DK1392700T3 - Antidepressive azaheterocyclylmethylderivater af 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalen - Google Patents

Antidepressive azaheterocyclylmethylderivater af 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalen

Info

Publication number
DK1392700T3
DK1392700T3 DK02766816T DK02766816T DK1392700T3 DK 1392700 T3 DK1392700 T3 DK 1392700T3 DK 02766816 T DK02766816 T DK 02766816T DK 02766816 T DK02766816 T DK 02766816T DK 1392700 T3 DK1392700 T3 DK 1392700T3
Authority
DK
Denmark
Prior art keywords
azaheterocyclyl
trioxa
antidepressant
cyclopenta
aza
Prior art date
Application number
DK02766816T
Other languages
Danish (da)
English (en)
Inventor
Megan Tran
Gary Paul Stack
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1392700T3 publication Critical patent/DK1392700T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK02766816T 2001-04-30 2002-04-25 Antidepressive azaheterocyclylmethylderivater af 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalen DK1392700T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28744901P 2001-04-30 2001-04-30
PCT/US2002/013117 WO2002088140A1 (en) 2001-04-30 2002-04-25 Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene

Publications (1)

Publication Number Publication Date
DK1392700T3 true DK1392700T3 (da) 2004-10-25

Family

ID=23102960

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02766816T DK1392700T3 (da) 2001-04-30 2002-04-25 Antidepressive azaheterocyclylmethylderivater af 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalen

Country Status (14)

Country Link
US (2) US6525075B2 (es)
EP (1) EP1392700B1 (es)
JP (1) JP2004528352A (es)
CN (1) CN1256337C (es)
AT (1) ATE277934T1 (es)
BR (1) BR0209407A (es)
CA (1) CA2445859A1 (es)
DE (1) DE60201447T2 (es)
DK (1) DK1392700T3 (es)
ES (1) ES2225798T3 (es)
MX (1) MXPA03009829A (es)
PT (1) PT1392700E (es)
TR (1) TR200402753T4 (es)
WO (1) WO2002088140A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6815448B2 (en) * 2001-05-07 2004-11-09 Wyeth Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT1A antagonists
US6800637B2 (en) * 2002-09-12 2004-10-05 Wyeth Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines
CA2560454C (en) 2004-03-30 2013-05-21 Vertex Pharmaceuticals Incorporated Azaindoles useful as inhibitors of jak and other protein kinases
US8247421B2 (en) 2006-12-21 2012-08-21 Vertex Pharmaceuticals Incorporated 5-cyano-4-(pyrrolo [2,3B] pyridine-3-yl)-pyrimidine derivatives useful as protein kinase inhibitors
CN104940202B (zh) 2009-06-17 2018-10-16 沃泰克斯药物股份有限公司 流感病毒复制抑制剂
CN103492381A (zh) 2010-12-16 2014-01-01 沃泰克斯药物股份有限公司 流感病毒复制的抑制剂
UA118010C2 (uk) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед Інгібітори реплікації вірусів грипу
PL3068782T3 (pl) 2013-11-13 2018-12-31 Vertex Pharmaceuticals Incorporated Sposoby wytwarzania inhibitorów replikacji wirusów grypy
NZ719729A (en) 2013-11-13 2022-04-29 Vertex Pharma Inhibitors of influenza viruses replication
JP6704416B2 (ja) 2015-05-13 2020-06-03 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ インフルエンザウイルスの複製の阻害剤を調製する方法
MA42422A (fr) 2015-05-13 2018-05-23 Vertex Pharma Inhibiteurs de la réplication des virus de la grippe

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05505599A (ja) 1990-03-15 1993-08-19 ジ・アップジョン・カンパニー 治療上有用な複素環インドール化合物類
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
GB9526495D0 (en) 1995-12-23 1996-02-28 Knoll Ag Therapeutic agents
DK0932609T3 (da) * 1996-10-15 2003-09-01 Wyeth Corp Azaheterocyclomethylderivater af 2,3,8,9-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-on
US5869490A (en) 1996-10-15 1999-02-09 American Home Products Corporation Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one
GB9627005D0 (en) 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents
GB9704948D0 (en) * 1997-03-11 1997-04-30 Knoll Ag Therapeutic agents
WO1999010346A1 (en) * 1997-08-22 1999-03-04 Eli Lilly And Company Limited Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands
US6458802B1 (en) * 2001-03-14 2002-10-01 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline

Also Published As

Publication number Publication date
US6613913B2 (en) 2003-09-02
JP2004528352A (ja) 2004-09-16
EP1392700B1 (en) 2004-09-29
CN1256337C (zh) 2006-05-17
WO2002088140A1 (en) 2002-11-07
CN1503799A (zh) 2004-06-09
US20020183354A1 (en) 2002-12-05
US20030109562A1 (en) 2003-06-12
ATE277934T1 (de) 2004-10-15
DE60201447D1 (de) 2004-11-04
BR0209407A (pt) 2004-07-06
CA2445859A1 (en) 2002-11-07
EP1392700A1 (en) 2004-03-03
PT1392700E (pt) 2004-12-31
MXPA03009829A (es) 2005-03-07
TR200402753T4 (tr) 2004-11-22
ES2225798T3 (es) 2005-03-16
DE60201447T2 (de) 2006-02-23
US6525075B2 (en) 2003-02-25

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