DK136976B - Analogifremgangsmåde til fremstilling af 2-(alfa-(3-trifluormethylphenoxy)-4-chlorbenzyl)-2-oxazolin eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af 2-(alfa-(3-trifluormethylphenoxy)-4-chlorbenzyl)-2-oxazolin eller syreadditionssalte deraf.

Info

Publication number
DK136976B
DK136976B DK169573AA DK169573A DK136976B DK 136976 B DK136976 B DK 136976B DK 169573A A DK169573A A DK 169573AA DK 169573 A DK169573 A DK 169573A DK 136976 B DK136976 B DK 136976B
Authority
DK
Denmark
Prior art keywords
trifluoromethylphenoxy
chlorobenzyl
oxazoline
alpha
preparation
Prior art date
Application number
DK169573AA
Other languages
English (en)
Other versions
DK136976C (da
Inventor
William Alfred Bolhofer
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK136976B publication Critical patent/DK136976B/da
Application granted granted Critical
Publication of DK136976C publication Critical patent/DK136976C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK169573AA 1972-04-11 1973-03-28 Analogifremgangsmåde til fremstilling af 2-(alfa-(3-trifluormethylphenoxy)-4-chlorbenzyl)-2-oxazolin eller syreadditionssalte deraf. DK136976B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00243480A US3816446A (en) 1972-04-11 1972-04-11 (alpha-(3-trifluoromethylphenoxy)-4-chlorobenzyl)heterocycles

Publications (2)

Publication Number Publication Date
DK136976B true DK136976B (da) 1977-12-27
DK136976C DK136976C (da) 1978-06-05

Family

ID=22918919

Family Applications (1)

Application Number Title Priority Date Filing Date
DK169573AA DK136976B (da) 1972-04-11 1973-03-28 Analogifremgangsmåde til fremstilling af 2-(alfa-(3-trifluormethylphenoxy)-4-chlorbenzyl)-2-oxazolin eller syreadditionssalte deraf.

Country Status (9)

Country Link
US (1) US3816446A (da)
JP (1) JPS5030620B2 (da)
CH (1) CH589636A5 (da)
DE (1) DE2318002A1 (da)
DK (1) DK136976B (da)
FR (1) FR2182952B1 (da)
GB (1) GB1388790A (da)
NL (1) NL7304333A (da)
SE (1) SE380524B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953465A (en) * 1972-04-11 1976-04-27 Merck & Co., Inc. 2-[α-(3-Trifluoromethylphenoxyl)-4-chlorobenzyl]oxazole and methods for preparing the same
US3953490A (en) * 1972-07-13 1976-04-27 Merck & Co., Inc. Preparation of (3-trifluoromethylphenoxy)(4-chlorophenyl)acetonitrile
JPS50116306U (da) * 1974-03-05 1975-09-22
JPS50137193U (da) * 1974-04-25 1975-11-12
JPS5111502A (ja) * 1974-07-19 1976-01-29 Matsushita Electric Ind Co Ltd Senkyokusochi
JPS544877Y2 (da) * 1976-12-03 1979-03-01
DE3161525D1 (en) * 1980-03-05 1984-01-05 Ciba Geigy Ag Herbicidally active 2-nitro-5-phenoxyphenyl oxazoles, oxazines, imidazoles, pyrimidines and thiazoles, their preparation and their use
US4870187A (en) * 1988-08-23 1989-09-26 Bristol-Myers Company Antihypercholesterolemic tetrazol-1-yl compounds
FR2766821A1 (fr) * 1997-07-29 1999-02-05 Sanofi Sa Derives de 1,3-oxazolinyl-biphenyle, leur procede de preparation et leur utilisation comme intermediaires de synthese
WO2002064094A2 (en) * 2001-02-09 2002-08-22 Merck & Co., Inc. 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders
RU2006133284A (ru) * 2004-02-18 2008-03-27 Метаболекс Альфа-(трифторметилзамещенные арилокси, ариламино, арилтио или арилметил)трифторметилзамещенные фенилуксусные кислоты и производные как противодиабетические средства
US7323480B2 (en) 2004-05-25 2008-01-29 Metabolex, Inc. Substituted triazoles as modulators of PPAR and methods of their preparation

Also Published As

Publication number Publication date
SE380524B (sv) 1975-11-10
NL7304333A (da) 1973-10-15
US3816446A (en) 1974-06-11
CH589636A5 (da) 1977-07-15
JPS497275A (da) 1974-01-22
DE2318002A1 (de) 1973-10-31
FR2182952A1 (da) 1973-12-14
DK136976C (da) 1978-06-05
GB1388790A (en) 1975-03-26
JPS5030620B2 (da) 1975-10-02
FR2182952B1 (da) 1975-10-31

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