DK128117B - Analogifremgangsmåde til fremstilling af 2,6-diamino-9-(β-D-arabinofuranosyl)-purin. - Google Patents

Analogifremgangsmåde til fremstilling af 2,6-diamino-9-(β-D-arabinofuranosyl)-purin.

Info

Publication number
DK128117B
DK128117B DK581070AA DK581070A DK128117B DK 128117 B DK128117 B DK 128117B DK 581070A A DK581070A A DK 581070AA DK 581070 A DK581070 A DK 581070A DK 128117 B DK128117 B DK 128117B
Authority
DK
Denmark
Prior art keywords
arabinofuranosyl
diamino
purine
preparation
analogous process
Prior art date
Application number
DK581070AA
Other languages
Danish (da)
English (en)
Inventor
G Elion
R Strelitz
Original Assignee
Welicome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welicome Foundation Ltd filed Critical Welicome Foundation Ltd
Publication of DK128117B publication Critical patent/DK128117B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK581070AA 1969-11-17 1970-11-16 Analogifremgangsmåde til fremstilling af 2,6-diamino-9-(β-D-arabinofuranosyl)-purin. DK128117B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87744369A 1969-11-17 1969-11-17

Publications (1)

Publication Number Publication Date
DK128117B true DK128117B (da) 1974-03-04

Family

ID=25369972

Family Applications (1)

Application Number Title Priority Date Filing Date
DK581070AA DK128117B (da) 1969-11-17 1970-11-16 Analogifremgangsmåde til fremstilling af 2,6-diamino-9-(β-D-arabinofuranosyl)-purin.

Country Status (26)

Country Link
US (1) US3666856A (hu)
JP (1) JPS5429520B1 (hu)
AT (1) AT309696B (hu)
BE (1) BE759011A (hu)
BR (1) BR6915136D0 (hu)
CA (1) CA967564A (hu)
CH (2) CH555833A (hu)
CS (1) CS181701B2 (hu)
DE (1) DE2056327C2 (hu)
DK (1) DK128117B (hu)
ES (2) ES385590A1 (hu)
FI (1) FI54315C (hu)
FR (1) FR2073364B1 (hu)
GB (2) GB1338905A (hu)
HU (1) HU163812B (hu)
IE (1) IE34737B1 (hu)
IL (1) IL35658A (hu)
LU (1) LU62071A1 (hu)
MC (1) MC869A1 (hu)
NL (1) NL171589C (hu)
NO (1) NO128156B (hu)
PL (1) PL81167B1 (hu)
SE (1) SE385374B (hu)
YU (2) YU35033B (hu)
ZA (1) ZA707722B (hu)
ZM (1) ZM12970A1 (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4081534A (en) * 1973-09-11 1978-03-28 Burroughs Wellcome Co. Amino purine nucleosides as autoimmune suppressant agents
GB1562899A (en) * 1975-06-17 1980-03-19 Wellcome Found Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof
US4210745A (en) * 1978-01-04 1980-07-01 The United States Of America As Represented By The Department Of Health, Education And Welfare Procedure for the preparation of 9-β-D-arabinofuranosyl-2-fluoroadenine
DE3319282A1 (de) * 1983-05-27 1984-11-29 Gödecke AG, 1000 Berlin Verwendung von adenosin bei der behandlung von herpes
GB8712745D0 (en) * 1987-05-30 1987-07-01 Wellcome Found Antiviral compounds
CA1339964C (en) * 1988-03-16 1998-07-21 Dennis A. Carson Substituted adenine derivatives useful as therapeutic agents
IE882585L (en) * 1988-08-25 1990-02-25 Prendergast Patrick T Viral treatment system
US5292725A (en) * 1988-08-25 1994-03-08 Prendergast Patrick T Administering particular compounds against various parasites, mycoplasmas, other indications and other infections
US5681941A (en) * 1990-01-11 1997-10-28 Isis Pharmaceuticals, Inc. Substituted purines and oligonucleotide cross-linking
US5308837A (en) * 1990-08-22 1994-05-03 Merrell Dow Pharmaceuticals Inc. 5'-amine substituted adenosine analogs as immunosuppressants
US6338963B1 (en) 1994-07-25 2002-01-15 Neotherapeutics, Inc. Use of carbon monoxide dependent guanylyl cyclase modifiers to stimulate neuritogenesis
US6232463B1 (en) 1997-10-09 2001-05-15 Isis Pharmaceuticals, Inc. Substituted purines and oligonucleotide cross-linking
US6303617B1 (en) 1998-05-04 2001-10-16 Neotherapeutics, Inc. Serotonin-like 9-substituted hypoxanthine and methods of use
US6288069B1 (en) 1999-11-16 2001-09-11 Neotherapeutics, Inc. Use of 9-substituted hypoxanthine derivatives to stimulate regeneration of nervous tissue
US6407237B1 (en) 2001-02-21 2002-06-18 Neotherapeutics, Inc. Crystal forms of 9-substituted hypoxanthine derivatives
US6849735B1 (en) 2000-06-23 2005-02-01 Merck Eprova Ag Methods of synthesis for 9-substituted hypoxanthine derivatives
ES2385931T3 (es) 2000-07-07 2012-08-03 Spectrum Pharmaceuticals, Inc. MÉTODOS PARA EL TRATAMIENTO DE NEUROPATíA PERIFÉRICA INDUCIDA POR UNA ENFERMEDAD Y AFECCIONES RELACIONADAS.
US6759427B2 (en) 2001-04-20 2004-07-06 Spectrum Pharmaceuticals, Inc. Synthesis and methods of use of tetrahydroindolone analogues and derivatives
US20030055249A1 (en) * 2001-07-17 2003-03-20 Fick David B. Synthesis and methods of use of pyrimidine analogues and derivatives
CN105237602B (zh) * 2015-06-25 2018-05-18 新乡学院 一种2-氨基阿糖腺苷的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1070413A (en) * 1962-11-15 1967-06-01 Sankyo Co A process for preparing purine and pyrimidine nucleosides
US3407191A (en) * 1966-08-29 1968-10-22 Lilly Co Eli Adamantoate esters of nucleosides
JPH1097965A (ja) * 1996-09-20 1998-04-14 Sony Corp 生産管理方法

