DK140151B - Fremgangsmåde til fremstilling af et antibiotikum MM 4550 og salte deraf. - Google Patents

Fremgangsmåde til fremstilling af et antibiotikum MM 4550 og salte deraf.

Info

Publication number
DK140151B
DK140151B DK132975AA DK132975A DK140151B DK 140151 B DK140151 B DK 140151B DK 132975A A DK132975A A DK 132975AA DK 132975 A DK132975 A DK 132975A DK 140151 B DK140151 B DK 140151B
Authority
DK
Denmark
Prior art keywords
antibiotic
salts
preparation
Prior art date
Application number
DK132975AA
Other languages
Danish (da)
English (en)
Other versions
DK132975A (fi
DK140151C (fi
Inventor
Denis Butterworth
Martin Cole
John Dick Hood
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of DK132975A publication Critical patent/DK132975A/da
Publication of DK140151B publication Critical patent/DK140151B/da
Application granted granted Critical
Publication of DK140151C publication Critical patent/DK140151C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK132975AA 1974-03-28 1975-03-26 Fremgangsmåde til fremstilling af et antibiotikum MM 4550 og salte deraf. DK140151B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1385574A GB1467413A (en) 1974-03-28 1974-03-28 Antibiotics

Publications (3)

Publication Number Publication Date
DK132975A DK132975A (fi) 1975-09-29
DK140151B true DK140151B (da) 1979-06-25
DK140151C DK140151C (fi) 1979-11-19

Family

ID=10030605

Family Applications (1)

Application Number Title Priority Date Filing Date
DK132975AA DK140151B (da) 1974-03-28 1975-03-26 Fremgangsmåde til fremstilling af et antibiotikum MM 4550 og salte deraf.

Country Status (20)

Country Link
US (1) US4235882A (fi)
JP (1) JPS5820593B2 (fi)
AT (1) AT345453B (fi)
AU (1) AU499460B2 (fi)
BE (1) BE827331A (fi)
CA (1) CA1049532A (fi)
CH (1) CH627494A5 (fi)
DE (1) DE2513855C2 (fi)
DK (1) DK140151B (fi)
ES (1) ES436103A1 (fi)
FI (1) FI55351C (fi)
FR (1) FR2265398B1 (fi)
GB (1) GB1467413A (fi)
IL (1) IL46894A (fi)
NL (1) NL7503669A (fi)
NO (1) NO751074L (fi)
NZ (1) NZ177022A (fi)
SE (1) SE7503535L (fi)
SU (1) SU576965A3 (fi)
ZA (1) ZA751933B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4839352A (en) * 1975-11-21 1989-06-13 Merck & Co., Inc. N-acyl derivatives of thienamycin
US4226870A (en) * 1975-11-21 1980-10-07 Merck & Co., Inc. O-, N- and carboxyl derivatives of thienamycin
GR62185B (en) * 1977-03-31 1979-03-02 Panlabs Inc Preparation process of an antibiotic ps-5 and its derivatives with inhibitory activity of b-lactamase
JPS5414594A (en) * 1977-06-29 1979-02-02 Microbial Chem Res Found Preparation of beta-lactamase inhibiting substance
EP0002564B1 (en) * 1977-11-12 1984-06-20 Beecham Group Plc Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates
US4155912A (en) 1977-12-14 1979-05-22 Bristol-Myers Company 2-Methylpenem-3-carboxylic acid antibiotics
US4182711A (en) 1978-04-27 1980-01-08 Bristol-Myers Company Antibacterial agents of the β-lactam type
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
US4272437A (en) 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
US4282150A (en) 1978-12-18 1981-08-04 Bristol-Myers Company 2,6-Disubstituted penem compounds
US4530791A (en) * 1979-04-16 1985-07-23 Kowa Co., Ltd. β-Lactam antibiotics
US4378314A (en) 1979-09-21 1983-03-29 Bristol Myers Company Antibacterial agents and metal containing azetidinone intermediates therefore
US4374065A (en) 1979-09-21 1983-02-15 Bristol-Myers Company Antibacterial agents of the β-lactam type

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1363075A (en) * 1970-09-17 1974-08-14 Beecham Group Ltd Enzyme inhibitor
US3928569A (en) * 1972-08-09 1975-12-23 Microbial Chem Res Found Two substances inhibiting beta-lactamase and their production
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
DE2513855C2 (de) 1984-04-19
FI750957A (fi) 1975-09-29
SU576965A3 (ru) 1977-10-15
NZ177022A (en) 1981-03-16
GB1467413A (en) 1977-03-16
CA1049532A (en) 1979-02-27
BE827331A (fr) 1975-09-29
JPS5820593B2 (ja) 1983-04-23
FI55351B (fi) 1979-03-30
US4235882A (en) 1980-11-25
NL7503669A (nl) 1975-09-30
FR2265398A1 (fi) 1975-10-24
IL46894A (en) 1978-07-31
AU499460B2 (en) 1979-04-26
ZA751933B (en) 1976-03-31
JPS50135294A (fi) 1975-10-27
IL46894A0 (en) 1975-05-22
SE7503535L (sv) 1975-09-29
ES436103A1 (es) 1977-01-16
CH627494A5 (de) 1982-01-15
FR2265398B1 (fi) 1978-11-24
AT345453B (de) 1978-09-25
DK132975A (fi) 1975-09-29
NO751074L (fi) 1975-09-30
ATA228275A (de) 1978-01-15
DE2513855A1 (de) 1975-10-02
DK140151C (fi) 1979-11-19
AU7960075A (en) 1976-09-30
FI55351C (fi) 1979-07-10

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