CA1016535A - .delta. 8,9 steroids of the pregnane series - Google Patents

.delta. 8,9 steroids of the pregnane series

Info

Publication number
CA1016535A
CA1016535A CA178,557A CA178557A CA1016535A CA 1016535 A CA1016535 A CA 1016535A CA 178557 A CA178557 A CA 178557A CA 1016535 A CA1016535 A CA 1016535A
Authority
CA
Canada
Prior art keywords
steroids
delta
pregnane series
pregnane
series
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA178,557A
Other languages
English (en)
Other versions
CA178557S (en
Inventor
Gordon H. Phillipps
Peter J. May
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Application granted granted Critical
Publication of CA1016535A publication Critical patent/CA1016535A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CA178,557A 1972-08-11 1973-08-10 .delta. 8,9 steroids of the pregnane series Expired CA1016535A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3765672A GB1440064A (en) 1972-08-11 1972-08-11 Delta8-9- steroids of the pregnane series

Publications (1)

Publication Number Publication Date
CA1016535A true CA1016535A (en) 1977-08-30

Family

ID=10398038

Family Applications (1)

Application Number Title Priority Date Filing Date
CA178,557A Expired CA1016535A (en) 1972-08-11 1973-08-10 .delta. 8,9 steroids of the pregnane series

Country Status (17)

Country Link
US (1) US3845085A (ja)
JP (1) JPS4985061A (ja)
AU (1) AU474366B2 (ja)
BE (1) BE803462A (ja)
CA (1) CA1016535A (ja)
CH (1) CH589669A5 (ja)
DE (1) DE2340656A1 (ja)
DK (1) DK134816B (ja)
ES (1) ES417737A1 (ja)
FR (1) FR2195452B1 (ja)
GB (1) GB1440064A (ja)
IE (1) IE38074B1 (ja)
IL (1) IL42943A (ja)
LU (1) LU68210A1 (ja)
NL (1) NL7311070A (ja)
PH (1) PH9642A (ja)
SE (1) SE396952B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2448662C2 (de) * 1974-10-09 1983-07-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen 6α-Fluor-16α-methyl-1,4,8-pregnatrien-3,20-dion-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US4225597A (en) * 1976-10-01 1980-09-30 Schering Corporation Beclomethasone dipropionate-hexane solvate and aerosols prepared therefrom
DE2645104C2 (de) * 1976-10-04 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen 11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung
NL7802905A (nl) * 1977-04-21 1978-10-24 Hoffmann La Roche Werkwijze voor het bereiden van d-homosteroiden.
GB1571629A (en) * 1977-11-30 1980-07-16 Fisons Ltd Pharmaceutical compositions containing beclomethasone dipropionate
JPS5653700A (en) * 1979-10-09 1981-05-13 Mitsubishi Chem Ind Ltd Production of 9alpha-chloro-11beta-hydroxy-corticosteroid
JP7095304B2 (ja) 2018-02-15 2022-07-05 株式会社リコー 分光特性取得装置、画像形成装置、画像形成システム、画像形成装置の管理システム、及び画像形成装置の管理方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1026160A (en) * 1964-04-29 1966-04-14 American Cyanamid Co Pregnatrienes

Also Published As

Publication number Publication date
DE2340656A1 (de) 1974-02-28
BE803462A (fr) 1974-02-11
IE38074L (en) 1974-02-11
SE396952B (sv) 1977-10-10
NL7311070A (ja) 1974-02-13
AU474366B2 (en) 1976-07-22
LU68210A1 (ja) 1973-10-16
IL42943A (en) 1978-04-30
FR2195452B1 (ja) 1976-08-13
JPS4985061A (ja) 1974-08-15
PH9642A (en) 1976-01-26
US3845085A (en) 1974-10-29
CH589669A5 (ja) 1977-07-15
ES417737A1 (es) 1976-02-16
AU5914273A (en) 1975-02-13
DK134816B (da) 1977-01-24
FR2195452A1 (ja) 1974-03-08
IE38074B1 (en) 1977-12-21
IL42943A0 (en) 1973-11-28
GB1440064A (en) 1976-06-23
DK134816C (ja) 1977-08-15

Similar Documents

Publication Publication Date Title
CA1021318A (en) 11,11-alkylidene steroids
CA1027109A (en) PROCESS FOR THE PREPARATION OF 17.alpha.-ESTERS OF 17.alpha., 21-DIHYDROXY-20-OXO STEROIDS
CA1016535A (en) .delta. 8,9 steroids of the pregnane series
CA1006156A (en) Steroids of the pregnane series
CA1020546A (en) 21-sulfinyl steroids
AU468273B2 (en) 16, 17-cyclopropa steroids ofthe androstane series
CA969175A (en) 6.alpha.,9.alpha.-DIFLUOROSTEROIDS OF THE PREGNANE SERIES AND PROCESSES FOR THEIR MANUFACTURE
AU492089B2 (en) Novel 11,11-alkylidene steroids
CA858558A (en) 4,6-dichloro-.delta.4,6-steroids of the pregnane and androstane series
CA812226A (en) Reductive aromatization of .delta.1,4-3-keto-10-methyl steroids of the androstane series
CA913064A (en) Selective 3 or 9(11) - enolisation of steroid-1,4-diene-3,11-diones
CA897682A (en) Process for the manufacture of .delta.14-20-keto-21-dialkoxy steroids
CA892572A (en) Steroids of the pregnane series
CA914148A (en) Preparation of 9, 11-dichloro steroids
CA894782A (en) MICROBIOLOGICAL PROCESS FOR PRODUCING 11.alpha.-HYDROXY-3-OXO-.DELTA.1,4-STEROIDS OF THE PREGNANE AND ANDROSTANE SERIES
CA893110A (en) 3,20-DIOXO 16.alpha.,17.alpha.-DIHYDROXY 19-NOR PREGNA-4-ENE
AU443789B2 (en) 9,21-DIFLUORO-11b-HYDROXY-16-METHYLENE-17-ACYLOXY-PREGNANE STEROIDS
CA895285A (en) 1.alpha.,2.alpha.;6.beta.,7.beta.-DIMETHYLENE STEROIDS
CA863337A (en) .DELTA.1,4-PREGNADIENE-17.alpha.,21-DIOL-3,11,20-TRIONE
CA910298A (en) 16-methyl steroids and process for the preparation thereof
AU424679B2 (en) NOVEL 9 p, 10 STEROIDS
CA887639A (en) 2,3-EPITHIO-5.alpha.-ANDROST-6-ENE STEROIDS
AU452240B2 (en) 21 fluoro-16, 17-dihydroxy pregnane compounds and their derivatives
CA779285A (en) 1,2.alpha.-METHYLENE STEROIDS OF THE PREGNANE SERIES AND PROCESS FOR THEIR MANUFACTURE
CA899850A (en) 11.beta.-HALOGENATED STEROIDS AND PROCESSES FOR THEIR PREPARATION