DK130966B - Analogous process for the preparation of 1- (3-cyano-3,3-diphenylpropyl) -4-phenylpiperidine-4-carboxylic acid derivatives or acid addition salts thereof. - Google Patents

Analogous process for the preparation of 1- (3-cyano-3,3-diphenylpropyl) -4-phenylpiperidine-4-carboxylic acid derivatives or acid addition salts thereof.

Info

Publication number
DK130966B
DK130966B DK607671AA DK607671A DK130966B DK 130966 B DK130966 B DK 130966B DK 607671A A DK607671A A DK 607671AA DK 607671 A DK607671 A DK 607671A DK 130966 B DK130966 B DK 130966B
Authority
DK
Denmark
Prior art keywords
diphenylpropyl
phenylpiperidine
cyano
preparation
addition salts
Prior art date
Application number
DK607671AA
Other languages
Danish (da)
Other versions
DK130966C (en
Inventor
E M Kreider
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB5968670A external-priority patent/GB1356117A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of DK130966B publication Critical patent/DK130966B/en
Application granted granted Critical
Publication of DK130966C publication Critical patent/DK130966C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK607671AA 1970-12-16 1971-12-13 Analogous process for the preparation of 1- (3-cyano-3,3-diphenylpropyl) -4-phenylpiperidine-4-carboxylic acid derivatives or acid addition salts thereof. DK130966B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5968670A GB1356117A (en) 1970-12-16 1970-12-16 1-3-cyano-3,3-diphenylpropyl-4-phenylpiperidine-4-carboxylic acid derivatives

Publications (2)

Publication Number Publication Date
DK130966B true DK130966B (en) 1975-05-12
DK130966C DK130966C (en) 1975-10-06

Family

ID=10484227

Family Applications (2)

Application Number Title Priority Date Filing Date
DK607671AA DK130966B (en) 1970-12-16 1971-12-13 Analogous process for the preparation of 1- (3-cyano-3,3-diphenylpropyl) -4-phenylpiperidine-4-carboxylic acid derivatives or acid addition salts thereof.
DK607571AA DK136037B (en) 1970-12-16 1971-12-13 Analogous process for the preparation of 1- (3-cyano-3,3-diphenylpropyl) -4-phenylpiperidine-4-carboxylic acid derivatives or acid addition salts thereof.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK607571AA DK136037B (en) 1970-12-16 1971-12-13 Analogous process for the preparation of 1- (3-cyano-3,3-diphenylpropyl) -4-phenylpiperidine-4-carboxylic acid derivatives or acid addition salts thereof.

Country Status (9)

Country Link
JP (1) JPS5542996B1 (en)
CA (1) CA918157A (en)
CY (1) CY925A (en)
DK (2) DK130966B (en)
ES (4) ES397911A1 (en)
IE (2) IE35890B1 (en)
SE (2) SE370543B (en)
YU (2) YU34990B (en)
ZA (2) ZA718380B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6115962U (en) * 1984-06-30 1986-01-30 儀介 野沢 Pig tank

Also Published As

Publication number Publication date
SE370542B (en) 1974-10-21
DK130966C (en) 1975-10-06
IE35890B1 (en) 1976-06-23
IE35889L (en) 1972-06-16
DK136037C (en) 1978-01-02
CY925A (en) 1977-12-23
ES400479A1 (en) 1975-01-16
JPS5542996B1 (en) 1980-11-04
ES397912A1 (en) 1975-04-16
ES397911A1 (en) 1975-04-16
IE35889B1 (en) 1976-06-23
ES400478A1 (en) 1975-01-01
IE35890L (en) 1972-06-16
DK136037B (en) 1977-08-01
SE370543B (en) 1974-10-21
ZA718379B (en) 1973-02-28
CA918157A (en) 1973-01-02
YU248678A (en) 1979-12-31
YU248778A (en) 1979-12-31
YU34990B (en) 1980-06-30
YU34991B (en) 1980-06-30
ZA718380B (en) 1973-02-28

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