DK147254B - MANUALLY USED RINSE RINSE APPLIANCE IN A MICRO TEST PLATE - Google Patents

MANUALLY USED RINSE RINSE APPLIANCE IN A MICRO TEST PLATE Download PDF

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Publication number
DK147254B
DK147254B DK503381A DK503381A DK147254B DK 147254 B DK147254 B DK 147254B DK 503381 A DK503381 A DK 503381A DK 503381 A DK503381 A DK 503381A DK 147254 B DK147254 B DK 147254B
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Denmark
Prior art keywords
liquid supply
wells
rinse
suction
duct
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DK503381A
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Danish (da)
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DK503381A (en
Inventor
Joergen Cappelen
Boerge Nielsen
Original Assignee
Nunc As
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Application filed by Nunc As filed Critical Nunc As
Priority to DK503381A priority Critical patent/DK147254B/en
Priority to NO822317A priority patent/NO151919B/en
Priority to AT82110470T priority patent/ATE20196T1/en
Priority to CA000415477A priority patent/CA1181319A/en
Priority to JP57198787A priority patent/JPS5892486A/en
Priority to DE8282110470T priority patent/DE3271585D1/en
Priority to EP82110470A priority patent/EP0080134B1/en
Publication of DK503381A publication Critical patent/DK503381A/en
Publication of DK147254B publication Critical patent/DK147254B/en

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/02Cleaning by the force of jets or sprays
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47LDOMESTIC WASHING OR CLEANING; SUCTION CLEANERS IN GENERAL
    • A47L17/00Apparatus or implements used in manual washing or cleaning of crockery, table-ware, cooking-ware or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L13/00Cleaning or rinsing apparatus
    • B01L13/02Cleaning or rinsing apparatus for receptacle or instruments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates

Abstract

A manually operable washer for simultaneously washing a number of wells of a multi well plate comprising a manifold (1) comprising a liquid supply channel (2) and a suction channel (3), said channels being connected with a number of liquid supply pipes (9) and suction pipes (18), respectively, each suction pipe (18) being mounted parallel with and adjacent to a liquid supply pipe (9), a valve through which the liquid supply channel (2) can be connected with a source of liquid, and means for connecting the suction channel (3) with a source of vacuum. The washer permits a quick and efficient selective washing of a number of wells of a multi well plate.

Description

1A72541A7254

Opfindelsen angår et manuelt betjeneligt skylleapparat til skylning af brønde i en mikrotestplade med en skyllevæske.BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a manually operated flushing apparatus for rinsing wells in a microtest plate with a rinsing fluid.

Der kendes automatiske s kyl leapparater til samtidig skylning af alle brøndene i mikrotestplader med en skyllevæske, såsom vand.Automatic cooling devices are known for simultaneously flushing all wells in microtest plates with a rinse liquid such as water.

5 Ved brug af sådanne mikrotestplader, der typisk omfatter 96 brønde anbragt i 8 rækker, hver omfattende 12 brønde, vil der i en forsøgsserie ofte kun blive anvendt nogle få rækker af brønde.Using such microtest plates, which typically comprise 96 wells placed in 8 rows, each comprising 12 wells, in a series of experiments, only a few rows of wells will often be used.

Ved brug af det kendte skylleapparat er det imidlertid ikke muligt at foretage en selektiv skylning af de pågældende brønde. Dette er en 10 væsentlig ulempe ved de kendte apparater, da de ikke anvendte men skyllede brønde normalt ikke vil kunne anvendes til nye forsøgs-serier, og da hele mikrotestpladen derfor må bortkastes efter brugen.However, using the known flushing apparatus, it is not possible to make a selective flushing of the wells in question. This is a major disadvantage of the known apparatus, since the unused but rinsed wells will not normally be usable for new test series, and therefore the entire microtest plate must be discarded after use.

Dette er navnlig en ulempe, hvis den anvendte mikrotestplade er belagt med et substrat og måske har gennemgået en lang behand-15 lingsprocedure.This is especially a disadvantage if the microtest plate used is coated with a substrate and may have undergone a long treatment procedure.

