DK135576B - Analogifremgangsmåde til fremstilling af 1,4-methano- eller 1,4-ethano-tetrahydronaphthyloxyaminopropanoler eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af 1,4-methano- eller 1,4-ethano-tetrahydronaphthyloxyaminopropanoler eller syreadditionssalte deraf.

Info

Publication number
DK135576B
DK135576B DK515372AA DK515372A DK135576B DK 135576 B DK135576 B DK 135576B DK 515372A A DK515372A A DK 515372AA DK 515372 A DK515372 A DK 515372A DK 135576 B DK135576 B DK 135576B
Authority
DK
Denmark
Prior art keywords
tetrahydronaphthyloxyaminopropanols
ethano
methano
preparation
acid addition
Prior art date
Application number
DK515372AA
Other languages
English (en)
Other versions
DK135576C (da
Inventor
Francesco Lauria
Vittorio Vecchietti
Mario Bergamaschi
Raffaele Tommasini
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of DK135576B publication Critical patent/DK135576B/da
Application granted granted Critical
Publication of DK135576C publication Critical patent/DK135576C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/38Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK515372AA 1971-10-21 1972-10-19 Analogifremgangsmåde til fremstilling af 1,4-methano- eller 1,4-ethano-tetrahydronaphthyloxyaminopropanoler eller syreadditionssalte deraf. DK135576B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT3012471 1971-10-21

Publications (2)

Publication Number Publication Date
DK135576B true DK135576B (da) 1977-05-23
DK135576C DK135576C (da) 1977-10-31

Family

ID=11229158

Family Applications (1)

Application Number Title Priority Date Filing Date
DK515372AA DK135576B (da) 1971-10-21 1972-10-19 Analogifremgangsmåde til fremstilling af 1,4-methano- eller 1,4-ethano-tetrahydronaphthyloxyaminopropanoler eller syreadditionssalte deraf.

Country Status (21)

Country Link
JP (1) JPS515379B2 (da)
AT (1) AT318563B (da)
AU (1) AU471732B2 (da)
BE (1) BE790188R (da)
CA (1) CA992983A (da)
CH (1) CH565741A5 (da)
CS (1) CS161064B2 (da)
DE (1) DE2251095C3 (da)
DK (1) DK135576B (da)
FR (1) FR2157897B2 (da)
GB (1) GB1351557A (da)
HK (1) HK9377A (da)
HU (1) HU165185B (da)
IL (1) IL40610A (da)
KE (1) KE2693A (da)
MY (1) MY7700158A (da)
NL (1) NL153516B (da)
NO (1) NO130643C (da)
SE (1) SE389103B (da)
SU (1) SU496722A3 (da)
ZA (1) ZA727459B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1436860A (en) * 1972-12-18 1976-05-26 Syntex Inc 5,8-dihydro-5,8-methanonaphthalene cardiovascular agents
JPS52120690A (en) * 1976-04-02 1977-10-11 Fujitsu Ltd Radiation semi-conductor device

Also Published As

Publication number Publication date
CA992983A (en) 1976-07-13
DE2251095C3 (de) 1976-01-02
BE790188R (fr) 1973-04-17
CS161064B2 (da) 1975-05-04
ZA727459B (en) 1974-05-29
FR2157897B2 (da) 1975-06-20
IL40610A (en) 1975-04-25
NL7214106A (da) 1973-04-25
JPS4849750A (da) 1973-07-13
DE2251095A1 (de) 1973-05-10
DE2251095B2 (de) 1975-05-07
JPS515379B2 (da) 1976-02-19
GB1351557A (en) 1974-05-01
CH565741A5 (da) 1975-08-29
HU165185B (da) 1974-07-27
KE2693A (en) 1977-02-11
HK9377A (en) 1977-02-25
AU471732B2 (en) 1976-04-29
SU496722A3 (ru) 1975-12-25
NO130643C (da) 1975-01-15
DK135576C (da) 1977-10-31
AT318563B (de) 1974-10-25
MY7700158A (en) 1977-12-31
NL153516B (nl) 1977-06-15
FR2157897A2 (da) 1973-06-08
IL40610A0 (en) 1972-12-29
NO130643B (da) 1974-10-07
SE389103B (sv) 1976-10-25
AU4707772A (en) 1974-04-04

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