Also Published As

Publication number Publication date
ZM12970A1 (en) 1972-07-21
IE34737B1 (en) 1975-08-06
YU35033B (en) 1980-06-30
NL171589B (nl) 1982-11-16
FI54315B (fi) 1978-07-31
BE759011A (fr) 1971-05-17
YU201978A (en) 1979-12-31
NL7016766A (hu) 1971-05-19
PL81167B1 (hu) 1975-08-30
NL171589C (nl) 1983-04-18
FR2073364B1 (hu) 1974-03-22
HU163812B (hu) 1973-10-27
JPS5429520B1 (hu) 1979-09-25
CH555833A (de) 1974-11-15
BR6915136D0 (pt) 1973-04-19
YU280670A (en) 1979-12-31
IL35658A0 (en) 1971-01-28
ES385590A1 (es) 1973-10-01
CS181701B2 (en) 1978-03-31
ES413787A1 (es) 1976-01-16
DE2056327A1 (de) 1971-06-03
MC869A1 (fr) 1971-09-28
FI54315C (fi) 1978-11-10
SE385374B (sv) 1976-06-28
ZA707722B (en) 1972-06-28
CA967564A (en) 1975-05-13
IE34737L (en) 1971-05-17
GB1338905A (en) 1973-11-28
IL35658A (en) 1974-10-22
CH555344A (de) 1974-10-31
NO128156B (hu) 1973-10-08
LU62071A1 (hu) 1971-08-12
FR2073364A1 (hu) 1971-10-01
US3666856A (en) 1972-05-30
DE2056327C2 (de) 1984-10-11
AT309696B (de) 1973-08-27
GB1338906A (en) 1973-11-28
YU35034B (en) 1980-06-30

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Legal Events

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PBP Patent lapsed