DK138501C - Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner - Google Patents

Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Info

Publication number
DK138501C
DK138501C DK588775A DK588775A DK138501C DK 138501 C DK138501 C DK 138501C DK 588775 A DK588775 A DK 588775A DK 588775 A DK588775 A DK 588775A DK 138501 C DK138501 C DK 138501C
Authority
DK
Denmark
Prior art keywords
dioner
3alfa
5alfa
pregnan
homo
Prior art date
Application number
DK588775A
Other languages
Danish (da)
English (en)
Other versions
DK138501B (da
DK588775A (da
Inventor
U Kerb
R Wiechert
H Wachtel
O Engelfried
K Kieslich
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742461312 external-priority patent/DE2461312A1/de
Priority claimed from DE19752506688 external-priority patent/DE2506688A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK588775A publication Critical patent/DK588775A/da
Publication of DK138501B publication Critical patent/DK138501B/da
Application granted granted Critical
Publication of DK138501C publication Critical patent/DK138501C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK588775A 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner DK138501C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742461312 DE2461312A1 (de) 1974-12-23 1974-12-23 D-homo-20-keto-pregnane und verfahren zu ihrer herstellung
DE19752506688 DE2506688A1 (de) 1975-02-14 1975-02-14 D-homo-19-nor-20-ketopregnane und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
DK588775A DK588775A (da) 1976-06-24
DK138501B DK138501B (da) 1978-09-18
DK138501C true DK138501C (da) 1979-02-19

Family

ID=25768157

Family Applications (1)

Application Number Title Priority Date Filing Date
DK588775A DK138501C (da) 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Country Status (13)

Country Link
US (1) US4056633A (cs)
JP (1) JPS5188953A (cs)
AU (1) AU501685B2 (cs)
CA (1) CA1051868A (cs)
DD (1) DD123329A5 (cs)
DK (1) DK138501C (cs)
ES (1) ES443825A1 (cs)
FR (1) FR2295739A1 (cs)
GB (1) GB1538869A (cs)
IL (1) IL48628A0 (cs)
LU (1) LU74087A1 (cs)
NL (1) NL7514976A (cs)
SE (1) SE7514514L (cs)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104306A (en) * 1976-05-05 1978-08-01 Abbott Laboratories 12A-Deoxy chelocardin
US5439900A (en) * 1993-02-25 1995-08-08 Bukusoglu; Cuneyt Methods and compositions for providing analgesia and enhanced anesthesia
AU2003285485A1 (en) * 2002-08-16 2004-03-03 Pharmacia & Upjohn Company Llc 5 ANDROSTEN-3Beta-OL STEROID INTERMEDIATES AND PROCESSES FOR THEIR PREPARATION
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
SI3498725T1 (sl) 2013-04-17 2021-11-30 Sage Therapeutics, Inc. 19-NOR C3,3-disubstituiran C21-N-pirazolilni steroid za uporabo v terapiji
JP6239091B2 (ja) 2013-04-17 2017-11-29 セージ セラピューティクス， インコーポレイテッド １９−ノル神経刺激性ステロイドおよびその使用方法
CA2918735C (en) 2013-07-19 2023-08-01 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
EP3035940B1 (en) 2013-08-23 2018-10-17 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
HRP20201216T1 (hr) 2014-10-16 2020-12-11 Sage Therapeutics, Inc. PRIPRAVCI I POSTUPCI ZA LIJEČENJE POREMEĆAJA CNS-a
MX2021004492A (es) 2014-10-16 2022-12-05 Sage Therapeutics Inc Composiciones para el tratamiento de trastornos del snc.
JP6893173B2 (ja) 2014-11-27 2021-06-23 セージ セラピューティクス， インコーポレイテッド Ｃｎｓ障害を処置するための組成物および方法
PL3250210T3 (pl) 2015-01-26 2021-07-26 Sage Therapeutics, Inc. Kompozycje i sposoby leczenia zaburzeń OUN
JP6875996B2 (ja) 2015-02-20 2021-05-26 セージ セラピューティクス， インコーポレイテッド 神経刺激性ステロイド、組成物、およびその使用
CA3030420A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
JP7049313B2 (ja) 2016-07-11 2022-04-06 セージ セラピューティクス， インコーポレイテッド Ｃ１７、ｃ２０、およびｃ２１置換神経刺激性ステロイドおよびそれらの使用方法
CN118085004A (zh) * 2017-12-22 2024-05-28 萨奇治疗股份有限公司 治疗中枢神经系统疾病的组合物和方法
WO2020118060A1 (en) 2018-12-05 2020-06-11 Sage Therapeutics, Inc. Neuroactive steroids and their methods of use
US12415830B2 (en) * 2019-01-08 2025-09-16 Chengdu kanghong pharmaceutical co ltd Steroid compound, and use thereof and preparation method therefor
WO2020243488A1 (en) 2019-05-31 2020-12-03 Sage Therapeutics, Inc. Neuroactive steroids and compositions thereof
CN114787174A (zh) * 2019-06-27 2022-07-22 萨奇治疗股份有限公司 用于治疗cns病症的组合物和方法
BR112021026445A2 (pt) * 2019-06-27 2022-03-08 Sage Therapeutics Inc Composições e métodos para tratar distúrbios de cns