Som en alternativ løsning af det omtalte problem kunne man tænke sig en individuel skylning af hver brønd. Denne metode er imidlertid langsommelig og arbejdskrævende og kan medføre forsøgsfejl forårsaget af en uensartet skylning af brøndene. Der er derfor et 20 behov for at tilvejebringe et skylleapparat til samtidig og ensartet skylning af en del af brøndene i en plade, f.eks. en mikrotestplade bestående af et stort antal sammenbyggede brønde.As an alternative solution to the problem mentioned, an individual rinse of each well could be envisaged. However, this method is slow and labor-intensive and can lead to experimental errors caused by uneven flushing of the wells. Therefore, there is a need to provide a flushing apparatus for simultaneously and uniformly rinsing a portion of the wells in a plate, e.g. a microtest plate consisting of a large number of pooled wells.

Dette behov tilfredsstilles med skylleapparatet ifølge opfindelsen, hvilket skylleapparat er ejendommeligt ved, at det omfatter en 25 manifold omfattende en væsketilførselskanal og en sugekanal, hvor væsketilførselskanalen er forbundet med en enkelt række af parallelle væsketilførselsrør, og sugekanalen er forbundet med et tilsvarende antal sugerør, hvor hvert sugerør er anbragt parallelt med og i umiddelbar nærhed af et væsketilførselsrør, at væsketilførselskanalen 30 over en ventil er forbundet med organer til tilslutning af væsketilførselskanalen til en kilde for skyllevæske, og at sugekanalen er forbundet med organer til tilslutning af sugekanalen til en vakuumkilde.This need is satisfied by the rinse apparatus according to the invention, which is characterized in that it comprises a manifold comprising a liquid supply duct and a suction duct, wherein the liquid supply duct is connected to a single row of parallel liquid supply ducts and the suction duct is connected to a corresponding number of suction pipes. each suction pipe is arranged parallel to and in the immediate vicinity of a liquid supply pipe, that the liquid supply duct 30 is connected over a valve to means for connecting the liquid supply duct to a source of rinsing liquid and that the suction duct is connected to means for connecting the suction duct to a vacuum source.

Når skylleapparatet ifølge opfindelsen forbindes med en kil-35 de for skyllevæske, vil der ved påvirkning af den omtalte ventil ske en indføring af skyllevæske i væsketilførselsrørene og derved en samtidig udtømning af skyllevæske i de brønde, der skal skylles.When the flushing apparatus according to the invention is connected to a flushing fluid source, upon actuation of said valve, flushing fluid is introduced into the liquid supply tubes and thereby a simultaneous discharge of flushing liquid into the wells to be flushed.

Skylleapparatet ifølge opfindelsen holdes ved begyndelsen af en skylleproces fortrinsvis i en sådan højde over brøndene, at sugerø- 2 147254 renes nedre ender befinder sig i niveau med brøndenes øverste kan-ter, idet det herved sikres, at der ved tilførsel af overskud af skyl-levæske ikke strømmer væske fra en brønd til en anden. Når brøndene er blevet fyldt, lukkes for tilførslen af skyllevaske, og skylle-5 apparatet føres nedad, indtil sugerørenes nedre ender befinder sig umiddelbart over brøndenes bunde. Under denne bevægelse sker der en løbende udsugning af væske, og brøndene vil normalt være tømte, nir den nederste stilling nås. Skylleapparatet føres derpå op i udgangsstillingen, og processen gentages 2-3 gange.The flushing apparatus according to the invention is preferably held at the beginning of a flushing process at such a height above the wells that the lower ends of the suction tubes are level with the upper edges of the wells, thereby ensuring that by adding excess flushing to the wells. fluid does not flow fluid from one well to another. When the wells have been filled, the flushing sink is closed and the flushing apparatus is directed downwards until the lower ends of the suction tubes are immediately above the bottom of the wells. During this movement, a continuous extraction of liquid takes place, and the wells will usually be emptied when the lower position is reached. The flushing device is then brought up to its initial position and the process is repeated 2-3 times.

