DK1401839T5 - Antidepressive (SSSRI) azaheterocyclylmethylderivater af 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalen - Google Patents
Antidepressive (SSSRI) azaheterocyclylmethylderivater af 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalenInfo
- Publication number
- DK1401839T5 DK1401839T5 DK02728968T DK02728968T DK1401839T5 DK 1401839 T5 DK1401839 T5 DK 1401839T5 DK 02728968 T DK02728968 T DK 02728968T DK 02728968 T DK02728968 T DK 02728968T DK 1401839 T5 DK1401839 T5 DK 1401839T5
- Authority
- DK
- Denmark
- Prior art keywords
- sssri
- diazacyclopenta
- azaheterocyclyl
- dioxa
- antidepressant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28657901P | 2001-04-26 | 2001-04-26 | |
PCT/US2002/012993 WO2002088131A1 (en) | 2001-04-26 | 2002-04-23 | Antidepressant (sssri) azaheterocyclymethyl derivatives of 7,8-dihydro-3h-t,9-dioxa-1,3-diazacyclopenta[a]naphthalene |
Publications (2)
Publication Number | Publication Date |
---|---|
DK1401839T3 DK1401839T3 (da) | 2005-10-24 |
DK1401839T5 true DK1401839T5 (da) | 2006-03-13 |
Family
ID=23099245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02728968T DK1401839T5 (da) | 2001-04-26 | 2002-04-23 | Antidepressive (SSSRI) azaheterocyclylmethylderivater af 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalen |
Country Status (12)
Country | Link |
---|---|
US (1) | US6573283B2 (es) |
EP (1) | EP1401839B9 (es) |
JP (1) | JP2004527561A (es) |
CN (1) | CN1267434C (es) |
AT (1) | ATE304016T1 (es) |
BR (1) | BR0209408A (es) |
CA (1) | CA2445552A1 (es) |
DE (1) | DE60206048T2 (es) |
DK (1) | DK1401839T5 (es) |
ES (1) | ES2247327T3 (es) |
MX (1) | MXPA03009828A (es) |
WO (1) | WO2002088131A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6927226B2 (en) * | 2001-04-26 | 2005-08-09 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalene |
EP2786995A1 (en) | 2004-03-30 | 2014-10-08 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of JAK and other protein kinases |
WO2008079346A1 (en) | 2006-12-21 | 2008-07-03 | Vertex Pharmaceuticals Incorporated | 5-cyan0-4- (pyrrolo [2, 3b] pyridine-3-yl) -pyrimidine derivatives useful as protein kinase inhibitors |
PE20120508A1 (es) | 2009-06-17 | 2012-05-09 | Vertex Pharma | Inhibidores de la replicacion de los virus de la gripe |
CN103492381A (zh) | 2010-12-16 | 2014-01-01 | 沃泰克斯药物股份有限公司 | 流感病毒复制的抑制剂 |
UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
SG10201804021TA (en) | 2013-11-13 | 2018-07-30 | Vertex Pharma | Methods of preparing inhibitors of influenza viruses replication |
EP3068776B1 (en) | 2013-11-13 | 2019-05-29 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
WO2016183116A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Methods of preparing inhibitors of influenza viruses replication |
JP6857617B2 (ja) | 2015-05-13 | 2021-04-14 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルスの複製の阻害剤 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2075057A1 (en) * | 1990-03-15 | 1991-09-16 | Pharmacia & Upjohn Company Llc | Therapeutically useful heterocyclic indole compounds |
DE4135474A1 (de) | 1991-10-28 | 1993-04-29 | Bayer Ag | 2-aminomethyl-chromane |
DE4140540A1 (de) | 1991-12-09 | 1993-06-17 | Bayer Ag | Neue azaheterocyclylmethyl-chromane |
US5741789A (en) | 1995-01-17 | 1998-04-21 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
US5756532A (en) * | 1995-11-06 | 1998-05-26 | American Home Products Corporation | Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives |
GB9526495D0 (en) * | 1995-12-23 | 1996-02-28 | Knoll Ag | Therapeutic agents |
US5869490A (en) * | 1996-10-15 | 1999-02-09 | American Home Products Corporation | Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one |
ES2196312T3 (es) * | 1996-10-15 | 2003-12-16 | Wyeth Corp | Derivados azaheterociclimetilo de 3,3,9 -tetrahidro-7h 1,4-dioxino (2,3-4) indol-8-0na. |
GB9627005D0 (en) | 1996-12-27 | 1997-02-12 | Knoll Ag | Therapeutic agents |
GB9704948D0 (en) * | 1997-03-11 | 1997-04-30 | Knoll Ag | Therapeutic agents |
US6458802B1 (en) * | 2001-03-14 | 2002-10-01 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline |
-
2002
- 2002-04-23 MX MXPA03009828A patent/MXPA03009828A/es active IP Right Grant
- 2002-04-23 EP EP02728968A patent/EP1401839B9/en not_active Expired - Lifetime
- 2002-04-23 AT AT02728968T patent/ATE304016T1/de not_active IP Right Cessation
- 2002-04-23 BR BR0209408-8A patent/BR0209408A/pt not_active IP Right Cessation
- 2002-04-23 ES ES02728968T patent/ES2247327T3/es not_active Expired - Lifetime
- 2002-04-23 CA CA002445552A patent/CA2445552A1/en not_active Abandoned
- 2002-04-23 WO PCT/US2002/012993 patent/WO2002088131A1/en active IP Right Grant
- 2002-04-23 DK DK02728968T patent/DK1401839T5/da active
- 2002-04-23 CN CNB028088174A patent/CN1267434C/zh not_active Expired - Fee Related
- 2002-04-23 JP JP2002585430A patent/JP2004527561A/ja active Pending
- 2002-04-23 DE DE60206048T patent/DE60206048T2/de not_active Expired - Fee Related
- 2002-04-23 US US10/128,762 patent/US6573283B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
MXPA03009828A (es) | 2005-03-07 |
EP1401839A1 (en) | 2004-03-31 |
DE60206048T2 (de) | 2006-07-13 |
JP2004527561A (ja) | 2004-09-09 |
US20020183351A1 (en) | 2002-12-05 |
CN1535274A (zh) | 2004-10-06 |
EP1401839B1 (en) | 2005-09-07 |
ATE304016T1 (de) | 2005-09-15 |
EP1401839B9 (en) | 2005-11-30 |
CA2445552A1 (en) | 2002-11-07 |
BR0209408A (pt) | 2004-07-06 |
US6573283B2 (en) | 2003-06-03 |
WO2002088131A1 (en) | 2002-11-07 |
DK1401839T3 (da) | 2005-10-24 |
DE60206048D1 (de) | 2005-10-13 |
ES2247327T3 (es) | 2006-03-01 |
CN1267434C (zh) | 2006-08-02 |
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