DK1372689T3 - Anvendelse af inhibitorer af ikk-beta og metoder til opsporing af disse inhibitorer - Google Patents

Anvendelse af inhibitorer af ikk-beta og metoder til opsporing af disse inhibitorer

Info

Publication number
DK1372689T3
DK1372689T3 DK02730066T DK02730066T DK1372689T3 DK 1372689 T3 DK1372689 T3 DK 1372689T3 DK 02730066 T DK02730066 T DK 02730066T DK 02730066 T DK02730066 T DK 02730066T DK 1372689 T3 DK1372689 T3 DK 1372689T3
Authority
DK
Denmark
Prior art keywords
inhibitors
beta
detecting
methods
endothelial cells
Prior art date
Application number
DK02730066T
Other languages
English (en)
Inventor
Martin Ungerer
Korbinian Brand
Meinrad Gawaz
Original Assignee
Procorde Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procorde Gmbh filed Critical Procorde Gmbh
Application granted granted Critical
Publication of DK1372689T3 publication Critical patent/DK1372689T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5064Endothelial cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/521Chemokines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK02730066T 2001-03-27 2002-03-26 Anvendelse af inhibitorer af ikk-beta og metoder til opsporing af disse inhibitorer DK1372689T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10115073A DE10115073A1 (de) 2001-03-27 2001-03-27 Verwendung von Inhibitoren von IKK-ß und Verfahren zum Auffinden solcher Inhibitoren

Publications (1)

Publication Number Publication Date
DK1372689T3 true DK1372689T3 (da) 2004-08-30

Family

ID=7679248

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02730066T DK1372689T3 (da) 2001-03-27 2002-03-26 Anvendelse af inhibitorer af ikk-beta og metoder til opsporing af disse inhibitorer

Country Status (9)

Country Link
US (1) US20040241166A1 (da)
EP (1) EP1372689B1 (da)
JP (1) JP2004532204A (da)
AT (1) ATE270896T1 (da)
AU (1) AU2002302472A1 (da)
DE (2) DE10115073A1 (da)
DK (1) DK1372689T3 (da)
ES (1) ES2224065T3 (da)
WO (1) WO2002076482A2 (da)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401730A (en) * 1990-07-06 1995-03-28 The Hope Heart Institute Method for reducing platelet aggregation
US5851812A (en) * 1997-07-01 1998-12-22 Tularik Inc. IKK-β proteins, nucleic acids and methods
US6121249A (en) * 1998-07-01 2000-09-19 Donald L. Weissman Treatment and prevention of cardiovascular diseases with help of aspirin, antioxidants, niacin, and certain B vitamins
DE19928424A1 (de) * 1999-06-23 2000-12-28 Aventis Pharma Gmbh Substituierte Benzimidazole
IL147184A0 (en) * 1999-06-23 2002-08-14 Aventis Pharma Gmbh Substituted benzimidazole
US6916843B1 (en) * 1999-08-11 2005-07-12 The United States Of America As Represented By The Department Of Health And Human Services Anti-inflammatory actions of cytochrome P450 expoxygenase-derived eicosanoids

Also Published As

Publication number Publication date
ES2224065T3 (es) 2005-03-01
US20040241166A1 (en) 2004-12-02
DE10115073A1 (de) 2002-10-10
AU2002302472A1 (en) 2002-10-08
ATE270896T1 (de) 2004-07-15
DE50200635D1 (de) 2004-08-19
JP2004532204A (ja) 2004-10-21
EP1372689A2 (de) 2004-01-02
WO2002076482A3 (de) 2003-09-25
WO2002076482A2 (de) 2002-10-03
EP1372689B1 (de) 2004-07-14
WO2002076482B1 (de) 2003-11-06

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