DK1370663T3 - Mikrobiologisk metode til fremstilling af L-carnitin - Google Patents

Mikrobiologisk metode til fremstilling af L-carnitin

Info

Publication number
DK1370663T3
DK1370663T3 DK02712878T DK02712878T DK1370663T3 DK 1370663 T3 DK1370663 T3 DK 1370663T3 DK 02712878 T DK02712878 T DK 02712878T DK 02712878 T DK02712878 T DK 02712878T DK 1370663 T3 DK1370663 T3 DK 1370663T3
Authority
DK
Denmark
Prior art keywords
carnitine
betaine
hydrolases
preparing
ester
Prior art date
Application number
DK02712878T
Other languages
English (en)
Inventor
Uwe Bornscheuer
Anna Musidlowska
Josef Werlen
Thomas Zimmermann
Benno Tscherry
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Application granted granted Critical
Publication of DK1370663T3 publication Critical patent/DK1370663T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/007—Carnitine; Butyrobetaine; Crotonobetaine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/41—Rhizobium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK02712878T 2001-01-31 2002-01-31 Mikrobiologisk metode til fremstilling af L-carnitin DK1370663T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01102214 2001-01-31
PCT/EP2002/001009 WO2002061094A2 (de) 2001-01-31 2002-01-31 Mikrobiologisches verfahren zur herstellung von l-carnitin

Publications (1)

Publication Number Publication Date
DK1370663T3 true DK1370663T3 (da) 2007-07-02

Family

ID=8176358

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02712878T DK1370663T3 (da) 2001-01-31 2002-01-31 Mikrobiologisk metode til fremstilling af L-carnitin

Country Status (7)

Country Link
EP (1) EP1370663B1 (da)
CN (1) CN1233832C (da)
AT (1) ATE356214T1 (da)
DE (1) DE50209655D1 (da)
DK (1) DK1370663T3 (da)
ES (1) ES2282399T3 (da)
WO (1) WO2002061094A2 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9084431B2 (en) 2005-07-05 2015-07-21 Lonza Ltd. Spray-Drying process for producing a dry caritine powder or granulate
EP2325164A1 (en) * 2009-11-18 2011-05-25 Lonza Ltd. Methods for the production of l-carnitine
CN107879944B (zh) * 2017-10-30 2020-05-22 杭州海尔希畜牧科技有限公司 一种制备丁基甜菜碱的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI86889C (fi) * 1984-03-29 1992-10-26 Lonza Ag Foerfarande foer framstaellning av av l-karnitin pao mikrobiologiskt saett
JPH0291049A (ja) * 1988-09-21 1990-03-30 Lonza Ag ｒ―ブチロベタインの製造方法
RU2099418C1 (ru) * 1991-11-21 1997-12-20 Лонца Аг Фрагмент днк, обеспечивающий использование бетаина, рекомбинантная плазмидная днк с фрагментом днк, обеспечивающим использование бетаина, штамм бактерий rhizobium/agrobacterium, предназначенный для стабильного хранения плазмиды с фрагментом днк, способ получения штамма бактерий
KR100346293B1 (ko) * 1993-10-08 2002-11-30 론자 아게 부티로베타인/크로토노베타인-l-카르니틴대사유전자와l-카르니틴의미생물학적제조에사용되는그것의용도

Also Published As

Publication number Publication date
ATE356214T1 (de) 2007-03-15
ES2282399T3 (es) 2007-10-16
WO2002061094A2 (de) 2002-08-08
EP1370663A2 (de) 2003-12-17
WO2002061094A3 (de) 2003-10-02
CN1489629A (zh) 2004-04-14
DE50209655D1 (de) 2007-04-19
CN1233832C (zh) 2005-12-28
EP1370663B1 (de) 2007-03-07

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