DK1409036T3 - Protesekomponenter med oxiderede zirconiumoverflader i kontakt med overflader af tværbundet polyethylen - Google Patents
Protesekomponenter med oxiderede zirconiumoverflader i kontakt med overflader af tværbundet polyethylenInfo
- Publication number
- DK1409036T3 DK1409036T3 DK02747028T DK02747028T DK1409036T3 DK 1409036 T3 DK1409036 T3 DK 1409036T3 DK 02747028 T DK02747028 T DK 02747028T DK 02747028 T DK02747028 T DK 02747028T DK 1409036 T3 DK1409036 T3 DK 1409036T3
- Authority
- DK
- Denmark
- Prior art keywords
- cross
- linked polyethylene
- zirconium
- contact
- oxidized zirconium
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
- A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/04—Homopolymers or copolymers of ethene
- C08L23/06—Polyethene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2312/00—Crosslinking
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2312/00—Crosslinking
- C08L2312/06—Crosslinking by radiation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Dental Prosthetics (AREA)
- Surgical Instruments (AREA)
- Pens And Brushes (AREA)
- Dental Preparations (AREA)
- Other Surface Treatments For Metallic Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/908,520 US6652586B2 (en) | 2001-07-18 | 2001-07-18 | Prosthetic devices employing oxidized zirconium and other abrasion resistant surfaces contacting surfaces of cross-linked polyethylene |
PCT/US2002/022488 WO2003008008A1 (en) | 2001-07-18 | 2002-07-16 | Prosthetic devices employing oxidized zirconium surfaces contacting surfaces of cross-linked polyethylene |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1409036T3 true DK1409036T3 (da) | 2008-09-22 |
Family
ID=25425922
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02747028T DK1409036T3 (da) | 2001-07-18 | 2002-07-16 | Protesekomponenter med oxiderede zirconiumoverflader i kontakt med overflader af tværbundet polyethylen |
Country Status (13)
Country | Link |
---|---|
US (1) | US6652586B2 (da) |
EP (1) | EP1409036B1 (da) |
JP (2) | JP2005506858A (da) |
KR (1) | KR100920275B1 (da) |
CN (1) | CN1253215C (da) |
AT (1) | ATE395093T1 (da) |
AU (1) | AU2002316702B2 (da) |
CA (1) | CA2454349A1 (da) |
DE (1) | DE60226607D1 (da) |
DK (1) | DK1409036T3 (da) |
ES (1) | ES2302824T3 (da) |
PT (1) | PT1409036E (da) |
WO (1) | WO2003008008A1 (da) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6585772B2 (en) * | 1997-03-27 | 2003-07-01 | Smith & Nephew, Inc. | Method of surface oxidizing zirconium and zirconium alloys and resulting product |
AU736216B2 (en) * | 1997-03-27 | 2001-07-26 | Smith & Nephew, Inc. | Method of surface oxidizing zirconium alloys and resulting product |
FR2807315B1 (fr) * | 2000-04-06 | 2003-01-17 | Rech S Et De Fabrication S E R | Insert cotyloidien pour prothese totale de la hanche |
US8123814B2 (en) | 2001-02-23 | 2012-02-28 | Biomet Manufacturing Corp. | Method and appartus for acetabular reconstruction |
US7597715B2 (en) | 2005-04-21 | 2009-10-06 | Biomet Manufacturing Corp. | Method and apparatus for use of porous implants |
FR2824261B1 (fr) | 2001-05-04 | 2004-05-28 | Ldr Medical | Prothese de disque intervertebral et procede et outils de mise en place |
US7182784B2 (en) * | 2001-07-18 | 2007-02-27 | Smith & Nephew, Inc. | Prosthetic devices employing oxidized zirconium and other abrasion resistant surfaces contacting surfaces of cross-linked polyethylene |
US20030153979A1 (en) * | 2002-02-11 | 2003-08-14 | Dean Hughes | Posterior stabilized knee system prosthetic devices employing diffusion-hardened surfaces |
FR2846550B1 (fr) | 2002-11-05 | 2006-01-13 | Ldr Medical | Prothese de disque intervertebral |
