DK1409538T3 - Fremgangsmåde til opnåelse af vækstfaktor- (TGF-beta og IGF-1), lactoperoxidase- og immunoglobulinpræparater fra mælkeprodukter med lav indbyrdes krydskontaminering - Google Patents
Fremgangsmåde til opnåelse af vækstfaktor- (TGF-beta og IGF-1), lactoperoxidase- og immunoglobulinpræparater fra mælkeprodukter med lav indbyrdes krydskontamineringInfo
- Publication number
- DK1409538T3 DK1409538T3 DK02747753T DK02747753T DK1409538T3 DK 1409538 T3 DK1409538 T3 DK 1409538T3 DK 02747753 T DK02747753 T DK 02747753T DK 02747753 T DK02747753 T DK 02747753T DK 1409538 T3 DK1409538 T3 DK 1409538T3
- Authority
- DK
- Denmark
- Prior art keywords
- igf
- tgf
- beta
- lactoperoxidase
- growth factor
- Prior art date
Links
- 239000003102 growth factor Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 title abstract 2
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 title abstract 2
- 239000008267 milk Substances 0.000 title abstract 2
- 210000004080 milk Anatomy 0.000 title abstract 2
- 235000013336 milk Nutrition 0.000 title abstract 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 title 1
- 108010023244 Lactoperoxidase Proteins 0.000 title 1
- 102000045576 Lactoperoxidases Human genes 0.000 title 1
- 102000004887 Transforming Growth Factor beta Human genes 0.000 title 1
- 108090001012 Transforming Growth Factor beta Proteins 0.000 title 1
- 238000012864 cross contamination Methods 0.000 title 1
- 102000018358 immunoglobulin Human genes 0.000 title 1
- 229940057428 lactoperoxidase Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000011347 resin Substances 0.000 abstract 3
- 229920005989 resin Polymers 0.000 abstract 3
- 239000003446 ligand Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 238000004191 hydrophobic interaction chromatography Methods 0.000 abstract 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202794 | 2001-07-20 | ||
| EP01202795 | 2001-07-20 | ||
| PCT/NL2002/000496 WO2003008447A1 (fr) | 2001-07-20 | 2002-07-22 | Procede d'obtention de facteur de croissance (tgf-beta et igf-1), lactoperoxydase et compositions d'immunoglobulines a partir de produits laitiers dotes de contamination croisee mutuelle basse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1409538T3 true DK1409538T3 (da) | 2009-04-14 |
Family
ID=26076963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02747753T DK1409538T3 (da) | 2001-07-20 | 2002-07-22 | Fremgangsmåde til opnåelse af vækstfaktor- (TGF-beta og IGF-1), lactoperoxidase- og immunoglobulinpræparater fra mælkeprodukter med lav indbyrdes krydskontaminering |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040219225A1 (fr) |
| EP (1) | EP1409538B1 (fr) |
| CN (1) | CN1555384B (fr) |
| AT (1) | ATE420108T1 (fr) |
| AU (1) | AU2002318066B2 (fr) |
| CA (1) | CA2454548A1 (fr) |
| DE (1) | DE60230763D1 (fr) |
| DK (1) | DK1409538T3 (fr) |
| NZ (1) | NZ530704A (fr) |
| WO (1) | WO2003008447A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2827290B1 (fr) | 2001-07-13 | 2004-07-09 | Pierre Jouan Biotechnologies Sa | Procede d'obtention d'une fraction proteique enrichie en tgf-beta sous forme activee, fraction proteique et applications therapeutiques |
| FR2889068B1 (fr) * | 2005-07-29 | 2012-03-02 | Cie Laitiere Europeenne | Nouvelles fractions proteiques laitieres et leur utilisation pour la prevention ou le traitement des maladies inflammatoires chroniques |