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876705A (en) * 1972-06-12 1975-04-08 Univ New Brunswick Steroid total synthesis and intermediates

Also Published As

Publication number Publication date
NL7514976A (nl) 1976-06-25
ES443825A1 (es) 1977-05-01
SE7514514L (sv) 1976-06-24
IL48628A0 (en) 1976-02-29
FR2295739A1 (fr) 1976-07-23
LU74087A1 (cs) 1976-07-20
DD123329A5 (cs) 1976-12-12
US4056633A (en) 1977-11-01
DK138501B (da) 1978-09-18
CA1051868A (en) 1979-04-03
AU501685B2 (en) 1979-06-28
JPS5188953A (en) 1976-08-04
DK588775A (da) 1976-06-24
AU8763775A (en) 1977-06-23
GB1538869A (en) 1979-01-24

Similar Documents

Publication Publication Date Title
DK138501C (da) Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner
DK144298C (da) Fremgangsmaade til fremstilling af alkyl-tert-butylethere
DK134282C (da) Analogifremgangsmade til fremstilling af substituerede phenylguanidiner
DK138749C (da) Analogifremgangsmaade til fremstilling af 18-methyl-4,15-oestradiener
DK385475A (da) Fremgangsmade til fremstilling af secoprostaglandiner
DK179675A (da) Fremgangsmade til fremstilling af 6-amino-5-r3-2,4-diaminopyrimidin-3-oxider
DK136729C (da) Analogifremgangsmaade til fremstilling af 1alfa,17beta-dihydroxy-17beta-alkynyl-4-oestren-3-oner
DK141849C (da) Fremgangsmaade til fremstilling af slagseje vinylaromat-podecopolymere
DK135378C (da) Analogifremgangsmade til fremstilling af 7alfa-hydroxylerede 17alfa-ethinylostradioler
DK356375A (da) Fremgangsmade til fremstilling af 2-thiol-4,5-diphenyloxazol-s-derivater
DK574075A (da) Fremgangsmade til fremstilling af 2-methoxybenzamider
DK206375A (da) Fremgangsmade til fremstilling af thiaprostaglandiner
DK528475A (da) Fremgangsmade til fremstilling af tetramethylethylendiamin
DK390975A (da) Fremgangsmade til fremstilling af omega-nor-cycloalkyl-13,14-dehydroprostaglandiner
DK583775A (da) Fremgangsmade til fremstilling af 3-fluorbenzodiazepiner
DK543875A (da) Fremgangsmade til fremstilling af hydroxyphenylacetonitriler
DK137539C (da) Fremgangsmaade til fremstilling af 11beta-fluor-4-androsten-3-oner
DK132661C (da) Fremgangsmade til fremstilling af 17-acylestere af 17alfa,21-dihydroxysteroider af pregnanrekken
DK593575A (da) Fremgangsmade til fremstilling af trichlorethylchlorformiat
DK137185B (da) Analogifremgangsmade til fremstilling af tiofenderivater
DK139138C (da) Analogifremgangsmaade til fremstilling af 1-aryluraciler
DK348575A (da) Fremgangsmade til fremstilling af 9,11,15-trihydroxy-13,14-dehydro-prostaglandiner
DK137721C (da) Fremgangsmaade til fremstilling af alfa-oxothiodimethylamider
DK543975A (da) Fremgangsmade til fremstilling af 4-hydroxy-3-methoxyphenylacetonitril
DK396175A (da) Fremgangsmade til fremstilling af benzylaminoalkansyrer