US20040122524A1 (en) * | 2002-12-18 | 2004-06-24 | Smith & Nephew, Inc. | Bi-polar hip prosthetic devices employing diffusion-hardened surfaces |
US7708782B2 (en) | 2003-07-17 | 2010-05-04 | Exactech, Inc. | Mobile bearing knee prosthesis |
AU2004258934B2 (en) * | 2003-07-17 | 2010-06-03 | Exactech, Inc. | Mobile bearing knee prosthesis |
EP1648348B1 (en) | 2003-07-24 | 2015-06-17 | Tecomet Inc. | Assembled non-random foams |
US6974625B2 (en) * | 2003-12-16 | 2005-12-13 | Smith & Nephew, Inc. | Oxidized zirconium on a porous structure for bone implant use |
FR2865629B1 (fr) | 2004-02-04 | 2007-01-26 | Ldr Medical | Prothese de disque intervertebral |
EP2113227B1 (en) | 2004-02-04 | 2015-07-29 | LDR Medical | Intervertebral disc prosthesis |
US20050197713A1 (en) * | 2004-03-01 | 2005-09-08 | Catlin Mark G. | Ternary single-phase ceramic medical devices |
US7338529B1 (en) | 2004-03-30 | 2008-03-04 | Biomet Manufacturing Corp. | Methods and apparatuses for enhancing prosthetic implant durability |
FR2869528B1 (fr) | 2004-04-28 | 2007-02-02 | Ldr Medical | Prothese de disque intervertebral |
US20060009857A1 (en) * | 2004-07-08 | 2006-01-12 | Gibbs Phillip M | Method and apparatus for surface hardening implants |
US7473278B2 (en) | 2004-09-16 | 2009-01-06 | Smith & Nephew, Inc. | Method of surface oxidizing zirconium and zirconium alloys and resulting product |
US8021392B2 (en) | 2004-11-22 | 2011-09-20 | Minsurg International, Inc. | Methods and surgical kits for minimally-invasive facet joint fusion |
US20060111779A1 (en) * | 2004-11-22 | 2006-05-25 | Orthopedic Development Corporation, A Florida Corporation | Minimally invasive facet joint fusion |
US8172855B2 (en) | 2004-11-24 | 2012-05-08 | Abdou M S | Devices and methods for inter-vertebral orthopedic device placement |
US20060122694A1 (en) * | 2004-12-03 | 2006-06-08 | Stinson Jonathan S | Medical devices and methods of making the same |
FR2879436B1 (fr) | 2004-12-22 | 2007-03-09 | Ldr Medical | Prothese de disque intervertebral |
US8266780B2 (en) | 2005-04-21 | 2012-09-18 | Biomet Manufacturing Corp. | Method and apparatus for use of porous implants |
US8066778B2 (en) | 2005-04-21 | 2011-11-29 | Biomet Manufacturing Corp. | Porous metal cup with cobalt bearing surface |
US8292967B2 (en) | 2005-04-21 | 2012-10-23 | Biomet Manufacturing Corp. | Method and apparatus for use of porous implants |
US8021432B2 (en) | 2005-12-05 | 2011-09-20 | Biomet Manufacturing Corp. | Apparatus for use of porous implants |
US8071155B2 (en) * | 2005-05-05 | 2011-12-06 | Boston Scientific Scimed, Inc. | Medical devices and methods of making the same |
FR2887762B1 (fr) | 2005-06-29 | 2007-10-12 | Ldr Medical Soc Par Actions Si | Instrumentation d'insertion de prothese de disque intervertebral entre des vertebres |
FR2891135B1 (fr) | 2005-09-23 | 2008-09-12 | Ldr Medical Sarl | Prothese de disque intervertebral |
US8034113B2 (en) | 2005-09-27 | 2011-10-11 | Randall Lane Acker | Joint prosthesis and method of implanting same |
US8012214B2 (en) | 2005-09-27 | 2011-09-06 | Randall Lane Acker | Joint prosthesis |
FR2893838B1 (fr) | 2005-11-30 | 2008-08-08 | Ldr Medical Soc Par Actions Si | Prothese de disque intervertebral et instrumentation d'insertion de la prothese entre les vertebres |
WO2007078427A2 (en) * | 2005-12-15 | 2007-07-12 | Smith & Nephew, Inc. | Diffusion-hardened medical implant |
US8070821B2 (en) * | 2005-12-27 | 2011-12-06 | Howmedica Osteonics Corp. | Hybrid femoral implant |
US8562616B2 (en) | 2007-10-10 | 2013-10-22 | Biomet Manufacturing, Llc | Knee joint prosthesis system and method for implantation |
US8163028B2 (en) | 2007-01-10 | 2012-04-24 | Biomet Manufacturing Corp. | Knee joint prosthesis system and method for implantation |
