DK124949B - Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater. - Google Patents

Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.

Info

Publication number
DK124949B
DK124949B DK664466AA DK664466A DK124949B DK 124949 B DK124949 B DK 124949B DK 664466A A DK664466A A DK 664466AA DK 664466 A DK664466 A DK 664466A DK 124949 B DK124949 B DK 124949B
Authority
DK
Denmark
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
DK664466AA
Other languages
English (en)
Inventor
A Stempel
L Sternbach
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to DK456870A priority Critical patent/DK134671B/da
Publication of DK124949B publication Critical patent/DK124949B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK664466AA 1965-02-08 1966-12-22 Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater. DK124949B (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK456870A DK134671B (da) 1965-02-08 1970-09-04 Benzophenonderivater til anvendelse som mellemprodukter ved fremstilling af 1,4-benzodiazepinderivater.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43117465A 1965-02-08 1965-02-08
US519017A US3405123A (en) 1965-02-08 1966-01-06 Process for preparing 1, 4-benzodiazepin-2-ones

Publications (1)

Publication Number Publication Date
DK124949B true DK124949B (da) 1972-12-11

Family

ID=27028912

Family Applications (2)

Application Number Title Priority Date Filing Date
DK54566AA DK129925B (da) 1965-02-08 1966-02-02 Fremgangsmåde til fremstilling af benzophenonderivater.
DK664466AA DK124949B (da) 1965-02-08 1966-12-22 Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK54566AA DK129925B (da) 1965-02-08 1966-02-02 Fremgangsmåde til fremstilling af benzophenonderivater.

Country Status (11)

Country Link
US (1) US3405123A (da)
BE (1) BE676046A (da)
BR (1) BR6676844D0 (da)
CH (1) CH464944A (da)
DE (2) DE1695157A1 (da)
DK (2) DK129925B (da)
GB (1) GB1081946A (da)
IL (1) IL25056A (da)
NL (2) NL6601273A (da)
SE (2) SE371437B (da)
YU (1) YU33951B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005021005A2 (en) * 2003-08-28 2005-03-10 Ranbaxy Laboratories Limited Process for the preparation of 1,4-benzodiazepine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3247187A (en) * 1963-07-10 1966-04-19 Hoffmann La Roche Oxidation of 1, 4-benzodiazepines to 1, 4-benzodiazepin-2-ones

Also Published As

Publication number Publication date
BR6676844D0 (pt) 1973-12-26
NL7000509A (da) 1970-03-23
SE334619B (da) 1971-05-03
DE1568742A1 (de) 1970-04-02
NL6601273A (da) 1966-08-09
SE371437B (da) 1974-11-18
YU165370A (en) 1978-02-28
GB1081946A (en) 1967-09-06
YU33951B (en) 1978-09-08
BE676046A (da) 1966-08-04
DK129925B (da) 1974-12-02
US3405123A (en) 1968-10-08
CH464944A (de) 1968-11-15
IL25056A (en) 1969-11-12
DE1695157A1 (de) 1970-12-17
DK129925C (da) 1975-05-20

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