10 Enderne af sugerørene, der f.eks. består af rustfrit stål, er fortrinsvis anbragt i længere afstand fra blokken end enderne af væsketilførselsrørene, idet sugerørene deryed kan føres helt ned til bunden af rundbundede brønde uden at enderne af væsketilførselsrørene kommer i berøring med brøndenes skrå sider.The ends of the suction tubes, e.g. made of stainless steel, are preferably spaced further from the block than the ends of the liquid supply pipes, the suction pipes thereby being able to be routed all the way to the bottom of round bottom wells without contacting the ends of the liquid supply pipes with the inclined sides of the wells.

15 Manifolden består fortrinsvis af en blok, f.eks. en plast blok, hvori væsketilførselskanalen strækker sig parallelt med sugekanalen, og hvor væsketilførselsrørene, f.eks. tynde rør af rustfrit stål, er fastgjort i den nederste del af fordelingskanaler, der strækker sig fra blokkens overside gennem væsketilførselskanalen til blok-20 kens underside, hvorhos den øverste del af fordelingskanalerne er lukket med udtagelige lukkeorganer. De nævnte lukkeorganer er fortrinsvis skruer, såsom umbracoskruer, med udvendigt gevind, som svarer til et indvendigt gevind i fordelingskanalerne.The manifold preferably consists of a block, e.g. a plastic block in which the liquid supply duct extends parallel to the suction duct and wherein the liquid supply pipes, e.g. stainless steel thin tubes are fixed in the lower portion of distribution channels extending from the top of the block through the liquid supply channel to the underside of the block, the upper portion of the distribution channels being closed with removable closure means. Preferably, said closure means are screws, such as Allen screws, with external threads which correspond to an internal thread in the distribution channels.

Tilvejebringelsen af gennemgående fordelingskanaler frem-25 byder den særlige fordel, at der ved tilstopning af et væsketilførselsrør let kan foretages en rensning af røret, nemlig ved at fjerne skruen i den øverste del af den tilsvarende fordelingskanal og ved at føre en rensetråd ind i fordelingskanalen og væsketilførselsrøret.The provision of through-flow distribution channels provides the particular advantage that by clogging a fluid supply tube, a cleaning of the tube can be easily performed, namely by removing the screw in the upper portion of the corresponding distribution channel and by inserting a cleaning wire into the distribution channel and the liquid feed pipe.

Antallet af væsketilførselsrør kan vælges efter ønske, men 30 til brug i forbindelse med de ovenfor omtalte mikrotestplader anvendes fortrinsvis 8 eller 12 rør.The number of liquid delivery tubes can be selected as desired, but preferably 30 or 12 tubes for use with the above-mentioned microtest plates.

For at forhindre, at enderne af væsketilførselsrørene eller sugerørene kommer i berøring med bunden af brøndene, der skal skylles, eller med en eventuel belægning herpå, er der fortrinsvis 35 anbragt stopklodser på undersiden af manifoldblokken. Disse stopklodser består fortrinsvis af en fast cylindrisk kerne og en udskiftelig, omgivende bøsning.In order to prevent the ends of the fluid supply pipes or suction pipes from touching the bottom of the wells to be rinsed or with any coating thereon, 35 stop pads are preferably provided on the underside of the manifold block. These stop pads preferably consist of a fixed cylindrical core and a replaceable surrounding bush.

For at sikre, at bøsningen sidder fast på kernen, er der fortrinsvis anbragt en O-ring på kernens cylinderflade. Anvendelsen 147254 3 af en udskiftelig bøsning bevirker, at afstanden mellem brøndenes overkant og manifoldblokkens underside kan justeres i afhængighed af dybden af de brønde, der skal skylles.To ensure that the bushing is secured to the core, an O-ring is preferably provided on the cylinder surface of the core. The use of an interchangeable sleeve means that the distance between the top of the wells and the underside of the manifold block can be adjusted depending on the depth of the wells to be rinsed.

