DK134816B - Analogifremgangsmåde til fremstilling af estre af 11beta, 17alfa, 21-trihydroxy-16beta-methylpregna-1,4,8-trien-3,20-dion. - Google Patents

Analogifremgangsmåde til fremstilling af estre af 11beta, 17alfa, 21-trihydroxy-16beta-methylpregna-1,4,8-trien-3,20-dion.

Info

Publication number
DK134816B
DK134816B DK440773AA DK440773A DK134816B DK 134816 B DK134816 B DK 134816B DK 440773A A DK440773A A DK 440773AA DK 440773 A DK440773 A DK 440773A DK 134816 B DK134816 B DK 134816B
Authority
DK
Denmark
Prior art keywords
16beta
methylpregna
11beta
17alpha
triene
Prior art date
Application number
DK440773AA
Other languages
Danish (da)
English (en)
Other versions
DK134816C (ja
Inventor
Gordon Hanley Phillipps
Peter John May
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of DK134816B publication Critical patent/DK134816B/da
Application granted granted Critical
Publication of DK134816C publication Critical patent/DK134816C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
DK440773AA 1972-08-11 1973-08-10 Analogifremgangsmåde til fremstilling af estre af 11beta, 17alfa, 21-trihydroxy-16beta-methylpregna-1,4,8-trien-3,20-dion. DK134816B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3765672A GB1440064A (en) 1972-08-11 1972-08-11 Delta8-9- steroids of the pregnane series

Publications (2)

Publication Number Publication Date
DK134816B true DK134816B (da) 1977-01-24
DK134816C DK134816C (ja) 1977-08-15

Family

ID=10398038

Family Applications (1)

Application Number Title Priority Date Filing Date
DK440773AA DK134816B (da) 1972-08-11 1973-08-10 Analogifremgangsmåde til fremstilling af estre af 11beta, 17alfa, 21-trihydroxy-16beta-methylpregna-1,4,8-trien-3,20-dion.

Country Status (17)

Country Link
US (1) US3845085A (ja)
JP (1) JPS4985061A (ja)
AU (1) AU474366B2 (ja)
BE (1) BE803462A (ja)
CA (1) CA1016535A (ja)
CH (1) CH589669A5 (ja)
DE (1) DE2340656A1 (ja)
DK (1) DK134816B (ja)
ES (1) ES417737A1 (ja)
FR (1) FR2195452B1 (ja)
GB (1) GB1440064A (ja)
IE (1) IE38074B1 (ja)
IL (1) IL42943A (ja)
LU (1) LU68210A1 (ja)
NL (1) NL7311070A (ja)
PH (1) PH9642A (ja)
SE (1) SE396952B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2448662C2 (de) * 1974-10-09 1983-07-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen 6α-Fluor-16α-methyl-1,4,8-pregnatrien-3,20-dion-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US4225597A (en) * 1976-10-01 1980-09-30 Schering Corporation Beclomethasone dipropionate-hexane solvate and aerosols prepared therefrom
DE2645104C2 (de) * 1976-10-04 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen 11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung
NL7802905A (nl) * 1977-04-21 1978-10-24 Hoffmann La Roche Werkwijze voor het bereiden van d-homosteroiden.
GB1571629A (en) * 1977-11-30 1980-07-16 Fisons Ltd Pharmaceutical compositions containing beclomethasone dipropionate
JPS5653700A (en) * 1979-10-09 1981-05-13 Mitsubishi Chem Ind Ltd Production of 9alpha-chloro-11beta-hydroxy-corticosteroid
JP7095304B2 (ja) 2018-02-15 2022-07-05 株式会社リコー 分光特性取得装置、画像形成装置、画像形成システム、画像形成装置の管理システム、及び画像形成装置の管理方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1026160A (en) * 1964-04-29 1966-04-14 American Cyanamid Co Pregnatrienes

Also Published As

Publication number Publication date
DE2340656A1 (de) 1974-02-28
BE803462A (fr) 1974-02-11
IE38074L (en) 1974-02-11
SE396952B (sv) 1977-10-10
NL7311070A (ja) 1974-02-13
CA1016535A (en) 1977-08-30
AU474366B2 (en) 1976-07-22
LU68210A1 (ja) 1973-10-16
IL42943A (en) 1978-04-30
FR2195452B1 (ja) 1976-08-13
JPS4985061A (ja) 1974-08-15
PH9642A (en) 1976-01-26
US3845085A (en) 1974-10-29
CH589669A5 (ja) 1977-07-15
ES417737A1 (es) 1976-02-16
AU5914273A (en) 1975-02-13
FR2195452A1 (ja) 1974-03-08
IE38074B1 (en) 1977-12-21
IL42943A0 (en) 1973-11-28
GB1440064A (en) 1976-06-23
DK134816C (ja) 1977-08-15

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