DK151965C - Analogifremgangsmaade til fremstilling af piperazinsubstituerede 3-alkyltheobrominforbindelser - Google Patents

Analogifremgangsmaade til fremstilling af piperazinsubstituerede 3-alkyltheobrominforbindelser

Info

Publication number
DK151965C
DK151965C DK342882A DK342882A DK151965C DK 151965 C DK151965 C DK 151965C DK 342882 A DK342882 A DK 342882A DK 342882 A DK342882 A DK 342882A DK 151965 C DK151965 C DK 151965C
Authority
DK
Denmark
Prior art keywords
chob
compounds
alkyltheobromine
piperazin
substituted
Prior art date
Application number
DK342882A
Other languages
English (en)
Other versions
DK342882A (da
DK151965B (da
Inventor
Colette Favier
Henri Pinhas
Serge Beranger
Jean-Claude Pascal
Original Assignee
Laroche Navarron Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laroche Navarron Sa filed Critical Laroche Navarron Sa
Publication of DK342882A publication Critical patent/DK342882A/da
Publication of DK151965B publication Critical patent/DK151965B/da
Application granted granted Critical
Publication of DK151965C publication Critical patent/DK151965C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK342882A 1981-07-31 1982-07-30 Analogifremgangsmaade til fremstilling af piperazinsubstituerede 3-alkyltheobrominforbindelser DK151965C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28884781 1981-07-31
US06/288,847 US4374837A (en) 1981-07-31 1981-07-31 Piperazine derivatives of theobromine

Publications (3)

Publication Number Publication Date
DK342882A DK342882A (da) 1983-02-01
DK151965B DK151965B (da) 1988-01-18
DK151965C true DK151965C (da) 1988-06-20

Family

ID=23108917

Family Applications (1)

Application Number Title Priority Date Filing Date
DK342882A DK151965C (da) 1981-07-31 1982-07-30 Analogifremgangsmaade til fremstilling af piperazinsubstituerede 3-alkyltheobrominforbindelser

Country Status (12)

Country Link
US (1) US4374837A (da)
EP (1) EP0071543B1 (da)
JP (1) JPS5826886A (da)
AT (1) ATE30324T1 (da)
AU (1) AU560432B2 (da)
CA (1) CA1223875A (da)
DE (1) DE3277505D1 (da)
DK (1) DK151965C (da)
ES (1) ES514553A0 (da)
IE (1) IE53692B1 (da)
NZ (1) NZ201437A (da)
ZA (1) ZA825528B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307395A1 (de) * 1982-03-02 1983-09-08 Eisai Co., Ltd., Tokyo Arzneimittel zur behandlung von schmerzen, fieber, gewebe- und/oder knochen- und gelenkentzuendungen mit einem gehalt an theobromin- oder theophyllinderivaten als aktivem bestandteil
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
US4558129A (en) * 1983-05-18 1985-12-10 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
US4810706A (en) * 1985-12-20 1989-03-07 Recherche Syntex Piperazine derivatives of theophylline and theobromine
US5817662A (en) * 1992-11-09 1998-10-06 Cell Therapeutics, Inc. Substituted amino alkyl compounds
US5340813A (en) * 1992-11-09 1994-08-23 Cell Therapeutics, Inc. Substituted aminoalkyl xanthine compounds
US6103730A (en) * 1994-03-24 2000-08-15 Cell Therapeutics, Inc. Amine substituted compounds
US5807861A (en) * 1994-03-24 1998-09-15 Cell Therapeutics, Inc. Amine substituted xanthinyl compounds
US5801182A (en) * 1994-03-24 1998-09-01 Cell Therapeutics, Inc. Amine substituted compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1133989A (en) * 1964-12-08 1968-11-20 Chugai Pharmaceutical Co Ltd Theophylline derivatives, their salts and process for preparing the same
DE1620576A1 (de) * 1966-11-25 1970-02-26 Troponwerke Dinklage & Co Verfahren zur Herstellung von Theophyllin- und Theobrominverbindungen
DE1966620A1 (de) * 1969-03-20 1973-05-24 Walter Dr Bestian Verfahren zur herstellung von dialkylxanthin-derivaten
GB1289287A (da) * 1969-03-28 1972-09-13
DE2963600D1 (en) * 1978-04-27 1982-10-28 Laroche Navarron Sa Piperazine methane imine derivatives, methods for their preparation and their therapeutical use
JPS55118488A (en) * 1979-03-05 1980-09-11 Eisai Co Ltd Theobromine derivative and its preparation
US4374835A (en) * 1980-01-31 1983-02-22 Laroche-Navarron, S.A. Piperazine derivatives of theophylline

Also Published As

Publication number Publication date
US4374837A (en) 1983-02-22
JPS5826886A (ja) 1983-02-17
DE3277505D1 (en) 1987-11-26
EP0071543B1 (en) 1987-10-21
IE821841L (en) 1983-01-31
EP0071543A1 (en) 1983-02-09
CA1223875A (en) 1987-07-07
IE53692B1 (en) 1989-01-18
ES8400430A1 (es) 1983-11-01
NZ201437A (en) 1985-12-13
ATE30324T1 (de) 1987-11-15
AU560432B2 (en) 1987-04-09
DK342882A (da) 1983-02-01
DK151965B (da) 1988-01-18
ES514553A0 (es) 1983-11-01
ZA825528B (en) 1984-03-28
AU8666382A (en) 1983-02-03

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Legal Events

Date Code Title Description
PBP Patent lapsed