Ventilen, der tjener til at styre væsketilførslen til væsketil-5 førselskanalen, er fortrinsvis en fjederpåvirket ventil, som i hvilestillingen forhindrer tilstrømning af skyllevaske til væsketilførselskanalen, og som kan åbnes ved et let fingertryk. Ventilen er fortrinsvis anbragt i en gennemboring i manifoldblokken og holdes på plads heri ved hjælp af en bundskrue, der kan indskrues i denne gennemboring.The valve which serves to control the fluid supply to the liquid supply duct is preferably a spring-acting valve which prevents in the resting position the flow of flushing liquid to the liquid supply duct and which can be opened at a slight finger pressure. Preferably, the valve is disposed in a bore in the manifold block and held in place therein by a bottom screw which can be screwed into this bore.

10 Dette bevirker, at ventilen let kan udtages, og at såvel den bevægelige del af ventilen som udboringen let kan renses.This means that the valve can be easily removed and that both the movable part of the valve and the bore can be easily cleaned.

De nævnte organer til tilslutning af forbindelseskanalen til en kilde for skyllevaske og organerne til tilslutning af sugekanalen til en vakuumkilde er fortrinsvis rørstudse af plast, som er indsat i 15 kanaler i manifoldblokken.Said means for connecting the connecting duct to a flushing source and the means for connecting the suction duct to a vacuum source are preferably plastic pipe nozzles which are inserted into 15 ducts in the manifold block.

En yderligere fordel ved skylleapparatet ifølge opfindelsen er, at der ved tilstopning af væsketilførselskanalsystemet let kan foretages en rensning af kanalsystemet ved at forbinde fødestudsen med vakuumkilden.A further advantage of the flushing apparatus according to the invention is that by clogging the liquid supply duct system, a cleaning of the duct system can be easily performed by connecting the feeder nozzle to the vacuum source.

20 Som vakuumkilde kan der f.eks. anvendes en vandluftpum- pe.As a source of vacuum, e.g. a water air pump is used.

Opfindelsen skal herefter beskrives nærmere under henvisning til tegningen, hvor fig. 1 viser en udførelsesform for et skylleapparat 25 ifølge opfindelsen, set fra oven, fig. 2 viser et snit efter linien Il-Il gennem skylleapparatet, der er vist i fig. 1 men med ventilarrangementet fjernet, fig. 3 viser et snit efter linien I Il-Il I gennem skylleap-30 paratet, der er vist i fig. 1, og fig. 4 viser et lodret snitbillede i forstørret målestok af ventilen og en del af den omgivende blok i skylleapparatet, der er illustreret i fig. 1-3.The invention will now be described in more detail with reference to the drawing, in which fig. 1 is a top view of an embodiment of a flushing apparatus 25 according to the invention; FIG. 2 shows a section along the line II-II through the rinsing apparatus shown in FIG. 1 but with the valve arrangement removed; FIG. 3 is a sectional view taken on the line I-II-I through the rinsing apparatus shown in FIG. 1, and FIG. 4 is an enlarged vertical sectional view of the valve and a portion of the surrounding block of the flushing apparatus illustrated in FIG. 1-3.

Det på tegningen illustrerede skylleapparat består af en 35 manifold i form af en aflang blok 1, hvori der er udformet to langsgående kanaler, nemlig en væsketilførselskanal 2 og en sugekanal 3.The flushing apparatus illustrated in the drawing consists of a manifold in the form of an elongated block 1 in which two longitudinal channels are formed, namely a liquid supply channel 2 and a suction channel 3.

Væsketilførselskanalen 2 står ved den ene ende i forbindelse med en gennemboring 4, hvori der er anbragt en ventil, der vil blive nærmere beskrevet nedenfor. Den modsatte ende af væsketilførselska 4 147254 nalen 2 er lukket med en skrue 5 med et ydre gevind, der svarer til et indre gevind i kanalen.The fluid supply duct 2 communicates at one end with a piercing 4 in which is arranged a valve which will be described in more detail below. The opposite end of the fluid supply case 4 is closed with a screw 5 with an outer thread corresponding to an internal thread in the channel.

