DK135531B - Process for the preparation of 2,4-diamino-5-benzyl-pyrimidines. - Google Patents

Process for the preparation of 2,4-diamino-5-benzyl-pyrimidines.

Info

Publication number
DK135531B
DK135531B DK691073AA DK691073A DK135531B DK 135531 B DK135531 B DK 135531B DK 691073A A DK691073A A DK 691073AA DK 691073 A DK691073 A DK 691073A DK 135531 B DK135531 B DK 135531B
Authority
DK
Denmark
Prior art keywords
pyrimidines
diamino
benzyl
preparation
Prior art date
Application number
DK691073AA
Other languages
Danish (da)
Other versions
DK135531C (en
Inventor
Percy Manchand
Perry Rosen
Pius Anton Wehrli
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK135531B publication Critical patent/DK135531B/en
Application granted granted Critical
Publication of DK135531C publication Critical patent/DK135531C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK691073AA 1972-12-21 1973-12-19 Process for the preparation of 2,4-diamino-5-benzyl-pyrimidines. DK135531B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31750072A 1972-12-21 1972-12-21

Publications (2)

Publication Number Publication Date
DK135531B true DK135531B (en) 1977-05-16
DK135531C DK135531C (en) 1977-10-10

Family

ID=23233931

Family Applications (1)

Application Number Title Priority Date Filing Date
DK691073AA DK135531B (en) 1972-12-21 1973-12-19 Process for the preparation of 2,4-diamino-5-benzyl-pyrimidines.

Country Status (15)

Country Link
JP (1) JPS4988886A (en)
AT (1) AT339315B (en)
AU (1) AU476694B2 (en)
BE (1) BE808870A (en)
CA (1) CA986937A (en)
CH (1) CH592065A5 (en)
DE (1) DE2363533A1 (en)
DK (1) DK135531B (en)
FR (1) FR2211463B1 (en)
GB (1) GB1411170A (en)
HU (1) HU169082B (en)
IL (1) IL43658A (en)
NL (1) NL7317484A (en)
PH (1) PH12708A (en)
ZA (1) ZA738760B (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL122146C (en) * 1960-09-02
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
GB1407971A (en) * 1971-04-16 1975-10-01 Wellcome Found 2,4-diamino -4-3,4,5-triethoxybenzyl pyrimidine and methods of preparation therefor
BE792096A (en) * 1971-12-01 1973-05-30 Hoffmann La Roche NEW BENZYLPYRIMIDINES
BE795023A (en) * 1972-02-07 1973-08-06 Hoffmann La Roche NEW BENZYLPYRIMIDINES

Also Published As

Publication number Publication date
ATA1070773A (en) 1977-02-15
HU169082B (en) 1976-09-28
DE2363533A1 (en) 1974-06-27
GB1411170A (en) 1975-10-29
PH12708A (en) 1979-07-20
FR2211463B1 (en) 1979-05-11
ZA738760B (en) 1974-08-28
BE808870A (en) 1974-06-20
FR2211463A1 (en) 1974-07-19
IL43658A0 (en) 1974-03-14
AU476694B2 (en) 1976-09-30
CA986937A (en) 1976-04-06
JPS4988886A (en) 1974-08-24
AT339315B (en) 1977-10-10
CH592065A5 (en) 1977-10-14
NL7317484A (en) 1974-06-25
DK135531C (en) 1977-10-10
IL43658A (en) 1976-12-31
AU6275573A (en) 1975-05-22

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