US8328873B2 (en) | 2007-01-10 | 2012-12-11 | Biomet Manufacturing Corp. | Knee joint prosthesis system and method for implantation |
EP2104474B1 (en) | 2007-01-10 | 2012-08-29 | Biomet Manufacturing Corp. | Knee joint prosthesis system |
US8187280B2 (en) | 2007-10-10 | 2012-05-29 | Biomet Manufacturing Corp. | Knee joint prosthesis system and method for implantation |
US8465546B2 (en) | 2007-02-16 | 2013-06-18 | Ldr Medical | Intervertebral disc prosthesis insertion assemblies |
US7833274B2 (en) * | 2007-05-16 | 2010-11-16 | Zimmer, Inc. | Knee system and method of making same |
FR2916956B1 (fr) | 2007-06-08 | 2012-12-14 | Ldr Medical | Cage intersomatique,prothese intervertebrale,dispositif d'ancrage et instrumentation d'implantation |
WO2009029207A1 (en) * | 2007-08-27 | 2009-03-05 | Vladimir Shur | Knee prosthesis |
DE102008047009B4 (de) * | 2008-07-11 | 2020-08-06 | Mathys Ag Bettlach | Gelenkpfanne mit physiologischer Lastübertragung |
US8361381B2 (en) | 2008-09-25 | 2013-01-29 | Smith & Nephew, Inc. | Medical implants having a porous coated surface |
US8123815B2 (en) | 2008-11-24 | 2012-02-28 | Biomet Manufacturing Corp. | Multiple bearing acetabular prosthesis |
US8308810B2 (en) | 2009-07-14 | 2012-11-13 | Biomet Manufacturing Corp. | Multiple bearing acetabular prosthesis |
US8764806B2 (en) | 2009-12-07 | 2014-07-01 | Samy Abdou | Devices and methods for minimally invasive spinal stabilization and instrumentation |
GB0922339D0 (en) | 2009-12-21 | 2010-02-03 | Mcminn Derek J W | Acetabular cup prothesis and introducer thereof |
EP2555712B1 (en) * | 2010-04-09 | 2018-02-21 | Excera Orthopedics, Inc. | Hip implant |
US8142511B2 (en) | 2010-04-19 | 2012-03-27 | Zimmer, Inc. | Bi-material prosthesis component |
WO2012021764A2 (en) * | 2010-08-13 | 2012-02-16 | Smith & Nephew, Inc. | Orthopaedic implants and methods |
CN105769315A (zh) * | 2010-10-21 | 2016-07-20 | 思必瑞特脊椎股份有限公司 | 人工髋关节置换系统 |
KR101649746B1 (ko) * | 2011-01-21 | 2016-08-23 | 한국과학기술연구원 | 인공 관절용 소재의 제조 방법 |
US8845728B1 (en) | 2011-09-23 | 2014-09-30 | Samy Abdou | Spinal fixation devices and methods of use |
US20130226240A1 (en) | 2012-02-22 | 2013-08-29 | Samy Abdou | Spinous process fixation devices and methods of use |
US9198767B2 (en) | 2012-08-28 | 2015-12-01 | Samy Abdou | Devices and methods for spinal stabilization and instrumentation |
US9320617B2 (en) | 2012-10-22 | 2016-04-26 | Cogent Spine, LLC | Devices and methods for spinal stabilization and instrumentation |
US9949837B2 (en) | 2013-03-07 | 2018-04-24 | Howmedica Osteonics Corp. | Partially porous bone implant keel |
CN104921845A (zh) * | 2015-07-03 | 2015-09-23 | 江苏奥康尼医疗科技发展有限公司 | 一种骨缺损填充物 |
US10857003B1 (en) | 2015-10-14 | 2020-12-08 | Samy Abdou | Devices and methods for vertebral stabilization |
EP3435925B1 (en) * | 2016-03-29 | 2024-05-01 | Facet Dynamics, Inc. | Facet joint replacement device |
US10973648B1 (en) | 2016-10-25 | 2021-04-13 | Samy Abdou | Devices and methods for vertebral bone realignment |
US10744000B1 (en) | 2016-10-25 | 2020-08-18 | Samy Abdou | Devices and methods for vertebral bone realignment |
WO2019171158A1 (es) * | 2018-03-09 | 2019-09-12 | Perez Nunez Rafael Eduardo | Prótesis para reemplazo de cadera con cabeza de polietileno altamente entrecruzado |
CN108670503A (zh) * | 2018-07-25 | 2018-10-19 | 南京医科大学附属逸夫医院 | 一种含有钛镍记忆合金倒刺的生物型股骨柄及其使用方法 |
US11179248B2 (en) | 2018-10-02 | 2021-11-23 | Samy Abdou | Devices and methods for spinal implantation |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5152794A (en) | 1989-07-25 | 1992-10-06 | Smith & Nephew Richards Inc. | Zirconium oxide and nitride coated prothesis for reduced microfretting |
