DK151382A - Fremgangsmaade til fremstilling af acylerede benzothiophener - Google Patents

Fremgangsmaade til fremstilling af acylerede benzothiophener Download PDF

Info

Publication number
DK151382A
DK151382A DK151382A DK151382A DK151382A DK 151382 A DK151382 A DK 151382A DK 151382 A DK151382 A DK 151382A DK 151382 A DK151382 A DK 151382A DK 151382 A DK151382 A DK 151382A
Authority
DK
Denmark
Prior art keywords
benzothiophenes
acylated
procedure
preparation
acylated benzothiophenes
Prior art date
Application number
DK151382A
Other languages
Danish (da)
English (en)
Inventor
M K Peters
C D Jones
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/331,046 external-priority patent/US4380635A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK151382A publication Critical patent/DK151382A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK151382A 1981-04-03 1982-04-02 Fremgangsmaade til fremstilling af acylerede benzothiophener DK151382A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24633381A 1981-04-03 1981-04-03
US24633581A 1981-04-03 1981-04-03
US33104581A 1981-12-16 1981-12-16
US06/331,046 US4380635A (en) 1981-04-03 1981-12-16 Synthesis of acylated benzothiophenes

Publications (1)

Publication Number Publication Date
DK151382A true DK151382A (da) 1982-10-04

Family

ID=27500218

Family Applications (1)

Application Number Title Priority Date Filing Date
DK151382A DK151382A (da) 1981-04-03 1982-04-02 Fremgangsmaade til fremstilling af acylerede benzothiophener

Country Status (13)

Country Link
EP (1) EP0062505B1 (el)
BG (1) BG37378A3 (el)
DE (1) DE3264853D1 (el)
DK (1) DK151382A (el)
ES (1) ES511123A0 (el)
FI (1) FI821161L (el)
GB (1) GB2096608B (el)
GR (1) GR78364B (el)
HU (1) HU191084B (el)
IL (1) IL65379A0 (el)
PL (1) PL130584B1 (el)
PT (1) PT74693B (el)
RO (1) RO84584B (el)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4117512A1 (de) * 1991-05-25 1992-11-26 Schering Ag 2-phenylbenzo(b)furane und -thiophene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
TW366342B (en) 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
USRE39049E1 (en) 1992-07-28 2006-03-28 Eli Lilly And Company Methods for inhibiting bone loss
USRE38968E1 (en) 1992-07-28 2006-02-07 Eli Lilly And Company Methods for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl-4-[2-(piperidin-1-yl) ethoxyphenylimethanone hydrochloride
US5462949A (en) * 1993-12-21 1995-10-31 Eli Lilly And Company Methods of inhibiting fertility in women
US5478847A (en) 1994-03-02 1995-12-26 Eli Lilly And Company Methods of use for inhibiting bone loss and lowering serum cholesterol
CA2145614A1 (en) * 1994-03-31 1995-10-01 Jeffrey A. Dodge Intermediates and processes for preparing benzothiophene compounds
US5523416A (en) * 1994-07-22 1996-06-04 Eli Lilly And Company Process for preparing 3-(4-aminoethoxy-benzoyl) benzo (B)-thiophenes
US5631369A (en) * 1994-08-31 1997-05-20 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
US5731436A (en) * 1994-08-31 1998-03-24 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
US5629425A (en) * 1994-09-19 1997-05-13 Eli Lilly And Company Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene
CO4410190A1 (es) * 1994-09-19 1997-01-09 Lilly Co Eli 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO
IL132954A (en) * 1995-02-28 2002-02-10 Lilly Co Eli Derivatives of benzothiophene
US6395755B1 (en) * 1995-03-10 2002-05-28 Eli Lilly And Company Benzothiophene pharmaceutical compounds
WO1996032937A1 (en) * 1995-04-21 1996-10-24 Eli Lilly And Company Benzothiophenes with novel basic side chains
IL122127A (en) * 1995-06-07 2001-05-20 Lilly Co Eli Derivatives of sulfonic vinyl acids, process for their preparation and use in the synthesis of benzo [b]
US5606076A (en) * 1995-06-07 1997-02-25 Eli Lilly And Company Process for the synthesis of benzo[b]thiophenes
CA2249406A1 (en) * 1996-03-19 1997-09-25 Eli Lilly And Company Synthesis of 3-¬4-(2-aminoethoxy)-benzoyl|-2-aryl-6-hydroxy-benzo¬b|thiophenes
AR013321A1 (es) * 1996-09-25 2000-12-27 Lilly Co Eli Procedimiento para preparar 2-(4-alcoxifenil)-6-alcoxi-benzo[b]tiofenos.
US5916916A (en) * 1996-10-10 1999-06-29 Eli Lilly And Company 1-aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods
CN1254280A (zh) * 1997-04-30 2000-05-24 伊莱利利公司 用于制备取代的苯并[b]噻吩的区域选择性烷基化方法
CA2231013A1 (en) * 1997-04-30 1998-10-30 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceuticals
JP2001524114A (ja) * 1997-04-30 2001-11-27 イーライ・リリー・アンド・カンパニー ベンゾ［ｂ］チオフェン類の製造における中間体および方法
CA2236254A1 (en) * 1997-04-30 1998-10-30 David Warren Hoard Process for preparing benzo¬b|thiophenes
JP2001523253A (ja) * 1997-04-30 2001-11-20 イーライ・リリー・アンド・カンパニー ベンゾ［ｂ］チオフェン類の製造のための中間体および方法
AU7261398A (en) * 1997-04-30 1998-11-24 Eli Lilly And Company Processes for preparing benzothiophenes
AU2003266940B2 (en) 2002-09-30 2007-02-08 A/S Gea Farmaceutisk Fabrik Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these
IT1403083B1 (it) * 2010-10-25 2013-10-04 Fidia Farmaceutici Nuova forma polimorfa di raloxifene cloridrato