| FR2901707B1 (fr) | 2006-05-31 | 2017-09-29 | Lab Francais Du Fractionnement | Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis |
| FR2910786B1 (fr) | 2006-12-29 | 2017-08-11 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies (Lfb) | "procede d'extraction d'une proteine presente dans du lait" |
| FR2912310B1 (fr) | 2007-02-13 | 2009-08-07 | Kasan Sarl | Nouvelles compositions cosmetiques et/ou pharmaceutiques et leurs applications. |
| ATE542541T1 (de) * | 2007-04-03 | 2012-02-15 | Advitech Inc | Verfahren zur herstellung einer entzündungshemmenden zusammensetzung auf milchbasis |
| EP2244735A4 (fr) | 2007-10-02 | 2011-02-23 | Avaxia Biologics Inc | Thérapie aux anticorps pour une utilisation dans le tube digestif |
| US8367354B2 (en) * | 2008-10-24 | 2013-02-05 | Mead Johnson Nutrition Company | Methods for determining the levels of TGF-β in a composition |
| US8861162B2 (en) * | 2010-03-09 | 2014-10-14 | Honeywell International Inc. | High power solid state power controller (SSPC) solution for primary power distribution applications |
| WO2012141791A1 (fr) * | 2011-02-22 | 2012-10-18 | Avaxia Biologics, Inc. | Compositions d'anticorps polyclonaux |
| AU2013204858B2 (en) * | 2012-10-08 | 2015-06-25 | Saputo Dairy Australia Pty Limited | Improved process for purifying milk proteins and products thereof |
| AU2013204850B2 (en) * | 2012-10-08 | 2015-06-25 | Murray Goulburn Co-Operative Co. Limited | Improved process for purifying milk proteins and products thereof |
| CN108676784B (zh) * | 2018-06-06 | 2021-04-27 | 中国农业科学院北京畜牧兽医研究所 | 一种牛乳中乳过氧化物酶的纯化方法 |
| US11109604B2 (en) | 2019-05-09 | 2021-09-07 | Memtec LLC | Dairy processing systems and methods |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8806893D0 (en) * | 1988-03-23 | 1988-04-27 | Unilever Plc | Cosmetic composition |
| NL1005677C2 (nl) * | 1997-03-27 | 1998-09-29 | Campina Melkunie Bv | Werkwijze voor het winnen van groeifactoren, of een samenstelling die één of meer groeifactoren bevat, uit melk of een derivaat daarvan. |
| GB9708641D0 (en) * | 1997-04-29 | 1997-06-18 | Knoll Ag | Enzyme concentrate |
| EP1218410B1 (fr) * | 1999-10-06 | 2005-06-15 | Campina B.V. | Procede pour obtenir des preparations de facteurs de croissance (tgf-beta et igf-1) a partir de produits laitiers avec une faible contamination mutuelle croisee |
-
2002
- 2002-07-22 AT AT02747753T patent/ATE420108T1/de not_active IP Right Cessation
- 2002-07-22 CA CA002454548A patent/CA2454548A1/fr not_active Abandoned
- 2002-07-22 US US10/484,255 patent/US20040219225A1/en not_active Abandoned
- 2002-07-22 EP EP02747753A patent/EP1409538B1/fr not_active Expired - Lifetime
- 2002-07-22 DE DE60230763T patent/DE60230763D1/de not_active Expired - Fee Related
- 2002-07-22 WO PCT/NL2002/000496 patent/WO2003008447A1/fr not_active Application Discontinuation
- 2002-07-22 AU AU2002318066A patent/AU2002318066B2/en not_active Ceased
- 2002-07-22 CN CN028182111A patent/CN1555384B/zh not_active Expired - Fee Related
- 2002-07-22 DK DK02747753T patent/DK1409538T3/da active
- 2002-07-22 NZ NZ530704A patent/NZ530704A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1409538A1 (fr) | 2004-04-21 |
| DE60230763D1 (de) | 2009-02-26 |
| WO2003008447A8 (fr) | 2003-03-20 |
| EP1409538B1 (fr) | 2009-01-07 |
| US20040219225A1 (en) | 2004-11-04 |