US5370694A (en) | 1989-07-25 | 1994-12-06 | Smith & Nephew Richards, Inc. | Zirconium oxide and nitride coated endoprostheses for tissue protection |
US5037438A (en) | 1989-07-25 | 1991-08-06 | Richards Medical Company | Zirconium oxide coated prosthesis for wear and corrosion resistance |
CA2021814C (en) | 1989-07-25 | 2002-04-02 | James A. Davidson | Zirconium alloy-based prosthesis with zirconium oxide or zirconium nitride coating |
US5414049A (en) * | 1993-06-01 | 1995-05-09 | Howmedica Inc. | Non-oxidizing polymeric medical implant |
CA2654851C (en) * | 1994-09-21 | 2011-01-18 | Bmg Incorporated | Ultra high molecular weight polyethylene molded article for artificial joints and method of preparing the same |
CA2166450C (en) * | 1995-01-20 | 2008-03-25 | Ronald Salovey | Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints |
US5577368A (en) * | 1995-04-03 | 1996-11-26 | Johnson & Johnson Professional, Inc. | Method for improving wear resistance of polymeric bioimplantable components |
US5879400A (en) * | 1996-02-13 | 1999-03-09 | Massachusetts Institute Of Technology | Melt-irradiated ultra high molecular weight polyethylene prosthetic devices |
EP2319546A1 (en) * | 1996-07-09 | 2011-05-11 | Orthopaedic Hospital | Crosslinking of polytheylene for low wear using radiation and thermal treatments |
US6228900B1 (en) * | 1996-07-09 | 2001-05-08 | The Orthopaedic Hospital And University Of Southern California | Crosslinking of polyethylene for low wear using radiation and thermal treatments |
US6017975A (en) * | 1996-10-02 | 2000-01-25 | Saum; Kenneth Ashley | Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance |
EP1028760B1 (en) * | 1996-10-15 | 2004-04-14 | Orthopaedic Hospital | Wear resistant surface-gradient cross-linked polyethylene |
AU736216B2 (en) * | 1997-03-27 | 2001-07-26 | Smith & Nephew, Inc. | Method of surface oxidizing zirconium alloys and resulting product |
-
2001
- 2001-07-18 US US09/908,520 patent/US6652586B2/en not_active Expired - Lifetime
-
2002
- 2002-07-16 AT AT02747028T patent/ATE395093T1/de active
- 2002-07-16 JP JP2003513612A patent/JP2005506858A/ja active Pending
- 2002-07-16 ES ES02747028T patent/ES2302824T3/es not_active Expired - Lifetime
- 2002-07-16 DK DK02747028T patent/DK1409036T3/da active
- 2002-07-16 DE DE60226607T patent/DE60226607D1/de not_active Expired - Lifetime
- 2002-07-16 WO PCT/US2002/022488 patent/WO2003008008A1/en active Application Filing
- 2002-07-16 AU AU2002316702A patent/AU2002316702B2/en not_active Expired
- 2002-07-16 CN CNB028182510A patent/CN1253215C/zh not_active Expired - Lifetime
- 2002-07-16 CA CA002454349A patent/CA2454349A1/en not_active Abandoned
- 2002-07-16 KR KR1020047000784A patent/KR100920275B1/ko active IP Right Grant
- 2002-07-16 EP EP02747028A patent/EP1409036B1/en not_active Expired - Lifetime
- 2002-07-16 PT PT02747028T patent/PT1409036E/pt unknown
-
2009
- 2009-04-22 JP JP2009104304A patent/JP5249120B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2005506858A (ja) | 2005-03-10 |
CN1555275A (zh) | 2004-12-15 |
ES2302824T3 (es) | 2008-08-01 |
KR20040017324A (ko) | 2004-02-26 |
JP5249120B2 (ja) | 2013-07-31 |
JP2009195723A (ja) | 2009-09-03 |
US6652586B2 (en) | 2003-11-25 |
ATE395093T1 (de) | 2008-05-15 |
AU2002316702B2 (en) | 2008-04-03 |
CA2454349A1 (en) | 2003-01-30 |
EP1409036A1 (en) | 2004-04-21 |
KR100920275B1 (ko) | 2009-10-08 |
EP1409036B1 (en) | 2008-05-14 |
US20030028254A1 (en) | 2003-02-06 |
PT1409036E (pt) | 2008-10-28 |
DE60226607D1 (de) | 2008-06-26 |
WO2003008008A1 (en) | 2003-01-30 |
CN1253215C (zh) | 2006-04-26 |
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