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947470A (en) * 1974-06-20 1976-03-30 Smithkline Corporation Substituted benzofurans and benzothiophenes
US4001426A (en) * 1974-10-17 1977-01-04 Smithkline Corporation Substituted benzofurans and benzothiophenes
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents

Also Published As

Publication number Publication date
EP0062505A1 (en) 1982-10-13
FI821161A0 (fi) 1982-04-02
EP0062505B1 (en) 1985-07-24
GR78364B (el) 1984-09-26
RO84584B (ro) 1984-09-30
PT74693B (en) 1985-01-08
PL235751A1 (el) 1982-11-22
ES8304116A1 (es) 1983-02-16
PT74693A (en) 1982-05-01
HU191084B (en) 1987-01-28
BG37378A3 (en) 1985-05-15
FI821161L (fi) 1982-10-04
PL130584B1 (en) 1984-08-31
GB2096608A (en) 1982-10-20
GB2096608B (en) 1985-06-12
DE3264853D1 (en) 1985-08-29
RO84584A (ro) 1984-07-17
ES511123A0 (es) 1983-02-16
IL65379A0 (en) 1982-05-31

Similar Documents

Publication Publication Date Title
DK151382A (da) Fremgangsmaade til fremstilling af acylerede benzothiophener
DK160815C (da) Fremgangsmaade til fremstilling af faeldningskiselsyrer
DK2281A (da) Fremgangsmaade til fremstilling af tiazolinderivater
DK65882A (da) Fremgangsmaade til fremstilling af substituerede phosphonamider
DK300981A (da) Fremgangsmaade til fremstilling af imidazolderivater
DK435181A (da) Fremgangsmaade til fremstilling af thiazol-derivater
DK161581A (da) Fremgangsmaade til fremstilling af imidazolderivater
DK594585A (da) Fremgangsmaade til fremstilling af acylerede diketonforbindelser
DK100281A (da) Fremgangsmaade til fremstilling af imidazolderivater
DK161482A (da) Fremgangsmaade til fremstilling af et analgetisk praeparat
DK153282A (da) Fremgangsmaade til fremstilling af bismethinisoindoliner
DK239382A (da) Fremgangsmaade til fremstilling af anthracyclinglycosider
DK305982A (da) Fremgangsmaade til fremstilling af amidobenzamider
DK172181A (da) Fremgangsmaade til fremstilling af 9-carbamoyl-9-aminoalkylfluoren-derivater
DK364481A (da) Fremgangsmaade til fremstilling af caprylolactamer
DK449981A (da) Fremgangsmaade til fremstilling af acylderivater
DK309282A (da) Fremgangsmaade til fremstilling af et analgetisk praeparat
DK392082A (da) Fremgangsmaade til fremstilling af antibiotiket nosiheptid
DK296281A (da) Fremgangsmaade til fremstilling af aminocyklopentanonamider
DK448981A (da) Fremgangsmaade til fremstilling af 4-chinolinmethanderivater
DK424781A (da) Fremgangsmaade til fremstilling af quinolonderivater
DK579181A (da) Fremgangsmaade til fremstilling af diarylthiophener
DK4081A (da) Fremgangsmaade til fremstilling af acylderivater
DK153841C (da) Fremgangsmaade til fremstilling af ranitidin
DK12581A (da) Fremgangsmaade til fremstilling af kijanimicin

Legal Events

Date Code Title Description
ATS Application withdrawn
PBP Patent lapsed