DK138501C - Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner - Google Patents

Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Info

Publication number
DK138501C
DK138501C DK588775A DK588775A DK138501C DK 138501 C DK138501 C DK 138501C DK 588775 A DK588775 A DK 588775A DK 588775 A DK588775 A DK 588775A DK 138501 C DK138501 C DK 138501C
Authority
DK
Denmark
Prior art keywords
dioner
3alfa
5alfa
pregnan
homo
Prior art date
Application number
DK588775A
Other languages
English (en)
Other versions
DK138501B (da
DK588775A (da
Inventor
U Kerb
R Wiechert
H Wachtel
O Engelfried
K Kieslich
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742461312 external-priority patent/DE2461312A1/de
Priority claimed from DE19752506688 external-priority patent/DE2506688A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK588775A publication Critical patent/DK588775A/da
Publication of DK138501B publication Critical patent/DK138501B/da
Application granted granted Critical
Publication of DK138501C publication Critical patent/DK138501C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK588775A 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner DK138501C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742461312 DE2461312A1 (de) 1974-12-23 1974-12-23 D-homo-20-keto-pregnane und verfahren zu ihrer herstellung
DE19752506688 DE2506688A1 (de) 1975-02-14 1975-02-14 D-homo-19-nor-20-ketopregnane und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
DK588775A DK588775A (da) 1976-06-24
DK138501B DK138501B (da) 1978-09-18
DK138501C true DK138501C (da) 1979-02-19

Family

ID=25768157

Family Applications (1)

Application Number Title Priority Date Filing Date
DK588775A DK138501C (da) 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Country Status (13)

Country Link
US (1) US4056633A (da)
JP (1) JPS5188953A (da)
AU (1) AU501685B2 (da)
CA (1) CA1051868A (da)
DD (1) DD123329A5 (da)
DK (1) DK138501C (da)
ES (1) ES443825A1 (da)
FR (1) FR2295739A1 (da)
GB (1) GB1538869A (da)
IL (1) IL48628A0 (da)
LU (1) LU74087A1 (da)
NL (1) NL7514976A (da)
SE (1) SE7514514L (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104306A (en) * 1976-05-05 1978-08-01 Abbott Laboratories 12A-Deoxy chelocardin
US5439900A (en) * 1993-02-25 1995-08-08 Bukusoglu; Cuneyt Methods and compositions for providing analgesia and enhanced anesthesia
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
MXPA05001857A (es) * 2002-08-16 2005-06-03 Upjohn Co Intermedios esteroideos de 5-androsten-38-ol y procedimientos para su preparacion.
HRP20190232T1 (hr) 2013-04-17 2019-03-22 Sage Therapeutics, Inc. 19-nor c3,3-disupstituirani c21-n-pirazolil steroidi i postupci za njihovu upotrebu
HRP20200995T1 (hr) 2013-04-17 2020-11-27 Sage Therapeutics, Inc. 19-nor neuroaktivni steroidi za metode liječenja
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
SMT202100229T1 (it) 2013-07-19 2021-05-07 Sage Therapeutics Inc Steroidi neuroattivi, composizioni e loro usi
SMT202100048T1 (it) 2013-08-23 2021-03-15 Sage Therapeutics Inc Steroidi neuroattivi, composizioni e loro usi
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
JP6742308B2 (ja) 2014-10-16 2020-08-19 セージ セラピューティクス， インコーポレイテッド Ｃｎｓ障害を処置するための組成物および方法
AU2015331749A1 (en) 2014-10-16 2017-05-04 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
ES2793237T3 (es) 2014-11-27 2020-11-13 Sage Therapeutics Inc Composiciones y métodos para el tratamiento de trastornos del SNC
SI3250210T1 (sl) 2015-01-26 2021-07-30 Sage Therapeutics, Inc. Sestavki in metode za zdravljenje CNS motenj
US10329320B2 (en) 2015-02-20 2019-06-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
AU2017296295B2 (en) 2016-07-11 2022-02-24 Sage Therapeutics, Inc. C7, C12, and C16 substituted neuroactive steroids and their methods of use
CN109689673B (zh) 2016-07-11 2023-03-14 萨奇治疗股份有限公司 C17、c20和c21取代的神经活性类固醇及其使用方法
AR114044A1 (es) * 2017-12-22 2020-07-15 Sage Therapeutics Inc Composiciones y métodos para el tratamiento de trastornos en el sistema nervioso central
JP7538040B2 (ja) * 2018-01-12 2024-08-21 セージ セラピューティクス， インコーポレイテッド ＣＮＳ障害の処置における使用のためのアザ、オキサ、およびチア－プレグナン－２０－オン－３α－オール化合物
BR112021010996A2 (pt) 2018-12-05 2021-08-31 Sage Therapeutics, Inc. Esteroides neuroativos e seus métodos de uso
KR102821994B1 (ko) * 2019-01-08 2025-06-19 쳉두 캉홍 파마슈티칼 코., 엘티디. 스테로이드 화합물, 및 이의 용도와 제조방법
CN114206900A (zh) 2019-05-31 2022-03-18 萨奇治疗股份有限公司 神经活性类固醇及其组合物
AU2020302748A1 (en) 2019-06-27 2022-01-06 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
CN114787174A (zh) * 2019-06-27 2022-07-22 萨奇治疗股份有限公司 用于治疗cns病症的组合物和方法
CN114729000A (zh) * 2019-06-27 2022-07-08 萨奇治疗股份有限公司 用于治疗cns病症的化合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876705A (en) * 1972-06-12 1975-04-08 Univ New Brunswick Steroid total synthesis and intermediates

Also Published As

Publication number Publication date
ES443825A1 (es) 1977-05-01
SE7514514L (sv) 1976-06-24
GB1538869A (en) 1979-01-24
AU8763775A (en) 1977-06-23
LU74087A1 (da) 1976-07-20
IL48628A0 (en) 1976-02-29
CA1051868A (en) 1979-04-03
JPS5188953A (en) 1976-08-04
DK138501B (da) 1978-09-18
FR2295739A1 (fr) 1976-07-23
NL7514976A (nl) 1976-06-25
US4056633A (en) 1977-11-01
DK588775A (da) 1976-06-24
AU501685B2 (en) 1979-06-28
DD123329A5 (da) 1976-12-12

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