DK138501C - Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner - Google Patents

Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Info

Publication number
DK138501C
DK138501C DK588775A DK588775A DK138501C DK 138501 C DK138501 C DK 138501C DK 588775 A DK588775 A DK 588775A DK 588775 A DK588775 A DK 588775A DK 138501 C DK138501 C DK 138501C
Authority
DK
Denmark
Prior art keywords
dioner
3alfa
5alfa
pregnan
homo
Prior art date
Application number
DK588775A
Other languages
Danish (da)
English (en)
Other versions
DK138501B (da
DK588775A (da
Inventor
U Kerb
R Wiechert
H Wachtel
O Engelfried
K Kieslich
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742461312 external-priority patent/DE2461312A1/de
Priority claimed from DE19752506688 external-priority patent/DE2506688A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK588775A publication Critical patent/DK588775A/da
Publication of DK138501B publication Critical patent/DK138501B/da
Application granted granted Critical
Publication of DK138501C publication Critical patent/DK138501C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK588775A 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner DK138501C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742461312 DE2461312A1 (de) 1974-12-23 1974-12-23 D-homo-20-keto-pregnane und verfahren zu ihrer herstellung
DE19752506688 DE2506688A1 (de) 1975-02-14 1975-02-14 D-homo-19-nor-20-ketopregnane und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
DK588775A DK588775A (da) 1976-06-24
DK138501B DK138501B (da) 1978-09-18
DK138501C true DK138501C (da) 1979-02-19

Family

ID=25768157

Family Applications (1)

Application Number Title Priority Date Filing Date
DK588775A DK138501C (da) 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Country Status (13)

Country Link
US (1) US4056633A (OSRAM)
JP (1) JPS5188953A (OSRAM)
AU (1) AU501685B2 (OSRAM)
CA (1) CA1051868A (OSRAM)
DD (1) DD123329A5 (OSRAM)
DK (1) DK138501C (OSRAM)
ES (1) ES443825A1 (OSRAM)
FR (1) FR2295739A1 (OSRAM)
GB (1) GB1538869A (OSRAM)
IL (1) IL48628A0 (OSRAM)
LU (1) LU74087A1 (OSRAM)
NL (1) NL7514976A (OSRAM)
SE (1) SE7514514L (OSRAM)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104306A (en) * 1976-05-05 1978-08-01 Abbott Laboratories 12A-Deoxy chelocardin
US5439900A (en) * 1993-02-25 1995-08-08 Bukusoglu; Cuneyt Methods and compositions for providing analgesia and enhanced anesthesia
ATE339437T1 (de) * 2002-08-16 2006-10-15 Pharmacia & Upjohn Co Llc 5-androsten-3-olsteroidzwischenprodukte und verfahren zu deren herstellung
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
SI2986623T1 (sl) 2013-04-17 2019-03-29 Sage Therapeutics, Inc. 19-NOR C3,3-disubstituirani C21-N-pirazolil steroidi in metode njhove uporabe
RS60420B1 (sr) 2013-04-17 2020-07-31 Sage Therapeutics Inc 19-nor neuroaktivni steroidi za metode lečenja
PT3021852T (pt) 2013-07-19 2021-04-21 Sage Therapeutics Inc Esteroides neuroativos, composições e utilizações das mesmas
JP6466942B2 (ja) 2013-08-23 2019-02-06 セージ セラピューティクス， インコーポレイテッド 向神経活性ステロイド、組成物、及びその使用
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
MX384728B (es) 2014-10-16 2025-03-14 Sage Therapeutics Inc Composiciones para el tratamiento de trastornos del snc.
LT3206493T (lt) 2014-10-16 2020-08-25 Sage Therapeutics, Inc. Kompozicijos ir būdai, skirti cns sutrikimams gydyti
HUE049014T2 (hu) 2014-11-27 2020-09-28 Sage Therapeutics Inc Készítmények és módszerek a központi idegrendszer rendellenességeinek kezelésére
WO2016123056A1 (en) 2015-01-26 2016-08-04 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
EP3258939B1 (en) 2015-02-20 2022-09-07 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
DK3481844T3 (da) 2016-07-11 2024-07-22 Sage Therapeutics Inc C7, C12 og C16 substituerede neuroaktive steroider og disses fremgangsmåder til anvendelse
IL264129B2 (en) 2016-07-11 2024-05-01 Sage Therapeutics Inc C20, C17 and C21 converted neuroactive steroids and methods of using them
BR112020012761A2 (pt) * 2017-12-22 2021-02-17 Sage Therapeutics, Inc. composições e métodos para o tratamento de distúrbios do snc
JP7538040B2 (ja) * 2018-01-12 2024-08-21 セージ セラピューティクス， インコーポレイテッド ＣＮＳ障害の処置における使用のためのアザ、オキサ、およびチア－プレグナン－２０－オン－３α－オール化合物
CN113383004A (zh) 2018-12-05 2021-09-10 萨奇治疗股份有限公司 神经活性类固醇及其使用方法
CN111410678B (zh) 2019-01-08 2023-02-28 成都康弘药业集团股份有限公司 甾体类化合物、用途及其制备方法
EP3976628A1 (en) 2019-05-31 2022-04-06 Sage Therapeutics, Inc. Neuroactive steroids and compositions thereof
CA3143545A1 (en) * 2019-06-27 2020-12-30 Sage Therapeutics, Inc. Compounds for treating cns disorders
AU2020304673A1 (en) * 2019-06-27 2022-01-20 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876705A (en) * 1972-06-12 1975-04-08 Univ New Brunswick Steroid total synthesis and intermediates