I blokken 1 er der i det viste skylleapparat udformet otte kanaler 6, der strækker sig fra blokken 1's overside gennem kanalen 5 2 og til blokkens underside, og som er udformet vinkelret på kanalen 2.In the block 1, eight channels 6 are formed in the rinsing apparatus which extend from the upper side of the block 1 through the channel 5 2 and to the underside of the block, which are formed perpendicular to the channel 2.

Den del 7 af kanalerne 6, som ligger over kanalen 2, har et indre gevind, og der er heri indskruet skruer 8 med et ydre gevind.The portion 7 of the ducts 6 which overlies the duct 2 has an internal thread, and screws 8 with an external thread are screwed therein.

I den nederste del af kanalerne 6 er der fastgjort væsketilførselsrør 10 9, som strækker sig et stykke ud fra blokken 1.In the lower part of the ducts 6, fluid supply pipes 10 9 are attached which extend a distance from the block 1.

Pi undersiden af blokken 1 er der i heri udformede huller indsat stop klods kerner 10, der i overfladen hver har et ringformet spor, hvori der er indlagt en O-ring 11. De to stop klods kerner 10 er hver omgivet af en udskiftelig afstandsbøsning 12. En kanal 13 for-15 binder gennemboringen 4 med ydersiden af blokken 1, og der er i denne kanal indsat en rørstuds 14.On the underside of block 1, there are inserted stop core cores 10 formed in holes therein, each of which has an annular groove in the surface, in which is inserted an O-ring 11. The two stop globe cores 10 are each surrounded by an interchangeable spacer bush 12 A duct 13 for-15 connects the piercing 4 to the outside of the block 1, and in this duct a pipe nozzle 14 is inserted.

En kanal 15 forbinder den ene ende af sugekanalen 3 med ydersiden af blokken 1, og der er i denne kanal 15 indsat en rørstuds 16. Den modsatte ende af sugekanalen 3 er lukket af en skrue 20 17 med et ydre gevind, der svarer til et indre gevind i kanalen.A duct 15 connects one end of the suction duct 3 with the outside of the block 1, and a duct plug 16 is inserted in this duct 15. The opposite end of the suction duct 3 is closed by a screw 20 17 with an outer thread corresponding to a internal thread in the duct.

I blokken 1 er der desuden udformet otte kanaler, der strækker sig vinkelret ud fra sugekanalen 3, og hvori der er fastgjort sugerør 18, der strækker sig nogle få millimeter længere ud fra blokken 1 end de tilsvarende væsketilførsel s rør 9.In block 1 there are also formed eight channels which extend perpendicularly from the suction channel 3, and in which are attached suction pipes 18 which extend a few millimeters further out from the block 1 than the corresponding liquid supply pipes 9.

25 Ventilen, der er illustreret detaljeret i fig. 4, er som nævnt anbragt i gennemboringen 4 i blokken 1. Ventilen består af et ventillegeme 19, der har en nedre del 20 med en større diameter end den øvre del 21. Mellem den øvre del 21 og den nedre del 20 er et indsnævret område 22. På ydersiden af den øvre del 21 er der udformet 30 et ringformet spor, hvori der er indlagt en O-ring 23. Undersiden af ventillegemet er hul, og der er heri anbragt den øverste del af en spiralfjeder 24, hvis nedre del hviler på en bundprop 25, der er indskruet i den nedre del af gennemboringen 4, og som med en O-ring 26 er tætnet i forhold til blokken 1.The valve illustrated in detail in FIG. 4, as mentioned, is positioned in the bore 4 of block 1. The valve consists of a valve body 19 having a lower portion 20 having a larger diameter than the upper portion 21. Between the upper portion 21 and the lower portion 20 is a narrowed area. 22. On the outside of the upper part 21, an annular groove is formed in which an O-ring 23. is inserted. The underside of the valve body is hollow, and therein is placed the upper part of a coil spring 24, the lower part of which rests. on a bottom plug 25 screwed into the lower portion of the bore 4 and sealed with an O-ring 26 relative to the block 1.

