1 (es) 1976-10-29
FR2297623A1 (fr) 1976-08-13
DE2600538A1 (de) 1976-07-22
NL175413C (nl) 1984-11-01
RO69138A (ro) 1982-03-24
CH609050A5 (da) 1979-02-15
CA1062716A (en) 1979-09-18

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PBP Patent lapsed