DK1406888T3 - Substituerede gamma-lactonforbindelser som NMDA-antagonister - Google Patents
Substituerede gamma-lactonforbindelser som NMDA-antagonisterInfo
- Publication number
- DK1406888T3 DK1406888T3 DK02743260T DK02743260T DK1406888T3 DK 1406888 T3 DK1406888 T3 DK 1406888T3 DK 02743260 T DK02743260 T DK 02743260T DK 02743260 T DK02743260 T DK 02743260T DK 1406888 T3 DK1406888 T3 DK 1406888T3
- Authority
- DK
- Denmark
- Prior art keywords
- nmda antagonists
- lactone compounds
- substituted gamma
- gamma
- substituted
- Prior art date
Links
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 125000000457 gamma-lactone group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10132725A DE10132725A1 (de) | 2001-07-05 | 2001-07-05 | Substituierte γ-Lactonverbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1406888T3 true DK1406888T3 (da) | 2006-09-18 |
Family
ID=7690792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02743260T DK1406888T3 (da) | 2001-07-05 | 2002-07-03 | Substituerede gamma-lactonforbindelser som NMDA-antagonister |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6956055B2 (da) |
| EP (1) | EP1406888B1 (da) |
| AR (1) | AR036130A1 (da) |
| AT (1) | ATE327226T1 (da) |
| CY (1) | CY1105275T1 (da) |
| DE (2) | DE10132725A1 (da) |
| DK (1) | DK1406888T3 (da) |
| ES (1) | ES2266524T3 (da) |
| PE (1) | PE20030275A1 (da) |
| PT (1) | PT1406888E (da) |
| WO (1) | WO2003004483A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002950217A0 (en) | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
| US8214813B2 (en) * | 2007-01-12 | 2012-07-03 | Microsoft Corporation | Code optimization across interfaces |
| US7985375B2 (en) | 2007-04-06 | 2011-07-26 | Qiagen Gaithersburg, Inc. | Sample preparation system and method for processing clinical specimens |
| US8703492B2 (en) | 2007-04-06 | 2014-04-22 | Qiagen Gaithersburg, Inc. | Open platform hybrid manual-automated sample processing system |
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| CN102177436B (zh) | 2008-08-12 | 2015-05-13 | 金帆德尔制药股份有限公司 | 鉴定疾病风险因子的方法 |
| US9953141B2 (en) | 2009-11-18 | 2018-04-24 | Becton, Dickinson And Company | Laboratory central control unit method and system |
| EP3106165B1 (en) | 2011-01-10 | 2019-02-27 | Zinfandel Pharmaceuticals, Inc. | Methods and drug products for treating alzheimer's disease |
| CN113234036B (zh) * | 2021-05-12 | 2023-07-14 | 斯莱普泰(上海)生物医药科技有限公司 | Nmda受体拮抗剂及其用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL93610A0 (en) | 1989-03-08 | 1990-12-23 | Merck Sharp & Dohme | Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them |
| DE19536809A1 (de) | 1995-10-02 | 1997-04-03 | Basf Ag | Heterocyclisch substituierte Salicylsäurederivate |
| GB9617305D0 (en) | 1996-08-17 | 1996-09-25 | Glaxo Wellcome Spa | Heterocyclic compounds |
| GB9706294D0 (en) | 1997-03-26 | 1997-05-14 | Glaxo Wellcome Spa | Heterocyclic compound |
-
2001
- 2001-07-05 DE DE10132725A patent/DE10132725A1/de not_active Withdrawn
-
2002
- 2002-07-03 PT PT02743260T patent/PT1406888E/pt unknown
- 2002-07-03 WO PCT/EP2002/007380 patent/WO2003004483A1/de active IP Right Grant
- 2002-07-03 DE DE50206910T patent/DE50206910D1/de not_active Expired - Lifetime
- 2002-07-03 DK DK02743260T patent/DK1406888T3/da active
- 2002-07-03 ES ES02743260T patent/ES2266524T3/es not_active Expired - Lifetime
- 2002-07-03 AT AT02743260T patent/ATE327226T1/de not_active IP Right Cessation
- 2002-07-03 EP EP02743260A patent/EP1406888B1/de not_active Expired - Lifetime
- 2002-07-04 PE PE2002000601A patent/PE20030275A1/es not_active Application Discontinuation
- 2002-07-05 AR ARP020102526A patent/AR036130A1/es not_active Application Discontinuation
-
2004
- 2004-01-05 US US10/751,741 patent/US6956055B2/en not_active Expired - Fee Related
-
2006
- 2006-08-21 CY CY20061101157T patent/CY1105275T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE10132725A1 (de) | 2006-08-03 |
| AR036130A1 (es) | 2004-08-11 |
| US20040171677A1 (en) | 2004-09-02 |
| ATE327226T1 (de) | 2006-06-15 |
| WO2003004483A1 (de) | 2003-01-16 |
| CY1105275T1 (el) | 2010-03-03 |
| US6956055B2 (en) | 2005-10-18 |
| DE50206910D1 (de) | 2006-06-29 |
| EP1406888A1 (de) | 2004-04-14 |
| EP1406888B1 (de) | 2006-05-24 |
| PE20030275A1 (es) | 2003-04-26 |
| ES2266524T3 (es) | 2007-03-01 |
| PT1406888E (pt) | 2006-10-31 |
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