DK120542B - Fremgangsmåde til fremstilling af α-(2-methyl-3-indolyl)-eddikesyrer. - Google Patents

Fremgangsmåde til fremstilling af α-(2-methyl-3-indolyl)-eddikesyrer.

Info

Publication number
DK120542B
DK120542B DK163868AA DK163868A DK120542B DK 120542 B DK120542 B DK 120542B DK 163868A A DK163868A A DK 163868AA DK 163868 A DK163868 A DK 163868A DK 120542 B DK120542 B DK 120542B
Authority
DK
Denmark
Prior art keywords
indolyl
methyl
preparation
acetic acids
acetic
Prior art date
Application number
DK163868AA
Other languages
Danish (da)
English (en)
Inventor
M Sletzinger
R Firestone
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK120542B publication Critical patent/DK120542B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/281-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
DK163868AA 1965-10-07 1968-04-10 Fremgangsmåde til fremstilling af α-(2-methyl-3-indolyl)-eddikesyrer. DK120542B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US493885A US3322786A (en) 1965-10-07 1965-10-07 3-indolyl aliphatic acids

Publications (1)

Publication Number Publication Date
DK120542B true DK120542B (da) 1971-06-14

Family

ID=23962103

Family Applications (1)

Application Number Title Priority Date Filing Date
DK163868AA DK120542B (da) 1965-10-07 1968-04-10 Fremgangsmåde til fremstilling af α-(2-methyl-3-indolyl)-eddikesyrer.

Country Status (12)

Country Link
US (1) US3322786A (US06534493-20030318-C00166.png)
BE (1) BE687885A (US06534493-20030318-C00166.png)
BR (1) BR6683338D0 (US06534493-20030318-C00166.png)
CH (2) CH471123A (US06534493-20030318-C00166.png)
DE (1) DE1620039A1 (US06534493-20030318-C00166.png)
DK (1) DK120542B (US06534493-20030318-C00166.png)
ES (1) ES332330A1 (US06534493-20030318-C00166.png)
FR (1) FR1495978A (US06534493-20030318-C00166.png)
GB (1) GB1136489A (US06534493-20030318-C00166.png)
IL (1) IL26577A (US06534493-20030318-C00166.png)
NL (1) NL6614158A (US06534493-20030318-C00166.png)
SE (2) SE335127B (US06534493-20030318-C00166.png)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA957281A (en) * 1970-02-03 1974-11-05 Nathan N. Share Pharmaceutical compositions containing indole-3-acetic acid derivatives as a skeletal muscle stimulant
DE3531658A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
US5288743A (en) * 1992-11-20 1994-02-22 Abbott Laboratories Indole carboxylate derivatives which inhibit leukotriene biosynthesis

Also Published As

Publication number Publication date
FR1495978A (fr) 1967-09-22
BR6683338D0 (pt) 1973-12-04
NL6614158A (US06534493-20030318-C00166.png) 1967-04-10
US3322786A (en) 1967-05-30
GB1136489A (en) 1968-12-11
CH472405A (de) 1969-05-15
SE312805B (US06534493-20030318-C00166.png) 1969-07-28
IL26577A (en) 1970-12-24
ES332330A1 (es) 1967-07-16
SE335127B (US06534493-20030318-C00166.png) 1971-05-17
CH471123A (de) 1969-04-15
DE1620039A1 (de) 1970-02-05
BE687885A (US06534493-20030318-C00166.png) 1967-04-06

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