Also Published As

Publication number Publication date
CA1051868A (en) 1979-04-03
US4056633A (en) 1977-11-01
LU74087A1 (OSRAM) 1976-07-20
NL7514976A (nl) 1976-06-25
GB1538869A (en) 1979-01-24
ES443825A1 (es) 1977-05-01
DK138501B (da) 1978-09-18
IL48628A0 (en) 1976-02-29
DK588775A (da) 1976-06-24
AU8763775A (en) 1977-06-23
JPS5188953A (en) 1976-08-04
AU501685B2 (en) 1979-06-28
SE7514514L (sv) 1976-06-24
FR2295739A1 (fr) 1976-07-23
DD123329A5 (OSRAM) 1976-12-12

Similar Documents

Publication Publication Date Title
DK138501C (da) Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner
DK144298C (da) Fremgangsmaade til fremstilling af alkyl-tert-butylethere
DK134282C (da) Analogifremgangsmade til fremstilling af substituerede phenylguanidiner
DK138749C (da) Analogifremgangsmaade til fremstilling af 18-methyl-4,15-oestradiener
DK385475A (da) Fremgangsmade til fremstilling af secoprostaglandiner
DK179675A (da) Fremgangsmade til fremstilling af 6-amino-5-r3-2,4-diaminopyrimidin-3-oxider
DK136729C (da) Analogifremgangsmaade til fremstilling af 1alfa,17beta-dihydroxy-17beta-alkynyl-4-oestren-3-oner
DK141849C (da) Fremgangsmaade til fremstilling af slagseje vinylaromat-podecopolymere
DK135378C (da) Analogifremgangsmade til fremstilling af 7alfa-hydroxylerede 17alfa-ethinylostradioler
DK356375A (da) Fremgangsmade til fremstilling af 2-thiol-4,5-diphenyloxazol-s-derivater
DK206375A (da) Fremgangsmade til fremstilling af thiaprostaglandiner
DK574075A (da) Fremgangsmade til fremstilling af 2-methoxybenzamider
DK583775A (da) Fremgangsmade til fremstilling af 3-fluorbenzodiazepiner
DK528475A (da) Fremgangsmade til fremstilling af tetramethylethylendiamin
DK390975A (da) Fremgangsmade til fremstilling af omega-nor-cycloalkyl-13,14-dehydroprostaglandiner
DK543875A (da) Fremgangsmade til fremstilling af hydroxyphenylacetonitriler
DK137539C (da) Fremgangsmaade til fremstilling af 11beta-fluor-4-androsten-3-oner
DK132661C (da) Fremgangsmade til fremstilling af 17-acylestere af 17alfa,21-dihydroxysteroider af pregnanrekken
DK593575A (da) Fremgangsmade til fremstilling af trichlorethylchlorformiat
DK137185B (da) Analogifremgangsmade til fremstilling af tiofenderivater
DK139138C (da) Analogifremgangsmaade til fremstilling af 1-aryluraciler
DK348575A (da) Fremgangsmade til fremstilling af 9,11,15-trihydroxy-13,14-dehydro-prostaglandiner
DK137721C (da) Fremgangsmaade til fremstilling af alfa-oxothiodimethylamider
DK543975A (da) Fremgangsmade til fremstilling af 4-hydroxy-3-methoxyphenylacetonitril
DK396175A (da) Fremgangsmade til fremstilling af benzylaminoalkansyrer