DK1421938T3 - Antitumormidler og fremgangsmåde til at producere samme - Google Patents
Antitumormidler og fremgangsmåde til at producere sammeInfo
- Publication number
- DK1421938T3 DK1421938T3 DK02758880.5T DK02758880T DK1421938T3 DK 1421938 T3 DK1421938 T3 DK 1421938T3 DK 02758880 T DK02758880 T DK 02758880T DK 1421938 T3 DK1421938 T3 DK 1421938T3
- Authority
- DK
- Denmark
- Prior art keywords
- conjugated
- producing
- methods
- same
- tumor agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001264918A JP5000050B2 (ja) | 2001-08-31 | 2001-08-31 | 抗腫瘍剤及びその製造方法 |
| PCT/JP2002/008707 WO2003018007A1 (fr) | 2001-08-31 | 2002-08-29 | Agents anticancereux et leur procede de production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1421938T3 true DK1421938T3 (da) | 2010-05-17 |
Family
ID=19091449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02758880.5T DK1421938T3 (da) | 2001-08-31 | 2002-08-29 | Antitumormidler og fremgangsmåde til at producere samme |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7026488B2 (da) |
| EP (1) | EP1421938B1 (da) |
| JP (1) | JP5000050B2 (da) |
| KR (1) | KR100876343B1 (da) |
| CN (1) | CN100406010C (da) |
| AT (1) | ATE456951T1 (da) |
| CA (1) | CA2458744C (da) |
| DE (1) | DE60235279D1 (da) |
| DK (1) | DK1421938T3 (da) |
| ES (1) | ES2339430T3 (da) |
| WO (1) | WO2003018007A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004196770A (ja) * | 2002-10-24 | 2004-07-15 | Effector Cell Institute Inc | 樹状細胞前駆体の血中レベル上昇剤 |
| GB2397067B (en) | 2002-12-23 | 2005-05-11 | Destiny Pharma Ltd | Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation |
| GB2408265A (en) * | 2003-11-21 | 2005-05-25 | Univ Sheffield | Water-soluble hyperbranched polymer porphyrins |
| GB2415372A (en) | 2004-06-23 | 2005-12-28 | Destiny Pharma Ltd | Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent |
| CA2605205C (en) | 2005-04-18 | 2011-11-01 | Hiroshi Maeda | Polymeric pharmaceutical agent for treatment of cancer and method for production of the same |
| WO2008014266A2 (en) * | 2006-07-24 | 2008-01-31 | University Of Maryland, Baltimore | Heme oxygenase inhibitors and methods of therapeutic use |
| US20100255050A1 (en) * | 2007-07-24 | 2010-10-07 | James Klein Leonard | Polyethylene Based Bioactive Agents |
| JP2010024170A (ja) * | 2008-07-17 | 2010-02-04 | Hiroshi Maeda | 抗悪性腫瘍剤の腫瘍組織への局所送達増強剤 |
| CN102000070B (zh) * | 2009-07-08 | 2012-05-23 | 山东弘立医学动物实验研究有限公司 | 用于治疗肿瘤的锰卟啉-氯尼达明联合用药物 |
| KR101164138B1 (ko) | 2009-12-24 | 2012-07-11 | 재단법인대구경북과학기술원 | 광역학 치료용 수용성 나노구조체 |
| CN101948566B (zh) * | 2010-06-23 | 2012-09-19 | 中国科学院化学研究所 | 一种用于抗真菌、抗癌及细胞成像的多功能聚合物及其制备方法 |
| EP2774625B1 (en) * | 2011-09-05 | 2017-04-12 | Hiroshi Maeda | Polymer-type fluorescent molecule probe |
| CN104069492B (zh) * | 2014-01-24 | 2019-05-28 | 中国科学院福建物质结构研究所 | 靶向表达尿激酶受体的肿瘤的光敏剂及其制备方法和用途 |
| CN108610346B (zh) * | 2018-04-02 | 2020-06-02 | 杭州至重医药科技有限公司 | 一种光敏酞菁固体材料及其制备方法与应用 |
| CN114262442B (zh) * | 2021-12-24 | 2023-05-02 | 厦门金达威生物科技有限公司 | 一种两亲聚合物和脂溶性营养素纳米颗粒及其制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2645079A1 (de) * | 1976-10-06 | 1978-04-13 | Bayer Ernst | Polymere sauerstofftraeger und verfahren zu ihrer herstellung |
