DK129791B - Fremgangsmåde til fremstilling af 6,6-difluor-17α,21-dihydroxypregn-4-en-3,20-dioner. - Google Patents

Fremgangsmåde til fremstilling af 6,6-difluor-17α,21-dihydroxypregn-4-en-3,20-dioner.

Info

Publication number
DK129791B
DK129791B DK191271AA DK191271A DK129791B DK 129791 B DK129791 B DK 129791B DK 191271A A DK191271A A DK 191271AA DK 191271 A DK191271 A DK 191271A DK 129791 B DK129791 B DK 129791B
Authority
DK
Denmark
Prior art keywords
dihydroxypregn
diones
difluoro
ene
preparation
Prior art date
Application number
DK191271AA
Other languages
Danish (da)
English (en)
Other versions
DK129791C (enExample
Inventor
R Scribner
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of DK129791B publication Critical patent/DK129791B/da
Application granted granted Critical
Publication of DK129791C publication Critical patent/DK129791C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
DK191271AA 1970-04-22 1971-04-21 Fremgangsmåde til fremstilling af 6,6-difluor-17α,21-dihydroxypregn-4-en-3,20-dioner. DK129791B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3100270A 1970-04-22 1970-04-22
US10566571A 1971-01-11 1971-01-11

Publications (2)

Publication Number Publication Date
DK129791B true DK129791B (da) 1974-11-18
DK129791C DK129791C (enExample) 1975-04-28

Family

ID=26706704

Family Applications (1)

Application Number Title Priority Date Filing Date
DK191271AA DK129791B (da) 1970-04-22 1971-04-21 Fremgangsmåde til fremstilling af 6,6-difluor-17α,21-dihydroxypregn-4-en-3,20-dioner.

Country Status (12)

Country Link
AR (1) AR193811A1 (enExample)
BE (1) BE765554A (enExample)
CA (1) CA942294A (enExample)
DE (1) DE2118752A1 (enExample)
DK (1) DK129791B (enExample)
ES (1) ES390111A1 (enExample)
FI (1) FI47093C (enExample)
FR (1) FR2092069B1 (enExample)
GB (3) GB1348941A (enExample)
IL (1) IL36428A (enExample)
NL (1) NL7105386A (enExample)
SE (1) SE368824B (enExample)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1468605A (fr) * 1959-05-11 1967-02-10 Upjohn Co Procédé de fabrication de la 6alpha-fluoro-16-méthyl-17alpha, 21-dihydroxy-4-prégnène-3, 20-dione et de ses 21 esters
US3546215A (en) * 1967-10-18 1970-12-08 Syntex Corp 6-gem-difluoro steroids

Also Published As

Publication number Publication date
GB1348941A (en) 1974-03-27
CA942294A (en) 1974-02-19
FR2092069B1 (enExample) 1974-08-23
FI47093C (fi) 1973-09-10
NL7105386A (enExample) 1971-10-26
SE368824B (enExample) 1974-07-22
IL36428A (en) 1975-05-22
FR2092069A1 (enExample) 1972-01-21
IL36428A0 (en) 1971-05-26
ES390111A1 (es) 1974-06-16
DE2118752A1 (de) 1971-11-04
GB1348942A (en) 1974-03-27
AR193811A1 (es) 1973-05-31
FI47093B (enExample) 1973-05-31
BE765554A (fr) 1971-10-11
GB1348943A (en) 1974-03-27
DK129791C (enExample) 1975-04-28

Similar Documents

Publication Publication Date Title
DK132174B (da) Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimider.
DK127640B (da) Fremgangsmåde til fremstilling af 3,20-dioxo-17α-21-dimethyl-19-norpregna-4,9-dien.
DK129339B (da) Analogifremgangsmåde til fremstilling af N-aminophenylamidiner.
DK140842B (da) Fremgangsmåde til fremstilling af 8,9-didebydro-10alfa-alkoxy-ergolener.
DK135455B (da) Fremgangsmåde til fremstilling af 7-halogen-7-desoxythiolincosaminider.
DK130467B (da) Fremgangsmåde til fremstilling af erythromycylaminer.
DK127812B (da) Analogifremgangsmåde til fremstilling af 3,5-dibrom-zearalan.
DK127778B (da) Fremgangsmåde til fremstilling af 3',4'-dideoxy-kenamycin B.
DK127977B (da) Fremgangsmåde til fremstilling af 6α-methyl-19-nor-pregnener.
DK122454B (da) Fremgangsmåde til fremstilling af 9α,21,21-triklor-11β-fluor-pregn-4-en-3,20-dioner.
DK128205B (da) Fremgangsmåde til fremstilling af 1-aryloxy-2-propanoler.
DK129453B (da) Analogifremgangsmåde til fremstilling af 1-aminoisoquinoliner.
DK137754B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.
DK126323B (da) Fremgangsmåde til fremstilling af 3β-hydroxy-5α-cardenolider eller -bufadienolider.
DK130308B (da) Fremgangsmåde til fremstilling af 13β-alkylgona-4,9,11-triener.
DK132121B (da) Fremgangsmåde til fremstilling af 17alfa-hydroxypregna-4,9(11)-dien-3,20-dion.
DK124127B (da) Analogifremgangsmåde til fremstilling af 3,20-dioxo-13β-ethyl-17α-methyl-18,19-di-nor-pregna-4,9-dien.
DK126937B (da) Fremgangsmåde til fremstilling af 4,6-dihalogen-16-alkyliden-17α-hydroxy-pregna-4,6-dien-3,20-dioner.
DK127110B (da) Fremgangsmåde til fremstilling af pyranosider af 3β-hydroxy-4-chlor-carda-4,20(22)-dienolider.
DK126186B (da) Fremgangsmåde til fremstilling af 13β-alkylgona-4,9-diener.
DK125790B (da) Fremgangsmåde til fremstilling af L-β-3,4-dihydroxyphenyl-α-alanin.
DK129138B (da) Fremgangsmåde til fremstilling af tuberactinomycin-N.
DK127414B (da) Analogifremgangsmåde til fremstilling af phenylhydrazider.
DK127852B (da) Analogifremgangsmåde til fremstilling af 22-substituerede cardenolidrhamnosider.
DK127115B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.