| WO2003008447A1 (fr) | 2003-01-30 |
| NZ530704A (en) | 2005-07-29 |
| CN1555384B (zh) | 2010-05-26 |
| CA2454548A1 (fr) | 2003-01-30 |
| ATE420108T1 (de) | 2009-01-15 |
| CN1555384A (zh) | 2004-12-15 |
| AU2002318066B2 (en) | 2007-10-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1409538T3 (da) | Fremgangsmåde til opnåelse af vækstfaktor- (TGF-beta og IGF-1), lactoperoxidase- og immunoglobulinpræparater fra mælkeprodukter med lav indbyrdes krydskontaminering | |
| DK0804070T3 (da) | Fremgangsmåde til isolering af proteiner fra mælk | |
| PL374311A1 (en) | Methods for purifying protein | |
| UA48105C2 (uk) | ФРАГМЕНТ ДНК, ЯКИЙ КОДУЄ БІЛОК РОДИНИ TGF-<font face="Symbol">b</font> (ВАРІАНТИ), РЕКОМБІНАНТНА МОЛЕКУЛА ДНК (ВАРІАНТИ), КЛІТИНА-ХАЗЯЇН (ВАРІАНТИ), СПОСІБ ОДЕРЖАННЯ БІЛКУ РОДИНИ TGF-<font face="Symbol">b</font> (ВАРІАНТИ), БІЛОК РОДИНИ TGF-<font face="Symbol">b</font> (ВАРІАНТИ), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ (ВАРІАНТИ), АНТИТІЛО АБО ФРАГМЕНТ АНТИТІЛА (ВАРІАНТИ), МОЛЕКУЛА КДНК (ВАРІАНТИ) | |
| DK1427758T3 (da) | Præparater og fremgangsmåder til behandling af diabetes | |
| WO2006016960A3 (fr) | Procédé servant à purifier une protéine de la superfamille des protéines à noeud cystine | |
| NO20012700L (no) | Sett uten kaotrope bestanddeler for isolering av nukleinsyrer, fortrinnsvis DNA, fra eventuelt komplekse utgangsmaterialer ved binding til en fast fase, fremgangsmater for isolering av nukleinsyrene, samt anvendelse av antikaotrope bestanddeler for isolering og rensing av nukleinsyrer. | |
| WO2006031560A3 (fr) | Procede pour concentrer des anticorps, et produits therapeutiques correspondants | |
| WO2005103083A3 (fr) | Anticorps humains anti-cd38 et utilisations de ceux-ci | |
| CA2381219A1 (fr) | Proteine monomere de la famille des tgf-beta | |
| DK677688A (da) | Humane somatomedinbaererproteinunderenheder og fremgangsmaade til fremstilling af saadanne | |
| DE69433690D1 (de) | Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür | |
| DE69926226D1 (de) | Neues verfahren zur trennung von proteinen unter verwendung eines ca++ enthaltenden elutionsmittels | |
| DK1218410T3 (da) | Fremgangsmåde til opnåelse af vækstfaktorpræparater (TGF-beta og IGF-1) med lav gensidig krydskontamination ud fra mælkeprodukter | |
| ATE395360T1 (de) | Neues verfahren zur aufreinigung von humanem wachstumshormon | |
| Singh | Determination of uncombined intermediates in FD&C yellow No. 6 by high-pressure liquid chromatography | |
| ATE528393T1 (de) | Verfahren zur reinigung von protein und glucosedehydrogenase | |
| PT659883E (pt) | Proteina p140 e adn que a codifica | |
| Sarer et al. | Composition of the essential oil from Nepeta nuda ssp. albiflora (Boiss.) Gams | |
| WO2003028666A3 (fr) | Polypeptides isoles et compositions obtenues a partir du venin de p. transvaalicus et leurs procedes d'utilisation | |
| AU2001278684A1 (en) | Protein induced by homogeneous blood transfusion and dna encoding the same | |
| MIYAUCHI | Studies on Erythrocyte Hemins. I. Separation of Erythrocyte Hemins by Thin-layer Chromatography | |
| AU7525091A (en) | Growth hormone releasing factor analogs | |
| DE59207362D1 (de) | Monoklonale Antikörper gegen den Plasmin-Antiplasmin Komplex, Verfahren zu ihrer Herstellung sowie ihre Verwendung | |
| CA3156649A1 (fr) | Purification de proteines et inactivation virale |