| JPS584061B2 (ja) * | 1979-04-27 | 1983-01-24 | 森六株式会社 | ブロック共重合体金属錯体 |
| US5403928A (en) * | 1990-05-15 | 1995-04-04 | Diatron Corporation | Fluorescent marker components and fluorescent probes |
| US5622685A (en) * | 1990-05-30 | 1997-04-22 | Deutches Krebsforchunszentrum Stiftung Des Offentlichen Rechts | Polyether-substituted porphyrin anti-tumor agents |
| DE69214328T2 (de) | 1991-03-05 | 1997-02-20 | Hitachi Chemical Co Ltd | Wasserlösliche Tetrazaporphin und Fluoreszenzmarkierungsstoff |
| US6362175B1 (en) * | 1991-09-20 | 2002-03-26 | The Trustees Of The University Of Pennsylvania | Porphyrin compounds for imaging tissue oxygen |
| DE69129150T2 (de) * | 1991-10-14 | 1998-10-08 | Procter & Gamble | Waschmittelzusammensetzungen mit Zusätzen zur Verhinderung der Farbstoffübertragung |
| DE4232925A1 (de) * | 1992-09-28 | 1994-03-31 | Diagnostikforschung Inst | 3-,8-substituierte Deuteroporphyrinderivate, diese enthaltende pharmazeutische Mittel und Verfahren zu ihrer Herstellung |
| GB9408746D0 (en) * | 1994-05-03 | 1994-06-22 | Scotia Holdings Plc | Tumour locallising photosensitising compounds |
| US5756726A (en) * | 1995-06-02 | 1998-05-26 | Pharmacyclics, Inc. | Methods of producing singlet oxygen using compounds having improved functionalization |
| US20020155999A1 (en) * | 1998-04-30 | 2002-10-24 | Han In Suk | Method of using a porphyrin-like molecule conjugated with an anti-cancer drug for the treatment of cancer |
| GB0001455D0 (en) * | 2000-01-21 | 2000-03-15 | Scotia Holdings Plc | Porphyrins and related compounds |
-
2001
- 2001-08-31 JP JP2001264918A patent/JP5000050B2/ja not_active Expired - Fee Related
-
2002
- 2002-08-29 DK DK02758880.5T patent/DK1421938T3/da active
- 2002-08-29 WO PCT/JP2002/008707 patent/WO2003018007A1/ja active Application Filing
- 2002-08-29 DE DE60235279T patent/DE60235279D1/de not_active Expired - Lifetime
- 2002-08-29 CA CA2458744A patent/CA2458744C/en not_active Expired - Fee Related
- 2002-08-29 EP EP02758880A patent/EP1421938B1/en not_active Expired - Lifetime
- 2002-08-29 ES ES02758880T patent/ES2339430T3/es not_active Expired - Lifetime
- 2002-08-29 US US10/484,726 patent/US7026488B2/en not_active Expired - Lifetime
- 2002-08-29 CN CNB028171373A patent/CN100406010C/zh not_active Expired - Fee Related
- 2002-08-29 AT AT02758880T patent/ATE456951T1/de active
- 2002-08-29 KR KR1020047001975A patent/KR100876343B1/ko active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN100406010C (zh) | 2008-07-30 |
| DE60235279D1 (de) | 2010-03-25 |
| ES2339430T3 (es) | 2010-05-20 |
| CA2458744C (en) | 2010-09-14 |
| CN1549712A (zh) | 2004-11-24 |
| JP2003073273A (ja) | 2003-03-12 |
| EP1421938A1 (en) | 2004-05-26 |
| US20040234495A1 (en) | 2004-11-25 |
| JP5000050B2 (ja) | 2012-08-15 |
| KR100876343B1 (ko) | 2008-12-29 |
| CA2458744A1 (en) | 2003-03-06 |
| US7026488B2 (en) | 2006-04-11 |
| WO2003018007A1 (fr) | 2003-03-06 |
| EP1421938A4 (en) | 2005-11-23 |
| ATE456951T1 (de) | 2010-02-15 |
| KR20040030951A (ko) | 2004-04-09 |
| EP1421938B1 (en) | 2010-02-03 |
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