DK1278721T3 - Fremgangsmåde til fremstilling af pyrazinforbindelser - Google Patents
Fremgangsmåde til fremstilling af pyrazinforbindelserInfo
- Publication number
- DK1278721T3 DK1278721T3 DK01925711T DK01925711T DK1278721T3 DK 1278721 T3 DK1278721 T3 DK 1278721T3 DK 01925711 T DK01925711 T DK 01925711T DK 01925711 T DK01925711 T DK 01925711T DK 1278721 T3 DK1278721 T3 DK 1278721T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- pyrazine
- pyrazine compounds
- trichlorophenyl
- diamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0010971.0A GB0010971D0 (en) | 2000-05-05 | 2000-05-05 | Process |
| PCT/GB2001/001929 WO2001085674A1 (en) | 2000-05-05 | 2001-05-02 | Process for the preparation of pyrazine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1278721T3 true DK1278721T3 (da) | 2007-10-01 |
Family
ID=9891108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01925711T DK1278721T3 (da) | 2000-05-05 | 2001-05-02 | Fremgangsmåde til fremstilling af pyrazinforbindelser |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6803464B2 (el) |
| EP (1) | EP1278721B1 (el) |
| JP (1) | JP2003532702A (el) |
| AT (1) | ATE365709T1 (el) |
| AU (1) | AU2001252395A1 (el) |
| CY (1) | CY1109090T1 (el) |
| DE (1) | DE60129122T2 (el) |
| DK (1) | DK1278721T3 (el) |
| ES (1) | ES2284640T3 (el) |
| GB (1) | GB0010971D0 (el) |
| PT (1) | PT1278721E (el) |
| WO (1) | WO2001085674A1 (el) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11400065B2 (en) | 2019-03-01 | 2022-08-02 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11839597B2 (en) | 2016-07-22 | 2023-12-12 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12128021B1 (en) | 2024-04-23 | 2024-10-29 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060182805A1 (en) * | 2005-02-15 | 2006-08-17 | Jazz Pharmaceuticals | Dosage form and method for sustained release of substituted pyrazine compound |
| WO2009146112A1 (en) * | 2008-04-02 | 2009-12-03 | University Of Virginia Patent Foundation | Compositions and methods for inhibiting sphingosine kinase |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA26473A1 (fr) | 1997-03-01 | 2004-12-20 | Glaxo Group Ltd | Composes pharmacologiquement actifs. |
| GB9818881D0 (en) * | 1998-08-28 | 1998-10-21 | Glaxo Group Ltd | Compounds |
-
2000
- 2000-05-05 GB GBGB0010971.0A patent/GB0010971D0/en not_active Ceased
-
2001
- 2001-05-02 JP JP2001582275A patent/JP2003532702A/ja active Pending
- 2001-05-02 AT AT01925711T patent/ATE365709T1/de active
- 2001-05-02 US US10/275,457 patent/US6803464B2/en not_active Expired - Fee Related
- 2001-05-02 AU AU2001252395A patent/AU2001252395A1/en not_active Abandoned
- 2001-05-02 EP EP01925711A patent/EP1278721B1/en not_active Expired - Lifetime
- 2001-05-02 DE DE60129122T patent/DE60129122T2/de not_active Expired - Lifetime
- 2001-05-02 DK DK01925711T patent/DK1278721T3/da active
- 2001-05-02 WO PCT/GB2001/001929 patent/WO2001085674A1/en active IP Right Grant
- 2001-05-02 ES ES01925711T patent/ES2284640T3/es not_active Expired - Lifetime
- 2001-05-02 PT PT01925711T patent/PT1278721E/pt unknown
-
2007
- 2007-09-25 CY CY20071101230T patent/CY1109090T1/el unknown
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11839597B2 (en) | 2016-07-22 | 2023-12-12 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12109186B2 (en) | 2016-07-22 | 2024-10-08 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11896572B2 (en) | 2016-07-22 | 2024-02-13 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11766418B2 (en) | 2016-07-22 | 2023-09-26 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12115142B2 (en) | 2016-07-22 | 2024-10-15 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11826335B2 (en) | 2016-07-22 | 2023-11-28 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12115145B2 (en) | 2016-07-22 | 2024-10-15 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12115143B2 (en) | 2016-07-22 | 2024-10-15 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12097176B2 (en) | 2016-07-22 | 2024-09-24 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12097175B2 (en) | 2016-07-22 | 2024-09-24 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12115144B2 (en) | 2016-07-22 | 2024-10-15 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11400065B2 (en) | 2019-03-01 | 2022-08-02 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12128021B1 (en) | 2024-04-23 | 2024-10-29 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
Also Published As
| Publication number | Publication date |
|---|---|
| DE60129122D1 (de) | 2007-08-09 |
| ES2284640T3 (es) | 2007-11-16 |
| US6803464B2 (en) | 2004-10-12 |
| WO2001085674A1 (en) | 2001-11-15 |
| GB0010971D0 (en) | 2000-06-28 |
| CY1109090T1 (el) | 2014-07-02 |
| EP1278721B1 (en) | 2007-06-27 |
| DE60129122T2 (de) | 2007-10-11 |
| AU2001252395A1 (en) | 2001-11-20 |
| ATE365709T1 (de) | 2007-07-15 |
| PT1278721E (pt) | 2007-07-13 |
| JP2003532702A (ja) | 2003-11-05 |
| US20030149053A1 (en) | 2003-08-07 |
| EP1278721A1 (en) | 2003-01-29 |
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