35 Den nedre del af gennemboringen 4 har en større diameter end den øvre del, og den nedre del 20 af ventillegemet 19 forhindres herved i at bevæge sig opad gennem gennemboringen 4. Der er tilvejebragt en tætning mellem blokken 1 og den nedre del 19 af ventillegemet i dette overgangsområde i form af en O-ring 27.The lower part of the bore 4 has a larger diameter than the upper part and the lower part 20 of the valve body 19 is thereby prevented from moving upwards through the bore 4. A seal is provided between the block 1 and the lower part 19 of the valve body. in this transition region in the form of an O-ring 27.

147254 5147254 5

Ved nedtrykning af ventillegemet 19 føres det indsnævrede omride 22 forbi mundingen af kanalen 13; og der etableres herved kontakt mellem væsketilførselsorganerne og væsketilførselskanalen 2, hvorved skyllevæske kan bringes til at strømme ud gennem væsketil-5 førselsrørene 9.By depressing the valve body 19, the constricted area 22 is passed past the mouth of the duct 13; and contact is thereby established between the liquid supply means and the liquid supply channel 2, whereby flushing liquid can be discharged through the liquid supply pipes 9.

Når trykket på ventillegemet 19 ophæves, vil fjederen 24 tvinge den nederste del 20 af legemet 19 opad og dermed afbryde forbindelsen mellem kanalerne 13 og 2.When the pressure on the valve body 19 is lifted, the spring 24 will force the lower part 20 of the body 19 upwards, thus severing the connection between the ducts 13 and 2.

DK503381A 1981-11-13 1981-11-13 MANUALLY USED RINSE RINSE APPLIANCE IN A MICRO TEST PLATE DK147254B (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DK503381A DK147254B (en) 1981-11-13 1981-11-13 MANUALLY USED RINSE RINSE APPLIANCE IN A MICRO TEST PLATE
NO822317A NO151919B (en) 1981-11-13 1982-07-02 APPLIANCE FOR CURRENTLY RINING MULTIPLE ROOMS IN A PLATE
AT82110470T ATE20196T1 (en) 1981-11-13 1982-11-12 HAND OPERATED WASHER FOR MULTI-HOLE PANELS.
CA000415477A CA1181319A (en) 1981-11-13 1982-11-12 Manually operable washer for multi well plates
JP57198787A JPS5892486A (en) 1981-11-13 1982-11-12 Manually operated washer for large number of indented plate
DE8282110470T DE3271585D1 (en) 1981-11-13 1982-11-12 Manually operable washer for multi well plates
EP82110470A EP0080134B1 (en) 1981-11-13 1982-11-12 Manually operable washer for multi well plates

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK503381 1981-11-13
DK503381A DK147254B (en) 1981-11-13 1981-11-13 MANUALLY USED RINSE RINSE APPLIANCE IN A MICRO TEST PLATE

Publications (2)

Publication Number Publication Date
DK503381A DK503381A (en) 1983-05-14
DK147254B true DK147254B (en) 1984-05-28

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EP (1) EP0080134B1 (en)
JP (1) JPS5892486A (en)
AT (1) ATE20196T1 (en)
CA (1) CA1181319A (en)
DE (1) DE3271585D1 (en)
DK (1) DK147254B (en)
NO (1) NO151919B (en)

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BE856748A (en) * 1976-07-16 1977-10-31 Dynatech Worldmed METHOD AND DEVICE FOR CLEANING MICRO-TEST PLATES
DE3028746C2 (en) * 1980-07-29 1985-11-28 Guido 7919 Bellenberg Oberdorfer High pressure cleaning system
DE3029440C2 (en) * 1980-08-02 1983-01-13 Ernst 4030 Ratingen Fooke Device for washing solids

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Publication number Publication date
DK503381A (en) 1983-05-14
NO151919B (en) 1985-03-25
ATE20196T1 (en) 1986-06-15
CA1181319A (en) 1985-01-22
DE3271585D1 (en) 1986-07-10
JPS5892486A (en) 1983-06-01
EP0080134B1 (en) 1986-06-04
NO822317L (en) 1983-05-16
EP0080134A1 (en) 1983-06-01

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